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Does Tadalafil Lower Blood Pressure: Understanding the Relationship Between Them

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Tadalafil is a widely used medicine for treating Erectile Dysfunction.

It is very effective for achieving an erection during sexual intercourse. The effects of Tadalafil can stay up to 36 hours.

It can interact with different medicines and health conditions. Tadalafil interactions must be kept in mind before consuming it.

But the critical question is can Tadalafil affect blood pressure? Does Tadalafil lower blood pressure? 

Let us move ahead to understand the relationship between Tadalafil and blood pressure.

Does Tadalafil lower blood pressure

Yes, Tadalafil can lower blood pressure due to the widening of the blood vessels.

Tadalafil is a PDE-5 inhibitor. It works by blocking the enzyme called PDE-5. 

When these enzymes are blocked, cGMP relaxes the smooth muscles and widens the blood vessels. This helps in increasing the blood flow to the penis and the other part of the body. 

Widening of blood vessels can cause an individual to experience a drop in blood pressure.

It is vital to know that the drop in blood pressure is minimal and temporary to adversely affect any individual.

Tadalafil is also used for treating Pulmonary Hypertension by lowering blood pressure in the lungs. As a result, the heart can pump blood throughout the body more efficiently.

Tadalafil is not recommended for individuals with low BP as it might further lower their BP.

How much blood pressure can be dropped by Tadalafil

Check blood pressureSource: 89stocker
Check blood pressure

As per the Cialis product label, a healthy person does not feel any effect from the drop in blood pressure.  

They experienced an average drop of 1.6 Hg in BP while lying down and 0.2 Hg in BP while standing.

However, individuals with low BP or any heart condition can get affected after taking Tadalafil due to lowering BP.

Individuals taking meds such as nitrates should avoid taking Tadalafil as it may further lower their blood pressure.

It can increase the side effects of low blood pressure, such as nausea, fatigue, and blurred or faded vision.

Your doctor may advise a lower dosage of Tadalafil if you are taking meds like Alpha-blockers.

Effects of taking Tadalafil with blood pressure medicines

Taking TadalafilSource: pixelshot
Taking Tadalafil

It is generally safe to consume Tadalafil with blood pressure medicines.

When Tadalafil is taken with BP meds such as Beta-blockers, it is unlikely to cause any harmful side effects.

However, it may temporarily lower the blood pressure. Healthy individuals aren’t affected by the decrease in BP due to the interaction between Tadalafil and these meds.

A person might experience some common side effects of low BP, such as-

  • Blurred or fading vision
  • Dizziness or lightheadedness
  • Fainting
  • Fatigue
  • Trouble concentrating
  • Nausea

Taking Tadalafil with Alpha-blockers or nitrates can further lower BP, causing extreme side effects such as

  • Confusion, especially in older people
  • Cold, clammy skin
  • Decrease in skin coloration (pallor)
  • Rapid, shallow breathing
  • Weak and rapid pulse
  • Dizziness

People with low blood pressure and other health conditions should avoid consuming Tadalafil with BP meds. 

Always consult your doctor before taking Tadalafil and antihypertensive drugs together. They might prescribe some other medication for managing symptoms of ED.


Tadalafil can help you in managing Erectile Dysfunction. 

By relaxing and widening blood vessels, Tadalafil improves blood flow and aids erections.

The answer to your question, does Tadalafil lower blood pressure is yes. The widening of blood vessels can cause blood pressure to drop a little. 

The drop is temporary and doesn’t affect a healthy individual. 

However, if you take high blood pressure meds such as Alpha blockers and have a pre-existing health condition, it can further lower your blood pressure.

Taking Tadalafil with BP meds may cause side effects such as fainting and nausea.  

Always consult your doctor before taking Tadalafil. They might suggest other ED medications, such as Sildenafil, for the treatment.

Frequently Asked Questions

Is Tadalafil used for high blood pressure?

Tadalafil is used for treating Pulmonary Hypertension (high BP in the lungs). It widens the blood vessel for easy blood flow and lowers blood pressure in the lungs.

Is Tadalafil safe for BP patients?

Yes, Tadalafil is generally safe for people with high blood pressure. However, you should avoid taking it with nitrates.

What medication should not be taken with Tadalafil?

You should avoid taking meds like nitrates, Bepridil, Acebutolol, and Nicardipine with Tadalafil. Consuming these medicines may further lower your blood pressure.  

Does Tadalafil cause high blood pressure?

Tadalafil does not cause High blood pressure. In fact, it is used for treating Pulmonary Hypertension. However, individuals with heart or liver conditions, low blood pressure, and chronic Hypertension should avoid Tadalafil. Consult a healthcare professional before taking Tadalafil.

Is Tadalafil safe for heart patients?

Tadalafil is not recommended for heart patients. It can interact with meds such as Alpha blockers and Nitrates which are used by heart patients. The interaction can cause to further lower blood pressure Talk with your doctor if you have cardiovascular disease. 

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Photo of author Janet Fudge
Jim Carson is a highly skilled and dedicated medical writer passionate about advancing medical practice. With years of experience in the field of medical sciences, Jim has made significant contributions to various studies aimed at improving healthcare outcomes. He currently writes for, providing expert insights and knowledge on various topics. Jim's expertise extends to various areas, including drug interactions, dosages, side effects, and best practices for medication use. In Los Angeles, Jim lives with his loving wife, children, and beloved pets. He deeply values spending time with his family and cherishes their presence. When he's not writing, Jim enjoys watching football games and staying updated with the latest sports news. Jim's writing shines through his commitment to advancing medical practice and improving healthcare outcomes. Readers can trust Jim's articles to be informative, accurate, and reliable, making him a trusted pharmaceutical information source for the website's audience.
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