What is Actorise 25 Injection

Actorise 25 Injection is a prescribed Erythropoiesis-Stimulating Agent (ESA) for managing Anemia in patients undergoing chemotherapy or diagnosed with Chronic Kidney Disease (CKD). It contains Darbepoetin alfa, an ESA that encourages the bone marrow to produce more red blood cells, thereby reducing the need for blood transfusions and improving oxygen transport.

This injectable medication is strictly administered under medical supervision and is primarily prescribed for patients undergoing dialysis or chemotherapy. It helps manage Anemia-related fatigue and weakness, improving overall well-being. The dosage varies based on individual hemoglobin levels, and proper adjustments are necessary to prevent complications like hypertension or cardiovascular risks. Regular blood tests are crucial to monitor progress and effectiveness.

Cipla Ltd manufactures Actorise 25, which must be stored in a refrigerator to maintain potency. Freezing or shaking the injection may affect its stability, so it should be handled carefully. Always check the expiration date before use and strictly follow the prescribed storage guidelines to ensure its effectiveness.

What are the benefits of Actorise 25 Injection

Actorise 25 provides essential benefits for managing Anemia. Key benefits include:

• Boosts red blood cell production: Stimulates the bone marrow to produce more RBCs.
• Reduces fatigue and weakness: Improves oxygen supply in the body, reducing symptoms of Anemia.
• Decreases the need for blood transfusions: Helps maintain hemoglobin levels naturally.
• Effective for CKD and chemotherapy-induced Anemia: Approved for use in kidney disease and cancer patients.
• Longer half-life than Erythropoietin: Requires less frequent dosing.

How to use Actorise 25 Injection

Actorise 25 is a prescription-only medication and should be administered under a healthcare professional's supervision. It is given as an injection either intravenously (into a vein) or subcutaneously (under the skin) based on medical advice. 

General guidelines include:

• Hemoglobin levels and individual response determine dosage and frequency.
• Strictly follow your doctor's instructions to avoid complications.
• Regular blood tests are necessary to monitor treatment progress and adjust dosage.
• Do not self-administer unless adequately trained by a healthcare provider.

Strengths and substitutes

Actorise has various strengths and substitutes. Your doctor may adjust your dosage based on your specific condition and response to treatment. 

Available strengths include:

View all substitutes

What are the side effects of Actorise 25 Injection

Generally safe when taken as prescribed, but some may experience mild to moderate side effects:

• High blood pressure
• Injection site pain or redness
• Swelling in the limbs
• Shortness of breath
• Dizziness or headache
• Increased risk of blood clots
• Nausea or vomiting

Seek medical help if any side effects persist or worsen.

Safety Advice

Liver disease

Patients with liver problems should use Actorise 25 cautiously as the liver metabolizes medications. Regular monitoring and dose adjustments may be required under medical supervision.

Kidney impairment

Actorise 25 is mainly for chronic kidney disease patients but requires regular hemoglobin level monitoring. Patients with advanced kidney disease should use this medication strictly under nephrologist guidance.

Pregnant and breastfeeding women

Actorise 25 should only be used during pregnancy or breastfeeding if prescribed by a doctor. The medication can cross the placenta or enter breast milk, so careful medical supervision is essential.

Avoid

Avoid driving or operating machinery if you experience dizziness or headaches while using this medication. Do not consume alcohol, as it can increase side effects and interfere with the treatment's effectiveness.