Erectile Dysfunction (ED) or impotence is a common sexual problem affecting millions of men worldwide. If you have ED, don’t worry, as it is treatable. With available treatment options, such as Tadalafil and Sildenafil, you can choose ED pills to improve your erections and enhance confidence. So, which is better, Tadalafil vs Sildenafil?
When comparing Tadalafil and Sildenafil, both are FDA-approved medications and have similar mechanisms of action. The differences lie in their duration of action, approved uses, unique side effects, doses, and dosing options.
This article will discuss the differences between Sildenafil and Tadalafil based on their side effects, precautions, and prices. It will also help you decide which is better, Sildenafil or Tadalafil.
Tadalafil vs Sildenafil Citrate: Overview
The table below discusses the similarities and key differences between the two most potent Erectile Dysfunction pills, Tadalafil vs Sildenafil:
| Aspects | Tadalafil | Sildenafil |
|---|---|---|
| Brand name | Cialis and Adcirca | Viagra and Revatio |
| Approved uses | Erectile Dysfunction, Pulmonary Arterial Hypertension (PAH), and Benign Prostatic Hyperplasia (BPH) | Erectile Dysfunction and Pulmonary Arterial Hypertension |
| Appearance | Yellow pill | Blue pill |
| Dosage | 2.5 mg, 5 mg, 10 mg and 20 mg | 25 mg, 50 mg, and 100 mg |
| Onset of action | Within 30-60 minutes | Within 30-60 minutes |
| Duration of action | 36 hours | 4-5 hours |
| Dosing options | Daily or as needed | As-needed only |
| Legal manufacturer | Eli Lilly Company | Pfizer |
| Preferred for | Long-lasting effects | Short-term usage |
| Unique side effects | Muscle or back pain | Vision changes and increased sensitivity to light |
Sildenafil vs Tadalafil: Key differences
Sildenafil (Blue Pill) and Tadalafil are prescription generic medications primarily used to treat ED in men and PAH. Both belong to the Phosphodiesterase Type 5 (PDE5) inhibitors class of medicines, which increases blood flow to the penis and have treated millions of men worldwide.
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Now, we will discuss certain differences between Sildenafil and Tadalafil that will help you decide which will work best for you, such as:
1. Brand name and legal manufacturer
Sildenafil Citrate is known under the brand name Viagra. Pfizer is the legal manufacturer of Viagra. However, once their patent expired, many companies manufactured and sold Viagra as a generic option, such as Cenforce 200 mg.
On the other hand, Tadalafil is sold under the brand name Cialis. Eli Lilly is the manufacturer of Cialis. Since their patent expired, many companies have manufactured and sold Tadalafil, such as Vidalista 20 mg, at affordable prices.
2. Approved uses
One of the differences between Sildenafil and Tadalafil is their approved uses. Tadalafil is used for treating Erectile Dysfunction, Pulmonary Arterial Hypertension, and Benign Prostatic Hyperplasia or enlarged prostate. Unlike Tadalafil, the blue pill treats ED in men and PAH in both men and women.
Therefore, while Sildenafil can be a first option for people dealing with ED and Lungs Hypertension, men struggling with BPH can make Tadalafil their first choice.
3. Onset of action
One of the differences between Tadalafil vs Sildenafil is their onset of action and peak plasma concentration levels (peak results). Both Tadalafil and Sildenafil start working within 30-60 minutes.
The blue pill has shown peak plasma concentration within 30-120 minutes (the median time is 60 minutes) after taking the prescribed dose. In contrast, Tadalafil may take up to two hours to show peak results. Therefore, based on rapid action, you may prefer Sildenafil over Tadalafil.
4. Duration of action
Regarding the duration of action, Tadalafil lasts 36 hours. On the contrary, Sildenafil keeps the window to engage in sexual intercourse open for up to 4-5 hours. Thus, if you prefer to keep the opportunity available for a prolonged duration, Tadalafil can be a suitable option.
5. Dosage and dosing options
Sildenafil is commonly prescribed in doses ranging from 25 mg to 100 mg. In contrast, Tadalafil is usually prescribed in four doses: 2.5 mg, 5 mg, 10 mg, and 20 mg. The usual prescribed dose for ED is 10 mg, 2.5 mg, or 5 mg for BPH treatment and 40 mg (2 pills of 20 mg) for PAH treatment.
While Sildenafil is used as a needed medicine for ED treatment, Tadalafil can be used daily or as needed, depending on the condition for which you use it. However, it is advisable to use this medicine in the prescribed dosage and as directed by your doctor to treat PAH and BPH symptoms.
6. Side effects comparison
Both drugs share common side effects, such as headaches, flushing, nasal congestion, indigestion, and dizziness. Still, some unique side effects can help you decide which works best for you.
- Tadalafil: Tadalafil is likely to cause muscle or back pain due to its prolonged action.
- Sildenafil: It is likely to cause temporary visual changes like blue tint or increased sensitivity to light in some people.
