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Chronic Kidney Disease: Symptoms and Treatment

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If someone suffers from Chronic Kidney Disease or CKD, the kidneys are damaged and cannot filter blood the way they should.

The kidneys are among the essential organ of the human body. Kidneys are located just below the liver and consist of around 11 lakh nephrons responsible for the blood’s filtration process. Kidneys are also called the functional units of the body.

In addition, the kidneys are responsible for maintaining various nutrients, vitamins, and minerals in the body, like sodium and potassium.

 The kidney helps regulate vitamin D, which promotes the generation and development of red blood cells in the body. Diseases like obesity, hypertension, and diabetes damage the nephrons in the kidney. Deteriorating the critical functioning of the kidney in the body increases the risk factors of CKD. Chronic renal disease is another name for CKD or Chronic Kidney Disease.

Chronic Kidney Disease and Its Symptoms:

Signs and symptoms of Chronic Kidney Disease(CKD) develop over time if kidney damage progresses slowly. In chronic kidney disease, the kidneys are first swollen and then shrink to a smaller version. Loss of kidney functionality can cause a build-up of fluid or protein in the urine that is severely harmful to the kidneys.

Chronic renal disease patients have these symptoms:

  • Nausea
  • Vomiting
  • Anaemia
  • Loss of appetite
  • Fatigue and weakness
  • Sleep problems
  • Frequent urination, especially at night
  • Decreased mental sharpness
  • Muscles cramps
  • Swelling of feet and ankles
  • Dry and itchy skin
  • High blood pressure that’s difficult to control
  • Shortness of breathing if fluid builds up in the lungs
  • Chest pain if fluid builds up around the lining of the heart
  • Dark urine in some cases

What are the 3 Common Causes of Chronic Kidney Disease?

Renal kidney disease occurs when a disease or condition impairs kidney damage, causing kidney damage to worsen over some time. As a result, the damaged kidney cannot adequately filter blood. As a result, it loses its function to remove waste from the body, causing the excess fluid and waste from the blood to remain in the body.

The three common causes of chronic renal disease are:

  • Diabetes: The unmanaged blood sugar levels cause immense damage to the kidneys.
  • High Blood Pressure: Poor high blood pressure is a leading cause of chronic renal disease.
  • Polycystic kidney disease is a genetic disorder affecting the kidneys. It causes cysts to develop within your kidneys.

Cure for Kidney Disease

Chronic kidney disease is a disease that involves the gradual loss of kidney function. It seems not to show any signs of its occurrence in the first stage, but there is an increase in blood, urea, and serum creatinine.

With the help of medicines and conventional dialysis, the infection in the kidney is treatable. Practising proper meals and medications can restrain but can not entirely cure. The kidney failure uncertainty increases when the level of urea and creatinine rises.

Chronic Kidney Disease Treatments:

Treatment for CKD focuses on decelerating the progression of kidney damage by controlling the cause. Damage to a person’s kidney from CKD is usually permanent. However, some therapies can help prevent the symptoms, reduce the risks of complications and slow the condition’s progression.

 The kidney has two kinds of disease. The initial one is an acute kidney disease that occurs without any symptoms. In this unit functioning of each kidney is delinquent at a very swift pace. Severe kidney disease is curable if detected and treated by doctors on time.

1. Through Medicine

Medicines and dialysis can help a person undergoing Chronic Kidney Disease. If the kidney fails, then the last alternative is a kidney transplant. At the stage of chronic renal malfunction, the patient must undergo hemodialysis. In this method, the blood is cleaned three times a week and twelve times a month. Some of the renowned generic and branded medicines include Votrient 400(Pazopanib Hydrochloride), Nexavar 200(Sorafenib Tosylate), Sorafenat 200 (Bevacizumab)

2. Treatment by Dialysis

Usually, dialysis is performed when the chronic renal disease is at a firm pace. In this, a machine circulates the patient’s blood. The intoxicating substances are discharged within this process, and purified blood is obtained in an individual’s body. In addition, dialysis is performed two to three times a week. This utilizes an absolute time of four hours. As per the patient’s requirement, this level may increase or decrease.

3. Treatment by Cross-matching

After complete kidney failure, a kidney transplant is the only remaining option. However, it requires the blood of a relative, which is suitable for a patient. If the blood of the donor and the patient do not match, then doctors have to perform a cross-transplant.

4. Treatment by ABO

If a suitable donor of the same blood group is not available, the ABO(blood group) incompetent kidney implantation process is applied. In addition, the antibodies present in the blood group are removed. Therefore, after the implantation treatment, the patient body can easily accept the donor’s kidney.

5. Treatment by Robotic Transplant

Under the Laparoscopic Kidney Implantation process, a kidney is taken out through a small hole, and through open surgery, the kidney is transplanted inside the body. Both the patient and the donor do not undergo any suffering during the whole process.

Blood urea, serum creatinine, serum electrolyte, and kidney function tests can help detect CKD.


Chronic renal disease is a widespread condition that affects around 1 in 7 adults in the U.S. It is more likely to affect African Americans, Asian Americans and Native Americans than white people. If there is a history of chronic renal disease in the family, other family members must take proper preventive measures for the kidney’s well-being. 

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Photo of author Janet Fudge
Janet Fudge is a highly skilled and experienced pharmacologist who serves as a contributing writer for With a strong academic background from a premier US University and a passion for helping others, Janet has become a trusted voice in the pharmaceutical world. After completing her Doctor of Pharmacy degree, Janet embarked on a successful career in the pharmaceutical industry, working with various clients, including hospitals, retail pharmacies, and drug manufacturers. Her in-depth knowledge of pharmacology and dedication to patient-centered care has led her to excel in her field. As a writer for, Janet uses her wealth of expertise to provide readers with accurate, reliable, and up-to-date information on various topics related to medicine and healthcare. Her engaging writing style and ability to break down complex topics into easily digestible content make her a valuable resource for healthcare professionals and the general public.
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