How to Make Levitra More Effective: Know What Foods and Drugs to Avoid

Levitra is a prescription-only oral medicine to treat Erectile Dysfunction.

Its main ingredient is Vardenafil, which improves blood flow to the penile area.

Levitra allows the smooth muscles in your penis to relax so that the blood can easily flow into penis tissues and give you an erection.

However, there are certain things to remember when taking Levitra to increase its efficacy.

Things like when to take and how to take Levitra, along with what foods and drugs to avoid with this medicine, can help you get the best results.

Let’s dive deep into this article to answer your question: How to make Levitra more effective?

How to make Levitra more effective

To make Levitra more effective, knowing when and how to take it is essential.

Absorption of Vardenafil usually takes 30 minutes. However, this medicine can take 1 hour to show its peak effects.

When to take Levitra

It is recommended to consume Levitra an hour before sexual activity as it takes around an hour to reach its maximum concentration.

The maximum concentration of a drug allows it to work more effectively.

Therefore, Levitra might work better if you consume it 60 minutes before sexual intercourse.

How to take Levitra

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Taking pill

Levitra can be taken with or without food. It is advisable to consume it with light meals as high-fat meals might delay the onset of action.

Swallow the tablet whole with a glass of water.

Do not crush or chew the tablet.

Again, it is essential to consume Levitra about 60 minutes before sexual activity.

Levitra doesn’t work on its own. It is important to get sexually stimulated for this medicine to work.

Should I take Levitra on an empty or full stomach

Levitra can be taken on an empty or full stomach.

Like Viagra, Levitra is not preferred after a heavy or high-fat meal as doing so could cause the effect to delay.

Foods and drugs to avoid with Levitra

Like any other medicine, Levitra could react with different foods and drugs. It is advised to avoid some substances that can have adverse effects when taking Levitra. 

Let’s discuss the foods and medications to steer clear of when using Levitra:

Drugs to avoid

One should avoid taking certain medicines while taking Levitra as they may cause some side effects.

Here are some drugs which can interact when taken with Levitra.

  • Nitrates, like Nitroglycerin, Isosorbide
  • Alpha blocker medication, such as Doxazosin, Tamsulosin
  • Azole Antifungals, like Itraconazole, Ketoconazole
  • Macrolide Antibiotics, such as Clarithromycin and Erythromycin.
  • Other PDE5 inhibitors such as Tadalafil, Sildenafil

Foods to avoid

These are the food and beverages that you need to avoid when taking Levitra:

  • High-Fat meals: A heavy or high-fat meal should be avoided as the meal can reduce the absorption of the active ingredient in Levitra (Vardenafil) and make the drug less effective for you to have an erection.
  • Grapefruit Products: Grapefruit or grapefruit juice consumption can increase Viagra’s availability in the body, which can cause or worsen the side effects.
  • Alcohol: Taking Levitra with alcohol can lower blood pressure and worsen the side effect. It can result in dizziness, lightheadedness, fainting, headaches, and heart palpitations.


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Man taking pills

Levitra is a medicine that helps an individual to attain and hold an erection.

You can make it more effective if you take 30 minutes to 1 hour before engaging in sexual activity.

In addition, there are several things you can do to help make Levitra more effective, such as avoiding high-fat meals before taking the medication and reducing alcohol consumption.

Additionally, maintaining a healthy lifestyle, managing any underlying health conditions, and communicating openly with your doctor can all contribute to the effectiveness of Levitra in treating erectile dysfunction.

Frequently Asked Questions

How long does it take for Levitra to peak?

Levitra usually reaches peak concentration within 30-60 minutes after oral administration. However, it also depends on an individual’s health and the meal they consume before taking Levitra.

Does Levitra work on a full stomach?

Levitra works on an empty as well as a full stomach. However, consuming a light meal before taking this medicine is advisable, as a high-fat meal can reduce absorption.

Why would Levitra not work?

Many men make the error of taking Levitra just after eating. This may prevent the medications from being absorbed properly, reducing their effectiveness. Also, Levitra may not work if it is taken with certain medications or combined with alcohol or a high-fat meal.

Is Levitra good for the heart?

By influencing blood vessels throughout the body, Erectile Dysfunction drugs like Viagra, Cialis, and Levitra may enhance heart health. However, if you are a heart patient, please talk to your doctor before using any ED medication.

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Janet Fudge is a highly skilled and experienced pharmacologist who serves as a contributing writer for With a strong academic background from a premier US University and a passion for helping others, Janet has become a trusted voice in the pharmaceutical world. After completing her Doctor of Pharmacy degree, Janet embarked on a successful career in the pharmaceutical industry, working with various clients, including hospitals, retail pharmacies, and drug manufacturers. Her in-depth knowledge of pharmacology and dedication to patient-centered care has led her to excel in her field. As a writer for, Janet uses her wealth of expertise to provide readers with accurate, reliable, and up-to-date information on various topics related to medicine and healthcare. Her engaging writing style and ability to break down complex topics into easily digestible content make her a valuable resource for healthcare professionals and the general public.