US Toll Free Call/Text:
+1(888) 866-7566
Int. No Call/Text:
+1(718) 301-8411

Is Sildenafil a Performance Enhancing Drug?

Photo of author

Sildenafil, or generic Viagra, is a popular medicine for Erectile Dysfunction (ED). Is Sildenafil a Performance Enhancing Drug?

It is among the first medicines to get FDA approval for treating ED.

ED is an inability in men and assigned males at birth (AMAB) to get or hold erections.

But Sildenafil is often taken off-label by people with Benign Prostate Hyperplasia (BPH). 

Similarly, Sildenafil may have other uses but is not medically approved for them. 

One such benefit might be its use as an enhancement drug. 

In this article, we will outline if Sildenafil is effective as an enhancement drug. 

Also, we will discuss the pros and cons of taking Sildenafil for other uses.

Is Sildenafil a performance enhancing drug?


Sildenafil is a popular ED medicine that may increase blood flow.

According to a BMJ journal study, Sildenafil is not known to enhance one’s performance.

Sildenafil can help you get an erection but does not increase your time in bed. 

It means that Sildenafil won’t help if you have problems ejaculating early.

FDA approves Sildenafil only for treating ED and PAH. 

It does not recommend Sildenafil for other uses, including Premature Ejaculation. 

Sildenafil is available as Viagra for ED in men or AMAB.

Whereas Revatio is the brand name of Sildenafil for treating Pulmonary Arterial Hypertension.

What is Sildenafil?

What is Sildenafil?Source: Getty-images
What is Sildenafil?

Sildenafil is the active ingredient in the brand and generic Viagra. 

Sildenafil belongs to the class of drugs called Phosphodiesterase-5 (PDE5) inhibitors.

According to, Sildenafil was first made to treat people with heart problems like high blood pressure and Angina.

Later, scientists found that Sildenafil helped people get better erections.

It led to the introduction of Viagra for treating ED in 1998. 

Viagra is the first-line treatment for ED in men and AMAB. 

Later in 2005, the FDA approved Sildenafil for Pulmonary Arterial Hypertension (PAH).

It is marketed as the brand Revatio to treat people with PAH. 

This is how Sildenafil was put to use for ED and PAH.

How does Sildenafil work?

Sildenafil belongs to a class of Phosphodiesterase (PDE5) inhibitors. 

It acts by blocking the working of the PDE5 enzyme in the penis. 

This enzyme controls the penile blood flow, making it difficult to get an erection. 

Now let’s discuss if this action can help enhance one’s physical performance. 

According to Medline Plus Sildenafil’s action widens blood vessels in the arteries. 

It helps in increasing blood flow through the heart. 

This action works even at places higher than sea level.

At higher altitudes, the oxygen content in the air reduces. 

It is why your lungs cannot breathe enough oxygen.

Sildenafil dilates the blood vessels in the heart, boosting blood flow through them.

Higher blood flow enables more oxygen to pass through your lungs.

This action improves oxygen supply throughout one’s body.

A study indicates that improved blood flow allows a person to become physically active. 

This is how Sildenafil promotes overall physical activeness, not specifically of the penis. 

Despite Sildenafil’s ability to provide such amazing results, remember it is a prescription medicine. 

Hence, do not take Sildenafil without first consulting a doctor.

Who can take Sildenafil safely?

Who can take Sildenafil safely?Source: studioroman
a question for man

One needs to consider some caution before taking Sildenafil.

Here is what you should keep in mind:

You can take Sildenafil if you fulfill all the conditions mentioned below:

  • A man or an AMAB 
  • Experience erection problems
  • Discussed your symptoms with a doctor
  • Disclosed your medical history to the doctor
  • The doctor prescribed Sildenafil for your ED 

It is essential to follow these safety precautions

If you skip these cautions, taking Sildenafil may be unsafe.

If you buy Sildenafil or other ED medicines from a source that isn’t reliable, you’re more likely to have side effects.
Always buy medicines from reliable pharmacies like Cheap Medicine Shop.

Risks of taking Sildenafil off-label

The FDA only approves Sildenafil for treating ED and BPH in men or AMAB. 

Sometimes the doctor may prescribe it off-label for other purposes.

These include Hypertension and other cardiovascular conditions. 

According to WebMD, your doctor may also recommend Sildenafil for BPH.

But taking Sildenafil for other purposes is not entirely safe. 

Most medicines have some side effects, and Sildenafil is no different. 

Sildenafil may have common to rare side effects, including:

  • Headache
  • Flushing
  • Nausea
  • Indigestion
  • Dizziness
  • Runny nose
  • Priapism
  • Muscle or body pain.

If your condition worsens, seek medical help.

Key Takeaways

Sildenafil is an FDA-approved medication for treating ED.

It helps to boost blood flow throughout one’s body. 

For the same reason, it can offer several ofter benefits. 

Although not backed medically, one may use it to enhance physical performance. 

But as with most medicines, Sildenafil may have some side effects. 

Consult your doctor about how to use it for the best results.

Off-label use is the term for using a legal drug in a way that isn’t on the label.
Phosphodiesterase-5 (PDE5) inhibitors are medicines that regulate the action of the PDE5 enzyme in the penis.
Citations: Cheap Medicine Shop only refers to credible, authoritative sources for our content. If you’re curious about how we ensure the integrity of our content, we encourage you to read our Content Information Policy.

How useful was this post?

Click on a star to rate it!

Average rating 4.2 / 5. Vote count: 193

No votes so far! Be the first to rate this post.

Photo of author Janet Fudge
Jim Carson is a highly skilled and dedicated medical writer passionate about advancing medical practice. With years of experience in the field of medical sciences, Jim has made significant contributions to various studies aimed at improving healthcare outcomes. He currently writes for, providing expert insights and knowledge on various topics. Jim's expertise extends to various areas, including drug interactions, dosages, side effects, and best practices for medication use. In Los Angeles, Jim lives with his loving wife, children, and beloved pets. He deeply values spending time with his family and cherishes their presence. When he's not writing, Jim enjoys watching football games and staying updated with the latest sports news. Jim's writing shines through his commitment to advancing medical practice and improving healthcare outcomes. Readers can trust Jim's articles to be informative, accurate, and reliable, making him a trusted pharmaceutical information source for the website's audience.
Please enable JavaScript in your browser to complete this form.

We’d Love To help

Reach out to us we will get back to you

Preferable Time