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How Long Does Cialis Stay in Your System? Facts You Might Have Missed

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Cialis is used to treat Erectile Dysfunction in men or Assigned Males at Birth (AMAB).

Erectile Dysfunction (ED) is the inability of men or AMAB to get and maintain an erection.

Cialis, which contains the active ingredient Tadalafil, is a highly effective medication for treating ED.

However, you might be wondering, “How long does Cialis stay in your system after taking it?”

This article will provide information about the duration of Cialis in your body and address related questions.

How long does Cialis stay in your system

How long does Cialis Stay in your systemSource: freepik
Cialis intake

Cialis is a common Erectile Dysfunction medicine known for its effective use in treating ED.

Besides helping achieve firm erections, Cialis also helps maintain an erection.

According to the US Food and Drug Administration (FDA), Cialis stays for 36 hours in the body.

The half-life of Cialis is approximately 17.5 hours.

This means that it takes around 17.5 hours for the concentration of Tadalafil (the active ingredient in Cialis) in your body to decrease by half.

But the effects of Cialis last for up to 36 hours, earning it the nickname “the Weekend Pill.”

So, if you take Cialis on a Friday evening, its effects could last until Sunday.

This provides a spontaneity to engage in sexual activities compared to some other ED pills like Viagra, which lasts for about 4-5 hours.

Although Cialis can stay active in your body for 36 hours, it doesn’t mean you’ll have a continuous erection.

Cialis can only help you get an erection when you are sexually aroused.

An erection will naturally go away after sexual activity.

However, it might help you achieve another erection soon after ejaculation, potentially reducing your refractory period.

Although Cialis can help maintain an erection for a longer duration, that does not mean it helps you last longer.

To clear all your doubts related to the usage of Cialis, read Does Cialis Make You Last Longer? Know the Truth.

Note
Refractory period is the recovery time when your body takes a break before it can be ready for another round of sexual activity.

Factors that affect how long Cialis will last

Various factors may affect the working of Cialis, including the time it lasts. 

These factors include the individual’s age, medical history, and current medicines.

Let’s discuss in detail how these factors affect the working of Cialis.

Overall health

Physical and mental well-being plays a vital role in the medicine’s effectiveness. 

If you have any underlying medical conditions, it will have adverse effects on your body. 

This action may not allow Cialis to work to its full ability. Thus, potentially reducing its duration of action.

The medications used to treat particular medical conditions can also have an impact on how long Cialis (Tadalafil) lasts.

The interaction between Cialis and these medications can slow down the duration of Cialis.

If you want to gain deep insights regarding the interaction of Cialis (Tadalafil), read Understanding Tadalafil Interactions.

Age

As you age, your metabolism gets slow and weak.

A weak metabolic system is more sensitive to the effects of medicines.

People with slower metabolisms may require more time to process medicines. Thus causing them to stay in the body longer than usual.

This extended presence increases the likelihood of drug interactions and side effects.

Eating habits

Taking grapefruit or its beverages increases the amount of Tadalafil in your blood levels.

Grapefruit contains compounds that can inhibit the activity of CYP3A4 enzymes, which are responsible for metabolizing various medications, including Cialis.

When these enzymes are inhibited, they cannot break down the medication effectively.

Thus, leading to higher levels of Tadalafil in the bloodstream.

This can extend the duration of action of Cialis and potentially intensify the side effects of the medication.

Therefore, it is essential to avoid these foods to maximize the effects of Cialis.

Apart from grapefruit, alcohol can also affect the working of Cialis. To explore information on alcohol and Cialis, read Is it Safe to Take Cialis and Alcohol Together.

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  • Pros and cons of Cialis long-lasting effects

    How does Cialis workSource: syda_production
    Pros and Cons of Cialis long-lasting effects

    The long duration of action of Cialis (Tadalafil), can have both advantages and disadvantages.

    Here we have explained both pros and cons in detail.

    Advantages

    1. Extended flexibility:

    The primary advantage of a long duration of action is the increased flexibility it provides.

    With Cialis, you can enjoy a “spontaneous” sex.

    You don’t need to plan the Cialis dosages in advance of intimate moments as rigorously because the medication remains effective for up to 36 hours.

    This flexibility can be a significant benefit for couples who prefer more spontaneous encounters.

    2. Increased sexual confidence:

    Knowing that the medication remains active for an extended period can help reduce sexual performance anxiety.

    This can boost sexual confidence and overall sexual experience.

    Disadvantages

    1. Increased chances of side effects:

    The long duration of action can lead to an increased risk of experiencing side effects.

    These side effects, such as headaches, back pain, or nasal congestion, may persist over an extended period.

    This can be bothersome for some users.

    2. Potential for Interactions:

    The extended presence of the medication in the body may increase the likelihood of interactions with other medications, medical conditions, and food.

    It is crucial for users to be cautious and consult with a doctor to avoid harmful drug interactions.

    Caution:
    Do not take Cialis with Nitrates as this combination can lower blood pressure to dangerous levels.

    Conclusion

    Cialis is the longest-lasting ED pill, which may last up to 36 hours. 

    This duration of action may vary from person to person due to factors like age, dietary choices, and overall health.

    Long-lasting pills like Cialis allows for greater spontaneity to engage into sexual activities.

    However, it may also increase the risk of interactions and side effects.

    Cialis is a prescription-based medicine; thus, consulting a doctor is necessary.

    Frequently Asked Questions

    Is Cialis available without a prescription?

    No, Cialis is a prescription medicine which is not available over the counter. 
    You require a valid prescription from a doctor to buy Cialis (Tadalafil).

    How long does Cialis take to eliminate from your body?

    According to the FDA, Cialis lasts up to 36 hours in your body. 
    However, it may take 5 days for it to totally leave your system.
    It is advisable to consult a doctor before starting this medicine as its long stay in your body could impact how other medicines work for you.

    How long does Cialis take to make you hard?

    Cialis begins to work within 30 minutes of taking it. 
    However, it may take about one to two hours to get the full effects of the medicine.

    What is the best time to take Cialis?

    You should take Cialis at least 30 minutes to an hour before sexual intercourse. 
    After taking it, the medicine may last up to 36 hours in your body.

    What is the half-life of Cialis?

    The half life of Cialis is 17.5 hours.
    This means it takes 17.5 hours to decrease the concentration of Tadalafil (the active ingredient in Cialis) in the body to half.

    Citations: Cheap Medicine Shop only refers to credible, authoritative sources for our content. If you’re curious about how we ensure the integrity of our content, we encourage you to read our Content Information Policy.

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    Photo of author Janet Fudge
    Janet Fudge is a highly skilled and experienced pharmacologist who serves as a contributing writer for CheapMedicineShop.com. With a strong academic background from a premier US University and a passion for helping others, Janet has become a trusted voice in the pharmaceutical world. After completing her Doctor of Pharmacy degree, Janet embarked on a successful career in the pharmaceutical industry, working with various clients, including hospitals, retail pharmacies, and drug manufacturers. Her in-depth knowledge of pharmacology and dedication to patient-centered care has led her to excel in her field. As a writer for CheapMedicineShop.com, Janet uses her wealth of expertise to provide readers with accurate, reliable, and up-to-date information on various topics related to medicine and healthcare. Her engaging writing style and ability to break down complex topics into easily digestible content make her a valuable resource for healthcare professionals and the general public.
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