Levitra is an oral therapy for the treatment of one of the most common sexual dysfunctions in men, erectile dysfunction. It is a monohydrochloride salt of vardenafil and a selective inhibitor of phosphodiesterase type 5.
Various studies have shown the benefits of phosphodiesterase type 5 inhibitors for the treatment of erectile dysfunction. Erectile dysfunction is defined as a condition in which getting a firm penile erection is a questionable aspect for a man. Increased age is the most significant cause of erectile dysfunction, but it can also result from health or emotional problems or from both. Reduced blood flow or any harm to the nerves in the penis can result in the problems with erections, and it can be caused by high blood sugar level, high blood pressure, heart disease, smoking, and consumption of alcohol. Emotional problems such as depression, stress, or worry can also lead to the development of erectile dysfunction.
How does Levitra work?
Vardenafil, which is an active medical ingredient present in Levitra, produces significant and clinically meaningful improvement in all the parameters of the erectile function. It is considered to be a strong PDE 5 inhibitor that has been shown to be highly efficacious in men who have erectile dysfunction. This drug is well tolerated and is believed to be associated with rapid and reliable treatment response.
In order to understand the functioning of Levitra on erectile dysfunction, it is important to understand how an erection is achieved. Penile erection is a process that is initiated by the relaxation of smooth muscles in the erectile tissue. During sexual stimulation, nitric oxide is released into the erectile tissue, which increases the synthesis of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells. cGMP causes the smooth muscle relaxation and leads to increased blood flow in the penis. cGMP plays a vital role in penile erection. Levitra inhibits the enzyme which is responsible for the degradation of cyclic guanosine monophosphate, and these enzymes are known as phosphodiesterase type 5 or PDE5. During sexual stimulation, when the nitric oxide in released these enzymes inactivates cGMP in the cytoplasm. Levitra inhibits the enzymes, and this inhibition, in turn, increases the concentration of cGMP that enhances smooth muscle relaxation and causes a penile erection that is firm enough to have satisfactory sexual intercourse.
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Can other medications affect Levitra?
Yes, there are certain medications that are known to interact with Levitra such as nitrates, ketoconazole or itraconazole, ritonavir, erythromycin, alpha-blockers, and other medicines that treat erectile dysfunction. Take Levitra exactly as the doctor prescribes and do not take more than one dose in a day.
Do not take this drug without consulting a doctor as there are medicines that interact with this drug, and the only doctor can guide you completely about the complications and benefits that are associated with this drug. Also, do not forget to share your medical history and the list of all the medications you are currently taking. Before taking Levitra, always tell your doctor about medical problems such as:
- Have high or low blood pressure
- Have had a stroke
- Have stomach ulcers
- Have had an erection that lasted for more than 4 hours
- Have deformed penis shape
- Have hearing problems
- Have problems with blood cells such as sickle cell anemia
What are the side effects of Levitra?
Levitra is a well-tolerated drug and does not necessarily cause side effects, but some of the common side effects that you might experience after taking this drug are:
- Nasal congestion
- Upset stomach
- Back pain
Generally, these side effects are mild to moderate, but if you experience any serious side effect, get in touch with your doctor immediately to avoid any future complications.