7. Interactions and precautions
Tadalafil and Sildenafil are likely to interact with certain medications, diseases, and food choices. You should always inform your doctor if you have an ongoing disease, take any medicine, or follow a specific dietary routine.
The table below discusses the interactions that are likely to happen in Sildenafil vs Tadalafil:
| Interactions | Tadalafil | Sildenafil |
|---|---|---|
| Medicine interaction | Nitrates, Alpha Blockers, PDE5 inhibitors, antidepressants, CYP3A4 inhibitors, inducers, and Guanylate Cyclase Stimulators (GCS), PDE5 pills | Nitrates, Alpha Blockers, antidepressants, CYP3A4 inhibitors and inducers, GCS, and PDE5 inhibitors |
| Disease interaction | Heart problems, Hypertension, Hypotension, pulmonary disease, kidney and liver disease | Cardiovascular disease, liver disease, seizure disorders, Sickle Cell Disease, bleeding disorders, kidney dysfunction, and visual disorders |
| Food interaction | Grapefruit and its juices, St John’s Wort | Grapefruit and its juices |
| Alcohol interaction | Avoid excessive alcohol intake | Avoid alcohol consumption |
| Can you drive | No | Yes |
These Erectile Dysfunction pills also have certain differences in their precautions, such as.
- You need to take Sildenafil without food. Avoid high-fat meal while taking Sildenafil. However, you can take Tadalafil with or without food.
- You should not drink alcohol while taking Sildenafil. However, mild alcohol (less than five shots) is generally safe with Tadalafil.
- Sildenafil is generally safe for people with liver disease, and no dosage adjustment is required for mild to moderate liver impairment. In contrast, the maximum dosage of Tadalafil in people with mild to moderate liver impairment is 10 mg, and it is not recommended in people with severe liver problems.
Furthermore, avoid taking these medications if you are allergic to Sildenafil or Tadalafil. Always inform your doctor before taking these medications if you are pregnant or breastfeeding. Moreover, it is not a contraceptive and does not protect you against STDs or pregnancy.
8. Price comparison
Sildenafil and Tadalafil are available in generic and brand versions. The cost may also depend on your doctor’s prescribed strength and quantity.
Generally, Tadalafil is slightly costlier than Sildenafil. However, you can purchase reliable ED medications from the Cheap Medicine Shop, which offers authentic medications at affordable prices.
Thus, based on the above points, you can determine which is better for you, Sildenafil or Tadalafil. However, before making any decision, always consult your doctor and seek prescribed medication for improved relief from erection issues.
Conclusion
So, are you still wondering what to choose between Tadalafil vs Sildenafil? Both medicines are FDA-approved and have similar actions and interactions. However, they have different strengths and dosing options.
Furthermore, they have similar onset of action but distinct duration. Tadalafil stays effective for 36 hours, which is quite powerful compared to Sildenafil.
Sildenafil may cause visual changes, and Tadalafil can lead to muscle or back pain as a unique side effect. Therefore, people prone to back pain may choose Sildenafil, and people with eye conditions may prioritize Tadalafil. Also, their different price may play a significant role in determining which is more suitable for you.
You can also consult your doctor and take the prescribed medicine and its dosage based on your condition.
Frequently Asked Questions
Which is better, Tadalafil or Sildenafil?
Tadalafil and Sildenafil are equally effective for Erectile Dysfunction, but Tadalafil offers a longer duration (up to 36 hours) and improved psychological outcomes. Sildenafil’s shorter duration (4–5 hours) suits those seeking immediate results. Both are safe, but choice depends on lifestyle needs and tolerance to side effects.
Can I take Sildenafil or Tadalafil without a doctor’s prescription?
No, Sildenafil and Tadalafil require a doctor’s prescription due to health risks and medicine interactions. Most regions, including the US, regulate these medications strictly and recommend taking them after a doctor’s prescription. Buy them from the Cheap Medicine Shop at the best prices.
Does Tadalafil or Sildenafil keep you hard after coming?
No, neither Tadalafil nor Sildenafil directly keeps you erect after ejaculation. These medications help you maintain erections during sexual arousal but do not prevent the natural loss of erection post-orgasm. However, Tadalafil’s more prolonged duration of action may allow for quicker recovery and additional erections within its 36-hour window.
Does either medication reverse ED?
No, Sildenafil and Tadalafil cannot reverse or cure ED. Both PDE5 inhibitors can temporarily improve penile blood flow and reduce erection problems. To cure ED, you need to find the condition’s underlying cause. Various physiological and psychological factors cause ED. Therefore, you should consult your doctor and seek treatment.
Can I take Sildenafil, Tadalafil, or Vardenafil 2 times a day?
No, you should never take Sildenafil, Tadalafil, or Vardenafil twice daily. They should not be taken more than once daily. Exceeding the recommended dose increases the risks of side effects like Priapism. Consult your doctor before altering dosage or frequency. Furthermore, avoid taking these medicines together to avoid side effects.
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