Lisinopril and Cialis: About, Interaction, and More

All about Lisinopril and Cialis: Lisinopril is a prescription medication that helps treat heart failure and Hypertension.

It helps heart attack patients by increasing their chances of survival.

Cialis is an FDA-approved brand-name prescription medication.

It treats Erectile Dysfunction (ED) and Benign Prostatic Hyperplasia (BPH) symptoms.

Cialis increases the blood flow to the penis.

And it may improve your ability to achieve and maintain an erection.

Many factors can contribute to Erectile Dysfunction. One of the leading causes of ED is Hypertension.

Combining Lisinopril with Cialis may be beneficial.

But the two medicines may interact, so consult a doctor before taking them. 

The following article will help you learn more about taking Lisinopril and Cialis together.

If you are curious to know other ED medicines, read Know the Different Kinds of Erectile Dysfunction Pills

How does Lisinopril work

lisinopril and cialisSource: Getty_images_signature
lisinopril and cialis

Lisinopril is an Angiotensin-Converting Enzyme (ACE) inhibitor. 

Angiotensin is a chemical that narrows the blood vessels in the body. Thus, it increases blood pressure.

Angiotensin II raises blood pressure. 

ACE inhibitors block the activity of the enzyme ACE. 

ACE helps convert inactive Angiotensin I to active Angiotensin II.

ACE inhibitors prevent the conversion of Angiotensin I to Angiotensin II. This helps reduce blood pressure.

How does Cialis work

Cialis is a Phosphodiesterase type 5 (PDE5) inhibitor. It is the brand name of the prescription medicine Tadalafil.

PDE5 is an enzyme that decreases cyclic Guanosine Monophosphate (cGMP) levels.

It is responsible for blood flow regulation.

PDE5 medications function by inhibiting the activity of the enzyme PDE5 and increasing cGMP levels.

Hence, they aid in increasing penis blood flow. As a result, they assist in producing an erection.

Cialis remains in the body longer compared to other medicines used to treat ED.

And it would be best if you took the dose as prescribed by your doctor.

Consult a doctor about adjusting your dose if you experience any side effects.

Can you take Cialis and Lisinopril together

Lisinopril and Cialis belong to separate drug classes. 

Cialis is a PDE5 inhibitor, and Lisinopril is an ACE inhibitor. 

Although they have different purposes and working, both medicines affect blood pressure (BP). 

Both medicines may have blood pressure-lowering properties.

Combining Lisinopril with Cialis may not result in considerable side effects.

Yet, you should consult a doctor if you experience dizziness, lightheadedness, or fainting. 

Some side effects may occur at the beginning of treatment or after increasing dosage. They generally go away when you adjust to the medicine.

Erectile Dysfunction and Lisinopril

Erectile Dysfunction and LisinoprilSource: SHOTRPIME
Erectile Dysfunction and Lisinopril

According to research, Lisinopril is not likely to cause Erectile Dysfunction. 

It also states, Lisinopril does not influence orgasm, sexual desire, or erectile function.

For most men with high blood pressure, Lisinopril may help with ED.

The FDA has not cited ED as a side effect of Lisinopril.

Side effects of Lisinopril and Cialis

It may be safe to take Cialis and Lisinopril together if your doctor prescribes it.

But they might have some common side effects that include:

  • Headache
  • Dizziness
  • Diarrhea
  • Nausea
  • Cough and cold

Cialis also may have some severe side effects that include: 

  • Memory problems 
  • Blurred vision 
  • Prolonged erections (Priapism)

Although these side effects are rare, you should consult a doctor if you experience these.

Glossary
Angiotensin-converting enzymes (ACE) are proteins that convert Angiotensin I to Angiotensin II.
Priapism is a prolonged and painful erection of the penis, usually without sexual arousal.

Lisinopril and Cialis Drug Interactions

Taking Cialis with Nitrates may cause low blood pressure.

Some other medications that may interact with Cialis include:

  • Rifamycins 
  • Antibiotics 
  • Antifungals
  • Antidepressants 
  • Barbiturate

You should take Tadalafil only after seeing a doctor.

It’s best not to take Cialis with heart, blood pressure, and HIV drugs.

Lisinopril may interact with some of the following medications:

  • Diuretics: Taking it with Lisinopril may lead to lowering blood pressure
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): Lisinopril with NSAID may cause kidney damage
  • Lithium: Taking Lisinopril with Lithium may lead to a Lithium overdose
  • Sirolimus and Everolimus: Taking Lisinopril with them may raise the risk for Angioedema

Key Takeaways

Lisinopril is a Hypertension medicine. It has blood pressure-lowering properties.

Cialis helps treat Erectile Dysfunction and symptoms of BPH.

Both Cialis and Lisinopril aid in lowering blood pressure.

In rare cases, Lisinopril may cause long-term sexual performance issues.

But ED is not a common side effect of the medicine. 

You can take Lisinopril and Cialis together with your doctor’s approval. 

When starting treatment, you may have symptoms of low blood pressure.

Some side effects may go away after your body has had time to adjust to the medication.

If you’re interested in exploring natural remedies for ED, we recommend checking out our recommended reading. Remember that while some natural remedies may be effective, it’s essential to consult with your healthcare provider before trying new treatments or supplements.

Frequently Asked Questions

Is it safe to take Cialis?

Yes, it is safe to take Cialis when your doctor prescribes it. 
It is an FDA-approved prescription medication for Erectile Dysfunction.
But, for some people, Cialis may not be a safe option. 
It includes people with heart conditions and people who take medicines like nitrates.

How fast does Lisinopril work to decrease blood pressure?

After taking the first dose, Lisinopril starts acting immediately. 
But, you might not feel the effects of the medication immediately.
It is due to the infrequent symptoms caused by high blood pressure.

Does Cialis increase the size of the penis?

No, Cialis doesn’t make the penis bigger. The medicine causes a rise in blood flow. 
If the penis couldn’t be fully erect earlier, it may appear larger after taking Cialis.
Although Cialis doesn’t alter penis size, it may increase the ability to have an erection.

Can I drink alcohol while taking Lisinopril?

Lisinopril might make you lightheaded, and drinking alcohol may worsen this impact.
Avoid consuming alcohol with Lisinopril until you can estimate its effects.
The best course of action is not to consume alcohol while taking Lisinopril.

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Janet Fudge is a highly skilled and experienced pharmacologist who serves as a contributing writer for CheapMedicineShop.com. With a strong academic background from a premier US University and a passion for helping others, Janet has become a trusted voice in the pharmaceutical world. After completing her Doctor of Pharmacy degree, Janet embarked on a successful career in the pharmaceutical industry, working with various clients, including hospitals, retail pharmacies, and drug manufacturers. Her in-depth knowledge of pharmacology and dedication to patient-centered care has led her to excel in her field. As a writer for CheapMedicineShop.com, Janet uses her wealth of expertise to provide readers with accurate, reliable, and up-to-date information on various topics related to medicine and healthcare. Her engaging writing style and ability to break down complex topics into easily digestible content make her a valuable resource for healthcare professionals and the general public.