Oxra 10 Mg Tablet

What is Oxra 10

Oxra 10 is a Sodium-glucose co-transporter 2 (SGLT2) inhibitor primarily prescribed to treat Type 2 Diabetes mellitus in adults. Its active ingredient is Dapagliflozin, which belongs to a class of medicines that help lower blood sugar levels by causing the kidneys to remove excess sugar from the body through urine.

It may be used as monotherapy or in combination with other antidiabetic medications when diet and exercise do not provide adequate glycemic control. Sun Pharmaceutical Industries Ltd. is the renowned manufacturer of Oxra 10, ensuring consistent quality and efficacy in each tablet. Each film-coated tablet contains 10 mg of Dapagliflozin (as propanediol monohydrate).

Common side effects of Oxra tablets include urinary tract infections, genital mycotic infections, and increased urination. Store these Dapagliflozin tablets in a cool, dry place below 30°C, away from moisture and sunlight. Keep out of reach of children. The medicine is not recommended for those with Type 1 Diabetes or diabetic ketoacidosis. It should be used with caution in patients with kidney impairment.

What are the benefits of Oxra 10

Oxra 10 mg works by inhibiting the Sodium-glucose co-transporter 2 (SGLT2) in the proximal renal tubules of the kidneys. This prevents glucose and sodium reabsorption, leading to increased urinary glucose excretion as well as reduced blood glucose levels, independent of insulin action. This unique mechanism helps address the underlying pathophysiology of Type 2 Diabetes.

The benefits of Oxra tablets include:

• Effective reduction of HbA1c levels
• Weight loss
• Reduction in systolic blood pressure
• Low risk of Hypoglycemia when used as monotherapy
• Favorable effects on cardiovascular outcomes
• Once-daily oral dosing for better compliance

It is crucial to note that Oxra should be part of a comprehensive treatment plan that includes diet and exercise for optimal Diabetes management.

How to take Oxra 10

Oxra 10 mg is a prescription medication that should be taken per your doctor's instructions. Here are the general guidelines:

• Take Oxra 10 mg once daily at any time of the day.
• Swallow the tablet whole with a glass of water. Do not crush, chew, or break the film-coated tablets.
• Take it with or without food.
• Maintain adequate fluid intake to reduce the risk of volume depletion. Do not exceed the 10 mg dose unless prescribed.

Strengths and substitutes

Currently, there are no strengths and substitutes available for Oxra at Cheap Medicine Shop.

What are the side effects of Oxra 10

Oxra tablets are generally well-tolerated by most patients. However, it may cause side effects, including:

• Genital mycotic infections (thrush)
• Urinary Tract Infections
• Increased urination
• Volume depletion (dehydration) and Hypotension

These adverse effects typically do not require treatment discontinuation but should be monitored. Maintaining good personal hygiene and adequate hydration can help prevent or minimize some of these side effects.

Safety Advice

Liver disease

People with mild to moderate liver impairment do not require dosage adjustment of Oxra. However, for those with severe hepatic impairment, a starting dose of 5 mg is recommended, with possible titration to 10 mg if well-tolerated. Regular liver function tests are advised during treatment. Always consult your doctor.

Kidney impairment

Oxra does not require dosage adjustment for patients with mild kidney impairment. It is not recommended for those with moderate to severe renal impairment (eGFR < 45 ml/min/1.73 m²) or end-stage renal disease. Regular monitoring of kidney function is essential throughout treatment. Consult a doctor before use.

Pregnant and breastfeeding women

Oxra is not recommended during pregnancy as there is limited data on its use in pregnant women. Animal studies have depicted reproductive toxicity at high doses. It should be discontinued during pregnancy. It is unknown whether Dapagliflozin passes into breast milk, but due to potential risks to the newborn/infant, Dapagliflozin is not recommended during breastfeeding.

Avoid

Avoid alcohol as it may increase the risk of Hypoglycemia. Do not opt for low-carbohydrate diets or fasting, which may increase the risk of Ketoacidosis. Also, avoid medications that can impair kidney function, such as NSAIDs. Do not use diuretics without appropriate dosage adjustment, as they may increase the risk of dehydration, and insulin or insulin secretagogues (like sulfonylureas) without appropriate dose adjustment due to increased Hypoglycemia risk.