Alphalan 5 Mg Tablets
| Pack Size | Price | Qty | Unit Price |
|---|---|---|---|
| 25 Tablet/s | $41.93 | $1.68 | |
| 50 Tablet/s | $81.76 | $1.64 | |
| 75 Tablet/s | $120.45 | $1.61 |
What is Alphalan 5 mg
Alphalan 5 mg is an oral antineoplastic medication primarily prescribed to treat Multiple Myeloma and certain other types of Cancer, including Ovarian Cancer, Breast Cancer, and certain Lymphomas in adult patients. Its active ingredient is Melphalan, which belongs to the class of nitrogen mustard alkylating agents.
This medicine works by interfering with the DNA replication process in rapidly dividing cells, particularly targeting cancer cells. Alphalan tablets can be used as part of combination chemotherapy regimens or as a single agent, depending on the specific cancer being treated. In addition to its use in active cancer treatment, it may also be prescribed as maintenance therapy in certain cases.
Alphalan 5 mg is manufactured by Natco Pharma Ltd, a leading pharmaceutical company specializing in oncology medications. Side effects of Melphalan can range from mild to severe and may include bone marrow suppression (leading to decreased blood cell counts), nausea, vomiting, mouth sores, and hair loss.
Regular blood tests are essential during treatment to monitor for potential complications, particularly those affecting the blood-forming cells in the bone marrow.
What are the benefits of Alphalan 5 mg
Alphalan 5 mg works through its active ingredient, Melphalan, which is a bifunctional alkylating agent that forms cross-links with DNA. This cross-linking prevents DNA replication and RNA synthesis, ultimately leading to cell death. The medication specifically targets rapidly dividing cells, which makes it particularly effective against cancer cells that typically divide more rapidly than normal cells.
Alphalan tablets offers multiple therapeutic benefits:
- Effectively destroys cancer cells in multiple myeloma, providing disease control.
- Helps reduce tumor burden in patients with advanced Ovarian Cancer.
- It can be used in the palliative treatment of certain Breast Cancers and Lymphomas.
- Available in oral form, allowing for convenient home administration.
- It can be part of high-dose therapy regimens before stem cell transplantation.
How to take Alphalan 5 mg
Alphalan is a prescription-only medication that should be taken precisely as directed by your oncologist. Here are the general guidelines:
- Take the Alphalan tablet on an empty stomach at least 30 minutes before meals.
- Swallow the tablet whole with a full glass of water.
- Do not crush, chew, or break the Alphalan tablets.
- It is not recommended to exceed the prescribed dose under any circumstances.
Consult a practicing healthcare professional for personalized dosage and duration instructions. They will determine the best regimen based on your health condition.
Strength and substitutes
The strength and substitutes available for Alphalan are:
| $22.8/10 Tablets |
What are the side effects of Alphalan 5 mg
Alphalan is a potent medication that may cause significant side effects. These include:
- Nausea and vomiting
- Mouth sores and oral ulcers
- Hair loss or thinning
- Increased risk of infection
These adverse effects may resolve on their own when the body adjusts. However, immediate medical attention is required for fever, unusual bleeding, or severe weakness.
Safety Advice
People with liver impairment may experience increased drug exposure and toxicity with Alphalan 5. In severe liver disease, alternative therapies should be considered. Regular liver function tests should be performed before and during treatment to monitor hepatic function.
Alphalan, used in Cancer treatment, requires caution in kidney impairment as it is excreted through the kidneys. In severe renal failure, lower doses and close blood count monitoring are essential to prevent complications.
Alphalan (Pregnancy Category D) is contraindicated in pregnancy due to fetal risk. Women should use contraception during and for 6 months after treatment. Breastfeeding must be stopped, as the drug may pass into breast milk and harm the infant.
Avoid live vaccines during and for several months after treatment with Alphalan due to the potential for serious vaccine-related infections. Grapefruit and its juice should also be avoided, as they may increase drug concentration.
FAQs
What is the purpose of Alphalan 5 mg Tablets?
Alphalan is primarily used to treat Multiple Myeloma. It's also prescribed for certain types of Ovarian Cancer, advanced Breast Cancer, and some non-Hodgkin's Lymphomas. The medication works by damaging cancer cell DNA, preventing their replication and growth.
How should I take Alphalan 5 mg Tablets for best results?
Take Alphalan on an empty stomach at least 30 minutes before food. Swallow the tablet whole with water without breaking or crushing it. Follow your oncologist's precise dosing schedule, which may involve cycles of treatment rather than continuous daily use.
Can Alphalan 5 mg Tablets interact with other medications I am taking?
Yes, Alphalan may interact with numerous medications, including other chemotherapy drugs, immunosuppressants, live vaccines, and some antibiotics. Always provide your oncologist with a complete list of all medications you're taking, including supplements and over-the-counter drugs, to prevent potentially dangerous interactions.
How does Alphalan 5 mg Tablets work in the body?
Alphalan works as an alkylating agent that creates cross-links in DNA strands of rapidly dividing cells. This prevents DNA replication and RNA synthesis, ultimately leading to cell death. While it targets all rapidly dividing cells, cancer cells are particularly vulnerable due to their accelerated division rates.
What precautions should I take while on Alphalan treatment?
Practice strict infection prevention measures as Alphalan suppresses your immune system. Monitor for signs of infection, unusual bleeding, or bruising. Avoid crowds and people with contagious illnesses. Stay well-hydrated and maintain good oral hygiene to reduce mouth-sore complications. Attend all scheduled blood tests to monitor for side effects.
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