What is Nobegliz M 60 XR

Nobegliz M 60 XR Tablet is an oral antidiabetic medication manufactured by Mankind Pharma Ltd. It combines two FDA-approved active salts, Gliclazide (a Sulfonylurea) and Metformin (a Biguanide). It is used to treat patients, particularly adults, with Type 2 Diabetes Mellitus.

Gliclazide helps the pancreas release more insulin, while Metformin lowers glucose production in the liver, slows down its absorption in the intestines, and enhances the body's response to insulin. This combination works well to manage blood glucose levels in Type 2 Diabetes Mellitus patients (adults), especially when lifestyle changes like diet, exercise, and weight loss aren't enough.

Some of the common side effects include nausea, vomiting, and diarrhea. One may also experience low blood sugar levels (Hypoglycemia) if it is taken alongside other antidiabetic medications. Alcohol consumption should be avoided while taking the drug, as it may cause Hypoglycemia as well as Lactic Acidosis in some cases. Other significant interactions include diseases like kidney and liver disease.

It is essential to continue taking the medication unless the doctor recommends otherwise. The medication is only part of the treatment of Type 2 Diabetes Mellitus. Having a healthy lifestyle with a balanced diet and regular exercise per the doctor's instructions is crucial for long-term better Diabetes management.

What are the benefits of taking Novegliz M 60 XR

The combination of Glicazide and Metformin in the medication provides multiple benefits to patients with Type 2 Diabetes Mellitus.

• It helps reduce and stabilize blood glucose levels by increasing insulin release from the pancreas, reducing the liver's glucose production, and improving insulin sensitivity.
• By maintaining better glycemic control, this medicine helps lower the risk of serious Diabetes-related complications such as kidney damage, nerve problems, vision loss, diabetic foot, heart attack, and stroke.
• The combination of two different classes of antidiabetic agents provides a broader approach to managing type 2 Diabetes Mellitus, making it more effective than single-drug therapy in many cases.
• Using a combination tablet reduces the need for multiple pills, making it easier to stick to the treatment and maintain consistent blood sugar control.

How to take Nobegliz M 60 XR

Nobegliz M 60 XR is a prescription-based medication that patients should take according to their doctor's recommendations. Here are some general guidelines for this medication.

• Take the dose as per the doctor's instructions.
• Take the medicine once daily at a fixed time.
• Swallow the whole tablet with water. Do not crush, chew, or break it.
• Take it with food.

Strengths and Substitutes

No strengths and substitutes of Nobegliz M 60 XR are available at Cheap Medicine Shop.

What are the side effects of Nobegliz M 60 XR

It is generally a well-tolerated medication. However, like any other antidiabetics, it can cause some side effects.

• Low blood sugar (Hypoglycemia)
• Nausea
• Vomiting
• Diarrhea
• Stomach pain
• Constipation
• Headache

They are temporary and will disappear in due time. However, if the symptoms continue or worsen, consult a doctor immediately.

Safety Advice

Liver disease

Patients with liver disease should take the medication cautiously. For those with mild to moderate liver issues, doctors may prescribe a lower dose and monitor liver function closely. However, it is not advised for individuals with severe liver disease due to a higher risk of serious side effects like Lactic Acidosis.

Kidney impairment

Patients with kidney impairment should use the medication cautiously. It is not recommended for those with severe kidney disease, as Gliclazide and Metformin are mainly eliminated through the kidneys. Reduced kidney function can raise the risk of serious side effects, particularly Lactic Acidosis.

Pregnancy and breastfeeding

It is unsafe for pregnant women to take the medication. The combination of Gliclazide and Metformin can potentially harm the baby. Consult a doctor, as they will give appropriate medication for the condition. Similarly, studies have shown that the drug is excreted into the milk. Consult a doctor for appropriate medication.

Avoid

Avoid taking the medication if you are allergic to Gliclazide and Metformin. Alcohol may affect blood sugar levels, causing Hypoglycemia, and patients should avoid it. Due to fluctuations in blood sugar levels, driving may also be affected.