Forxiga 10mg Tablet
| Pack Size | Price | Qty | Unit Price |
|---|---|---|---|
| 28 Tablet/s | $41.55 | $1.48 | |
| 56 Tablet/s | $78.95 | $1.41 | |
| 84 Tablet/s | $112.19 | $1.34 |
What is Forxiga 10mg
Forxiga 10mg is an oral antidiabetic medication primarily used to treat Type 2 Diabetes Mellitus in adults when diet and exercise alone fail to provide adequate glycemic control. Its active ingredient is Dapagliflozin (10mg), which belongs to the sodium-glucose co-transporter 2 (SGLT2) inhibitor class of medications.
This medicine works by helping the kidneys remove excess sugar from the body through urine, effectively lowering blood glucose levels. AstraZeneca is the leading manufacturer of Forxiga 10mg.
This medication also provides significant benefits for people with heart failure with reduced ejection fraction and chronic kidney disease, regardless of Diabetes status. Common side effects include genital yeast infections, urinary tract infections, and increased urination frequency.
Store Forxiga 10mg in original packaging at room temperature below 30°C, away from moisture and direct sunlight. Patients with severe kidney impairment, type 1 Diabetes, Diabetic Ketoacidosis, or those on dialysis should avoid this medication.
Pregnant and breastfeeding women should not use Forxiga without medical supervision due to potential fetal and infant risks.
What are the benefits of Forxiga 10mg
Forxiga 10mg functions by selectively inhibiting SGLT2 proteins located in the proximal tubules of the kidneys. These proteins normally reabsorb approximately 90% of filtered glucose back into circulation. By blocking SGLT2, Forxiga increases urinary glucose excretion, reducing plasma glucose levels independently of Insulin action and preserving pancreatic beta-cell function.
Key benefits of Forxiga 10mg include:
- Significant reduction in HbA1c levels.
- Promotes weight loss through caloric loss via glucosuria.
- Reduces systolic blood pressure by 2-5 mmHg.
- Decreases the possibility of cardiovascular death and hospitalization for heart failure.
- Slows the progression of chronic kidney disease.
- Low risk of Hypoglycemia when used as monotherapy.
Notably, Forxiga 10 is most effective with lifestyle modifications, including proper diet and regular physical activity.
How to take Forxiga 10mg
Forxiga 10 is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:
- Take Forxiga 10 once daily at any time of day, preferably at the same time each day.
- Swallow the tablet whole with water.
- Take with or without food.
- Do not exceed one 10mg tablet daily unless specifically directed by your healthcare provider.
Strengths and substitutes
The strengths and substitutes available for Forxiga at Cheap Medicine Shop are:
| Product name | Unit price |
| Oxra 10 Mg Tablet | $19.00/10 tablets |
| Forxiga 5mg tablet | $12.70/10 tablets |
What are the side effects of Forxiga 10mg
Forxiga 10 is generally well-tolerated with a favorable safety profile. However, it may cause side effects, including:
- Genital mycotic infections (more common in women)
- Urinary Tract Infections
- Increased urination
- Volume depletion symptoms (dizziness, hypotension)
- Back pain
These adverse effects typically resolve as your body adjusts to the medication and rarely require treatment discontinuation. However, seek immediate medical attention if you experience severe abdominal pain, difficulty breathing, unusual fatigue, or signs of serious genital or urinary tract infections.
Safety Advice
Forxiga 10 can be safely used in patients with mild to moderate liver impairment without dose adjustment. However, patients with severe hepatic dysfunction should use this medicine cautiously under medical supervision. Regular liver enzyme monitoring may be recommended in patients with existing liver conditions. Always consult a doctor before use.
Forxiga's glucose-lowering efficacy diminishes with declining kidney function. It is not recommended for those with moderate to severe kidney impairment for Diabetes treatment. However, it may still be prescribed for heart failure or kidney disease indications with careful monitoring and dose considerations.
Forxiga 10 is contraindicated during pregnancy, particularly in the second and third trimesters, due to potential adverse effects on fetal kidney development observed in animal studies. Women planning pregnancy should discuss alternative treatments. Breastfeeding mothers should avoid Forxiga as Dapagliflozin may be excreted in breast milk, affecting infant kidney development.
Alcohol with metformin can raise the risk of dehydration and lactic acidosis. Excessive heat exposure also increases the risk of dehydration and may affect medication stability. Loop diuretics without supervision can worsen fluid loss, while Insulin or sulfonylureas without dose adjustment raise the risk of Hypoglycemia. Ketogenic diets may increase the chance of Diabetic Ketoacidosis.
Frequently Asked Questions (FAQs)
What is the best time to take Forxiga 10mg?
Forxiga 10 can be taken at any time of day, with or without food. Many patients prefer morning dosing to avoid nighttime urination. Choose a consistent time daily for optimal effectiveness and easier adherence.
How long does it take for Forxiga 10mg to start working?
Blood glucose improvements typically begin within 1-2 weeks of starting Forxiga 10. Maximum glucose-lowering effects are usually achieved within 4-6 weeks. Cardiovascular and kidney benefits develop gradually over months of continuous treatment.
Can Forxiga 10mg be taken with other Diabetes medications?
Yes, Forxiga 10 can be combined with metformin, sulfonylureas, or Insulin . However, doses of Insulin or sulfonylureas may need reduction to prevent Hypoglycemia. Always consult your doctor before combining Diabetes medications.
Will Forxiga 10mg cause frequent urination permanently?
No, increased urination is most noticeable during the first few weeks of treatment and typically becomes less bothersome as your body adjusts. The effect continues but becomes more manageable with time and proper hydration.
Should I stop Forxiga 10 if I get sick with vomiting or diarrhea?
Contact the doctor immediately if you experience persistent vomiting, diarrhea, or signs of dehydration while taking Forxiga 10. Temporary discontinuation may be necessary during acute illness to prevent complications like Diabetic Ketoacidosis.
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