What is Actorise 100 Injection

Actorise 100 Injection, manufactured by Cipla Ltd, contains Darbepoetin alfa (100mcg), an Erythropoiesis-stimulating agent (ESA). It primarily treats Anemia caused by Chronic Kidney Disease (CKD) or chemotherapy. Stimulating the bone marrow to produce more red blood cells helps reduce the need for blood transfusions. It improves oxygen delivery to tissues, alleviating fatigue and weakness associated with anemia.

This injection is administered under medical supervision to ensure accurate dosing and minimize risks. It is a prescription-only medication given subcutaneously (under the skin) or intravenously (into a vein), depending on the patient's condition and doctor's recommendation.

Regular monitoring is essential while using this medication. Patients should undergo frequent blood tests to track hemoglobin and iron levels and overall blood health. If side effects such as severe headache, dizziness, shortness of breath, or high blood pressure occur, medical attention should be sought immediately.

Store Actorise 100 in a refrigerator (2 - 8°C), ensuring it does not freeze. Do not shake the vial. Keep it away from direct sunlight and out of children's reach. Proper storage helps maintain its effectiveness and prevents degradation.

What are the benefits of Actorise 100 Injection

Actorise 100 works by stimulating the bone marrow to produce more red blood cells, helping to manage anemia effectively. It contains Darbepoetin alfa, an erythropoiesis-stimulating agent that boosts hemoglobin levels and improves oxygen transport in the body.

Key benefits include:

• Stimulates red blood cell production in Anemia caused by Chronic Kidney Disease or chemotherapy.
• Reduces the need for blood transfusions, lowering associated risks.
• It helps improve energy levels and reduces fatigue, enhancing daily activities.
• Supports better oxygen transport, promoting overall well-being.
• It can be administered subcutaneously or intravenously, offering flexible treatment options.

How to use Actorise 100 Injection

Actorise 100 is a prescription-only medication and should be administered under a healthcare professional's supervision. It is given as an injection either subcutaneously (under the skin) or intravenously (into a vein) based on medical advice. General guidelines include:

• Hemoglobin levels and individual response determine dosage and frequency.
• Strictly follow your doctor's instructions to avoid complications.
• Regular blood tests are necessary to monitor treatment progress and adjust dosage.
• Do not self-administer unless adequately trained by a healthcare provider.

Strengths and substitutes

Actorise has various strengths and substitutes. Your doctor may adjust your dosage based on your specific condition and response to treatment. 

Available strengths include:

View all substitutes

What are the side effects of Actorise 100 Injection

Generally safe when taken as prescribed, Actorise 100 may cause mild to moderate side effects, including:

• High blood pressure (hypertension)
• Headache or dizziness
• Nausea and vomiting
• Injection site reactions (pain, swelling, redness)
• Skin rash or itching
• Shortness of breath
• Flu-like symptoms (fever, chills, muscle aches)

Seek immediate medical attention if severe allergic reactions or sudden shortness of breath occur.

Safety Advice

Liver disease

Patients with liver disease should consult their doctor before using Actorise 100, as dosage adjustments may be needed.

Kidney impairment

This medication is commonly used for kidney-related anemia; however, dosage should be carefully monitored to avoid complications.

Pregnant and breastfeeding women

Limited data exist on its safety during pregnancy or breastfeeding. Consult a doctor before use to assess risks and benefits.

Avoid

Do not use Actorise 100 if you are allergic to Darbepoetin alfa or its ingredients. Avoid self-administration unless trained; do not mix it with other injections in the same syringe.