Find Out What are the Best Nitric Oxide Supplements for ED

Impotence or Erectile Dysfunction is the inability to get erect enough during sex.

Several conditions, such as Anxiety, Depression, and hormonal imbalance, can lead to ED.

According to Translational Andrology and Urology, maintaining a healthy lifestyle may help in lowering the risk of ED.

Several medicines like Viagra can treat Erectile Dysfunction. 

Apart from the medications, Nitric Oxide supplements may also help treat ED.

This article will help you answer the question, what are the best Nitric Oxide supplements for ED?

Nitric Oxide and its relation with Erectile Dysfunction

Nitric Oxide and its relation with Erectile DysfunctionSource: Getty_images_signature
nitric oxide relation

Nitric Oxide, or NO, is a free radical molecule that is produced by our body naturally.

It is essential in neurotransmission, regulating blood flow, immune response, and psychological processes.

It helps in muscle recovery and improves our stamina and performance. 

There is also an effect of Nitric Oxide on the penis. According to research, Nitric Oxide has an essential role in the erection of the penis. 

When a person gets sexually aroused, the nerve ending in the penile region releases NO.

The release of NO relaxes the smooth muscle cells in the penile arteries. 

The relaxation allows the flood of blood to the penis, which results in an erection.

Due to ED, the production of Nitric Oxide may get impaired, which results in difficulty in achieving and maintaining an erection. 

ED medicine and some NO supplements can help increase the production of Nitric Oxide, which can help manage impotence.

Best Nitric Oxide supplements for ED

The market is flooded with Nitric Oxide supplements claiming to treat Erectile Dysfunction.

You need to know which supplement is safe and which may help in impotence.

According to Mayo Clinic, L-arginine, DHEA, and Ginseng are some of the best Nitric Oxide supplements for ED. 

Let us take a look at all effectiveness and side effects of the NO supplements in the table below.

SupplementEffectivenessSide Effects
L-arginineIt may help with ED by stimulating blood flow. It should be taken in high doses for the treatment.It is generally safe but may have side effects such as nausea and cramps. It is not recommended to take it with Viagra.
Propionyl-L-carnitineWhen taken with Sildenafil, L-arginine may help treat ED by increasing blood flow to the penis.It is generally safe to consume.
DHEADHEA supplements may potentially improve erectile function in men with ED.Consuming DHEA is safe, but it may cause acne.
GinsengPanax Ginseng may enhance sexual function in men experiencing ED. Premature ejaculation is treated.Consumption of Ginseng is usually considered safe if taken for the short term. But you may experience some side effects such as insomnia and headaches.
L-citrullineL-citrulline is an amino acid that gets converted to L-arginine, which is converted to NO. It can help in treating mild to moderate cases of ED.Some people may experience Diarrhea and gastrointestinal discomfort.

Benefits of Nitric Oxide supplement

Benefits of Nitric Oxide supplementSource: Getty_images_signature
know the benefits

Nitric Oxide plays a vital role in our body.

Maintaining the levels of Nitric Oxide is vital for a healthy body.

Nitric Oxide supplements have a variety of benefits. 

These are some of the benefits of taking Nitric Oxide supplements.

Improves heart health

Nitric Oxide makes blood vessels wider and helps to improve blood flow. It keeps the blood pressure low, which keeps the heart healthy.

Treat Erectile Dysfunction

Nitric Oxide supplements help with increasing the flow of blood to the penis. 

This blood flow helps to get an erection. 

It’s also very important to know that NO supplements may or may not work in treating Erectile Dysfunction.

Help with muscle soreness

Nitric Oxide supplements enhance the flow of oxygen to the muscles and reduce fatigue. 

It helps in improving performance and relaxation from muscle soreness after exercising.

Nitric Oxide supplements should not be consumed without a doctor’s consultation.

Does Nitric Oxide supplement works for ED

Many Nitric Oxide supplements are marketed as a treatment for ED. 

Some Nitric Oxide supplements may help in treating mild and moderate ED. 

According to a study by Future Science OA, Nitric Oxide supplements may help manage impotence.  

But, there is not enough research that can prove that NO supplements can help with ED. 

The NO supplements may or may not work in treating impotence.

You should take medicines containing Sildenafil and Tadalafil to treat Erectile Dysfunction effectively.   

Consult a doctor before taking any medicine or Nitric Oxide supplement.

Is there any risk involved in taking Nitric Oxide supplements

Nitric Oxide supplements can also have risks and side effects like other supplements or medications.

Most people do not experience any side effects after consuming the supplement.

But, the side effects may vary in individuals.

Taking Nitric Oxide supplements can cause a drop in blood pressure.

The supplement should not be mixed with medicines of impotence. According to FDA, you should not incorporate any supplement with medications. 

Some people may experience digestive issues such as Diarrhea or stomach cramps. 

You may also experience allergic reactions after taking Nitric Oxide supplements.

Consulting a healthcare professional before taking supplements is always a good idea.


Supplements can help in dealing with deficiencies. 

Nitric Oxide has an important role in our body.

Nitric Oxide supplements can help in managing impotence.

L-arginine and L-citrulline are the best Nitric Oxide supplements for ED. 

Consuming supplements have some benefits, such as increasing our performance, the health of the heart, and treating ED.

You may experience some side effects, such as digestive issues and headaches. 

Although Nitric Oxide supplements have health benefits, there is not enough research on their role in treating ED.

Visiting a doctor before taking any supplement for treating ED is necessary.

Frequently Asked Questions

Can Erectile Dysfunction be treated with supplements?

Yes, Nitric Oxide supplements such as L-arginine may help in managing Erectile Dysfunction. However, more research is needed on using Nitric Oxide supplements to treat ED.

Does Nitric Oxide help with stamina?

Yes, Nitric Oxide can help increase our stamina and aid muscle soreness.

Can I take Nitric Oxide with Viagra?

It would be best not to take Viagra and Nitric Oxide supplements together. FDA does not recommend taking medicine and supplements together.

Can you take Nitric Oxide supplements daily?

Yes, you may take the Nitric Oxide supplements daily. However, the dosage of Nitric Oxide supplements varies in individuals. You should consult a healthcare provider for the correct dosage idea.

What are the top Nitric Oxide supplements for ED?

The supplements such as L-arginine and L-citrulline are the top NO supplements that might help you in treating ED.

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Jim Carson is a highly skilled and dedicated medical writer passionate about advancing medical practice. With years of experience in the field of medical sciences, Jim has made significant contributions to various studies aimed at improving healthcare outcomes. He currently writes for, providing expert insights and knowledge on various topics. Jim's expertise extends to various areas, including drug interactions, dosages, side effects, and best practices for medication use. In Los Angeles, Jim lives with his loving wife, children, and beloved pets. He deeply values spending time with his family and cherishes their presence. When he's not writing, Jim enjoys watching football games and staying updated with the latest sports news. Jim's writing shines through his commitment to advancing medical practice and improving healthcare outcomes. Readers can trust Jim's articles to be informative, accurate, and reliable, making him a trusted pharmaceutical information source for the website's audience.