If you have been searching online or talking to a doctor about Erectile Dysfunction (ED) treatment, you have likely come across both of these terms. And if you are confused about whether they are the same or different, you are not alone.
In fact, many men are unsure about which one to choose. Should you go for the well-known brand name Cialis or the more affordable generic version Tadalafil? Do they work the same way? Is Tadalafil as good as Cialis? What about side effects, and how long they last?
These are common questions—and they matter. Because choosing the right medication is not just about getting results—it is also about feeling safe, confident, and informed.
This article will explain everything you need to know about Cialis vs Tadalafil in simple, clear language and will help you make the right decision.
Cialis vs Tadalafil at a glance
The table below will help you understand the differences between Cialis and Tadalafil at a glance:
Feature | Cialis | Tadalafil |
Generic or brand | Brand | Generic |
Active ingredient | Tadalafil | Tadalafil |
Cost | Expensive | Less expensive |
Duration of action | Up to 36 hours | Up to 36 hours |
Onset of action | 30-60 minutes | 30-60 minutes |
Daily use option | Available | Available |
Shelf life | Longer due to brand quality | May vary depending on the manufacturer |
Use for BPH | Yes | Yes |
Side effects | Mild to moderate | Mild to moderate |
Brand vs Generic
Cialis is the brand name of the medicine, while Tadalafil is the generic version. Both contain the exact same active ingredient—Tadalafil—which treats ED.
Cialis was originally developed by a pharmaceutical company named Eli Lilly. Once their patent expired, other manufacturers were allowed to create generic versions using the same formula. These generics are sold under the name Tadalafil.
In simple terms, if Cialis is like a branded cola, then Tadalafil is like a store-brand cola. It has the same ingredients and same effects but without the brand name.
Active ingredient
Both Cialis and Tadalafil contain the same active ingredient, Tadalafil. This means that both medicines work the same way in the body. They belong to a group of medicines called Phosphodiesterase type 5 inhibitors (PDE5) inhibitors, which help increase the flow of blood to the penis region and help you get an erection.
So, when it comes to effectiveness, there’s no real difference between the two. As long as the Tadalafil you’re taking is made by a reliable manufacturer, it will work just like Cialis.
Cost
One of the biggest reasons people switch from Cialis to Tadalafil is cost. When making the Cialis vs Tadalafil price comparison, Cialis, being a brand name, is usually much more expensive.
Tadalafil is much cheaper—often costing just a fraction of the price. This makes it a cheaper option, especially for people who use it regularly. You should always purchase from reliable and trusted pharmacies like Cheap Medicine Shop.
Duration of action
One of the reasons Cialis became so popular is its long-lasting effect. Unlike other ED medicines that last only 4–6 hours, Cialis can last for 36 hours. That’s why it’s sometimes called ‘the weekend pill’.
Tadalafil, being the same medicine, also lasts up to 36 hours. This gives users more spontaneity and flexibility when it comes to intimacy. So, both Cialis and Tadalafil will give you same results.
Onset of action

Both Cialis and Tadalafil usually start working 30 to 60 minutes after taking the pill. However, this can vary from person to person, depending on age and metabolism. As per a report in the British Journal of Clinical Pharmacology (2005), food has no effects on the onset of Tadalafil.
It is best to take either pill at least 30 minutes before intimate activity for best results.
Daily use options
Cialis comes in the common strengths of 2.5 mg, 5 mg, and 10 mg. The lower strengths (2.5 mg and 5 mg) are often used for daily use, while the higher doses are for use as needed for ED treatment.
Tadalafil is also available in the same strengths, giving users the same flexibility in choosing what works best for their lifestyle.
Shelf life
The packaging standards and shelf life of Cialis, are better being a branded medicine. The expiry date is clearly mentioned, and storage instructions are simple.
With generic Tadalafil, shelf life can vary depending on the manufacturer. Make sure you always check the expiry date and buy from reliable pharmacies. Store both in a cool, dry place, away from moisture and sunlight.
Use for BPH (Benign Prostatic Hyperplasia)
Interestingly, both Cialis and Tadalafil are also approved for treating BPH along with Erectile Dysfunction. BPH is a problem in which the prostate gets enlarged and can lead to urinary problems.
This makes both options useful for men who are experiencing both ED and BPH. One pill, two benefits.
Side effects
Since both medicines are the same chemically, their side effects are also similar. Some common ones include:
- Headache
- Back pain
- Muscle aches
- Indigestion
- Flushing
- Nasal congestion
These effects are usually mild and go away on their own. But if you experience problems get medical help.
Conclusion
When it comes to Cialis vs Tadalafil, it really comes down to preference, budget, and trust in the manufacturer. Cialis has the brand reputation, while Tadalafil offers value for money without compromising on results. Both are safe, effective, and offer long-lasting results for men dealing with Erectile Dysfunction or an enlarged prostate.
The main difference is in the price and the brand name. If cost is not a concern and you prefer a product from a single trusted manufacturer, Cialis might be the right choice. But if you want a more affordable, equally effective option, then Tadalafil is a smart and safe alternative—as long as you get it from a good source.
Always consult your doctor before taking any medicine, and never buy from unverified online sellers.
Frequently Asked Questions
Does Tadalafil keep you hard after coming?
No, Tadalafil helps you get and maintain an erection, but it does not keep you hard after ejaculation. After climax, most men experience a refractory period during which another erection is not possible. Tadalafil can shorten this period in some cases, but it will not keep you hard immediately after coming.
Can Tadalafil cause dependency?
No, Tadalafil is not physically addictive. However, psychological dependence may develop if someone relies on it without addressing underlying health or emotional causes of ED. It’s best used as part of a comprehensive approach, including lifestyle changes and mental health support when needed.
Can I take 40 mg of Cialis daily?
No, taking 40 mg of Cialis daily is not recommended. The typical daily dose is 2.5 to 5 mg. Higher doses like 40 mg increase the risk of side effects such as Low Blood Pressure, headaches, and Priapism. Always follow your doctor’s guidance for safe and effective use.
Does Cialis help with performance anxiety?
Yes, Cialis may help men who experience ED due to performance anxiety by improving blood flow. However, it doesn’t directly treat anxiety. For long-term results, therapy or counseling may be helpful alongside medicine if psychological factors are involved.
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