Polycystic Ovary Syndrome (PCOS) is a hormonal disorder that affects millions of women of reproductive age.
It can cause several issues, like irregular periods, high blood pressure, and acne. Along with these, it can also take a toll on your mental health by causing Anxiety.
If left untreated, it can also lead to serious complications like infertility. Effective treatment with the help of medications and lifestyle changes can help manage PCOS and avoid complications.
Spironolactone is one of the most widely used medications for PCOS.
This article will discuss all about Spironolactone for PCOS, including its working and dosage. We will also explore the potential side effects of Spironolactone.
What is Spironolactone
Spironolactone is usually sold under the brand name Aldactone as a prescription medicine. It is a Diuretic that can help remove excess fluid from the body.
Medical practitioners prescribe Spironolactone to treat several conditions, including heart failure, high blood pressure, and fluid-up from liver disease.
Spironolactone is also classified as an anti-Androgen. This means that it can inhibit Androgen effects in the body, making it beneficial for people with PCOS.
The next section will explore if and how Spironolactone for PCOS works.
Spironolactone for PCOS: How Does it Work?

Polycystic Ovary Syndrome is one of the most common hormonal conditions affecting people with ovaries. It affects about 8 to 13% of women of reproductive age globally.
An imbalance in hormones, i.e., abnormally high androgen levels, can trigger these PCOS symptoms.
High Androgen levels can also contribute to Hirsutism (excess hair growth on the face, chest, and back) and hair loss from the scalp.
Spironolactone acts as an anti-androgen by blocking androgen receptors, including the receptors on hair follicles.
This prevents Testosterone from binding and causing symptoms like Hirsutism. Spironolactone also reduces the production of Androgens in the ovaries and adrenal glands, thereby treating PCOS.
To better understand how to lower Testosterone to treat PCOS, read How to Lower Testosterone PCOS?
Spironolactone for PCOS: Dosage
Spironolactone is generally available in 25 mg, 50 mg, and 100 mg tablets. For those who have trouble swallowing pills, Spironolactone is also available in the form of oral liquid.
For Hirsutism, doctors usually prescribe 50 mg doses twice a day. They may increase the dose to 100 mg if the current dose is insufficient.
It is essential to seek medical advice before taking Spironolactone to treat PCOS and avoid potential side effects effectively.
Spironolactone for PCOS: Side Effects

Like any other medicine, Spironolactone can also cause side effects in some cases. The potential side effects of Spironolactone may include
- Hyperkalemia (especially in women aged 45 years or more)
- Dizziness
- Breast tenderness
- Vomiting
- Headaches
- Nausea
- Dehydration
- Irregular periods (highly unlikely if you’re also on birth control)
- Diarrhea
Spironolactone can also affect electrolyte levels like potassium in the body. Excess potassium can cause heart rhythm issues.
Additionally, Spironolactone can also cause birth defects, especially in male fetuses. This medication can affect the development of sex organs.
Do not take Spironolactone if you are pregnant or planning to get pregnant. Consult your healthcare provider for a more suitable medication for PCOS in such cases.
Do you want to know more about other ways to treat PCOS? Read Balancing Hormones: A Comprehensive Guide to Effective PCOS Treatment.
Final Outlook
Polycystic Ovary Syndrome is a common hormonal condition affecting millions of women globally.
It can cause menstrual cycle dysfunction, acne, excess hair growth on the face, chest, and back, and hair loss on the scalp.
If left untreated, PCOS can also cause complications like infertility and Type-2 Diabetes. This makes it extremely important to receive suitable PCOS treatment.
The treatment usually involves lifestyle changes and medications. One commonly used PCOS medication is Spironolactone.
Spironolactone for PCOS works as an anti-Androgen to treat symptoms like Hirsutism.
Doctors generally prescribe 50 mg doses twice a day for treating PCOS symptoms, which may be altered as per the severity of symptoms.
It is essential to consult a medical professional before taking Spironolactone to avoid potential side effects like dehydration, irregular periods, and pregnancy complications.
Frequently Asked Questions
Are there any interactions between Spironolactone and oral contraceptives?
No, combining Spironolactone with oral contraceptives can enhance its effectiveness in managing PCOS symptoms.
However, the specific regimen should be discussed with your healthcare provider. Buy Now
Can Spironolactone cure PCOS?
No, Spironolactone does not cure PCOS but can help manage its symptoms, such as acne, irregular periods, and Hirsutism, by regulating androgen levels. Buy Now
How long does it take for Spironolactone to show results in PCOS?
Results from Spironolactone for PCOS may vary for each person, but improvements may be noticed within a few months.
Patience and consistent medication use are essential. Buy Now
Are there any dietary restrictions while taking Spironolactone for PCOS?
No, there are no specific dietary restrictions, but maintaining a healthy lifestyle can complement the effectiveness of the medication. Buy Now
What should I do if I miss a dose of Spironolactone?
If you miss a dose of Spironolactone, take it as soon as you remember. However, if it’s close to the next scheduled dose, skip the missed one.
Do not double the dose to catch up. Consistent adherence to the prescribed schedule is important. Buy Now
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