Genetic disorder

A genetic disorder can be caused by any defect in an individual's genetic health problems composition. It can range from small to substantial, depending on whether there is a modest mutation in a single gene's DNA strand or a large abnormality of the entire chromosome or set of chromosomes. It is important to recognize women health issues. 

Some genetic disorders are passed down from parents, run in families, or are acquired at random due to mutations or alterations in a single gene or collection of genes. It could be caused by environmental factors, pollutants, chemical exposure, radiation, and so on.

Genetic disorder

The following factors raise the chance of genetic disorders:

  • After 35 years of age, the incidence rises dramatically.
  • History of the family
  • Miscarriages and birth abnormalities have occurred in the past.
  • Have a history of cancer and have received chemo/radiotherapy.

Before planning a pregnancy or receiving treatment, this group of patients should seek pre-genetic disorder counseling. They should have pre-genetic tests to determine the likelihood of passing the disease on to the child.

Genetic health problems are more common in women. However, there are tests that may be used to detect them. Women health issues are a major concern to society.

This illness group includes ovarian cancer, breast cancer, cardiovascular disease, diabetes, and obesity, all of which are serious public health concerns that disproportionately or primarily affect women. While it is well acknowledged that genes are the body's blueprint and the basic physical and functional unit of heredity, few people give genetic disorders or anomalies that may be influencing their health much thought. 

Women, in particular, are unaware of how much their genes influence their health and how certain hereditary illnesses can be avoided to ensure a healthy life.

The most common genetic disorders or genetic health problems in females are as follows:

  • Chromosomal aneuploidy in expecting moms' babies: A circumstance in which a cell's chromosomal number is wrong. If a mistake is made during the normal fertilization process, the number or structure of chromosomes might vary, resulting in an offspring with birth abnormalities due to the atypical structure or number. This is a state in women health issues where one should be careful about. 

The most prevalent type of abnormality is trisomy 21, sometimes known as Down syndrome, which is caused by an extra chromosome 21. These alterations in the fetal condition can be detected via genetic disorder screening and diagnostic testing, as well as pre- and post-test counseling. These include noninvasive screening tests such as NIPT and parental karyotypes, as well as invasive diagnostic procedures.

  • X-linked hereditary illnesses: Certain disorders are X-linked, which indicates that a female with two X chromosomes will be a carrier, but her male offspring will be affected because men only receive one X chromosome from their mother and one Y chromosome from their father. Knowing if you're a carrier before you get pregnant can help you plan genetic counseling. Testing is offered for illnesses such as Fragile X, Hemophilia, and Duchenne Muscular Dystrophy, among others.
  • Screening for hematological disorders: Couples must be tested to see if they are carriers for hematological disorders including thalassemia and sickle cell disease. Consanguinity raises the chances of inheriting a recessive genetic condition by about 25%.

A carrier screening test can assist avoid the transmission of both X-linked and thalassemia and sickle cell anemia. It also aids couples in better understanding and planning for their future. This is a comprehensive test screening that can identify disease-causing mutations in over 2,000 genes.

Also Read: List Of Diseases That Might Develop Due To Genes 

  • Recurrent pregnancy loss (RPL): it is characterized as three or more consecutive pregnancy losses before the 20th week after the last menstrual period. RPL affects 1% to 2% of pregnant women, according to epidemiological research. Recurrent pregnancy losses are caused by genetic health problems in roughly 2-5 percent of cases. The majority of cases of pregnancy losses are caused by chromosomal or genetic disorders. The oddity could have been caused by an early embryo, egg, or sperm.

There are genetic tests that can assist in determining if the pregnancy loss was caused by an incorrect number of chromosomes, as well as provide information on how to plan and support a future pregnancy.

  • Hereditary breast and ovarian cancer: Mutations in the BRCA1 and BRCA2 genes cause around 15% of all ovarian cancers and 7% of all breast cancers in women. We now have predictive testing for this, such as BRCA1 and BRCA2 gene tests. Not only may early detection save lives, but it can also save money on advanced treatment.

Bottom Line

Women have been shown to live longer than men. According to the World Health Organization, women have a life expectancy of 74.2 years, while males usually have a life expectancy of 69.8 years (WHO). Women, on the other hand, consume more health services, have more disabilities, and have less social protection. Similarly, some disorders are unique to women health issues and are associated with female organs.

Genetic health problems, in addition to these, impact women health issues differently. Women are more likely than men to get them at a younger age. In fact, women and men may have different symptoms and, as a result, require different treatments for the same disease.



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