Polycystic Ovary Syndrome (PCOS) and Cushing’s Syndrome are two endocrine disorders that can raise the risk for Diabetes.
They are both a result of hormonal imbalances in the body, caused by different hormones.
Since they both result from the improper functioning of the endocrine system, many people can often get confused between the two.
This article is a comprehensive guide about Cushing Vs PCOS. We will differentiate them on the basis of symptoms, causes, complications, and treatments.
Cushing Syndrome Vs PCOS: The Basics
Polycystic Ovary Syndrome is an endocrine disorder commonly affecting women. About 8 to 13% of women of reproductive age have PCOS globally.
PCOS is primarily characterized by the excess production of Androgens in the body that leads to a hormonal imbalance. Polycystic ovaries and irregular periods can also characterize PCOS.
On the other hand, Cushing’s disease (CD) is a rare endocrine disorder that occurs when the body overproduces Cortisol, a hormone related to the body’s stress response.
Both PCOS and Cushing’s disease are progressive, i.e., they can worsen over time if left untreated.
To learn more about how PCOS affects your endocrine system, read Is PCOS an Endocrine Disorder?
Cushing Vs PCOS: What’s the Difference
Source: Signature-imageWe know that both Cushing’s Syndrome and PCOS are endocrine disorders and progressive.
Both these conditions are triggered by the overproduction of certain hormones.
However, these conditions differ, particularly in their symptoms, causes, and treatment.
This section will elaborate on Cushing vs PCOS in detail.
Symptoms
The symptoms of PCOS may include excess hair growth, irregular periods, acne, and weight gain.
Symptoms of Cushing’s disease may include blurry vision, muscle weakness, rounded face, and weight gain.
Weight gain is a common symptom of both conditions. However, PCOS typically causes weight gain in the abdominal area, also sometimes referred to as PCOS belly.
In contrast, people with CD may gain weight above the collar bone, back of the neck, and face.
Causes
High levels of male sex hormones like Testosterone are known to cause PCOS symptoms. At the same time, overproduction of the stress hormone Cortisol can cause Cushing’s disease.
Factors like inflammation, genetics, and insulin resistance can cause a hormonal imbalance that may lead to PCOS.
While several types of tumors, like Adrenal tumors, Ectopic ACTH-producing tumors, and Pituitary tumors, can cause Cushing’s Disease.
Complications
Neglecting the symptoms of either PCOS or Cushing can be dangerous.
While PCOS can cause serious complications like infertility, Cushing’s disease can lead to a heart attack or stroke in some cases.
Both these conditions can be a risk factor for Depression also. It is necessary to seek treatment to avoid such complications.
PCOS can take a toll on your mental health and cause Depression in some cases. To learn more, read Examining the Association Between PCOS and Depression.
Treatment
Source: Signature_imageTreating Cushing’s disease often involves surgery, medication, or radiation therapy to address the overactive pituitary gland.
Whereas PCOS treatment involves lifestyle changes like workouts and diet along with medications. Some first-choice medications for PCOS include Metformin and Spironolactone.
Summing Up
PCOS and Cushing’s disease are endocrine disorders that can worsen over time if left untreated.
While the overproduction of Androgens triggers PCOS, excess cortisol levels may trigger Cushing’s disease.
Irregular periods, acne, and weight gain (abdominal) may help identify PCOS. On the other hand, muscle weakness, blurry vision, and a rounded face are common symptoms of Cushing’s disease.
Several types of tumors can cause Cushing, whereas genetics and other lifestyle factors can result in PCOS.
When we come to the treatment of Cushing Vs PCOS, Cushing’s Disease can involve surgery and medications. In comparison, PCOS may be treated with medications and lifestyle changes.
It is essential to seek treatment for either of the conditions to avoid complications like infertility or stroke.
Frequently Asked Questions
Can Cushing’s disease and PCOS coexist in the same person?
While it’s rare, a person can have both Cushing’s disease and PCOS. Consult with a healthcare professional for accurate diagnosis and tailored treatment.
Can stress worsen symptoms of Cushing’s disease or PCOS?
While stress doesn’t directly cause these conditions, it can exacerbate symptoms. Stress management techniques may be beneficial in overall health and symptom control.
Can Cushing’s disease and PCOS be prevented?
While there’s no guaranteed prevention for either condition, maintaining a healthy lifestyle, managing stress, and seeking prompt medical attention for symptoms may reduce the risk or severity.
Can weight loss improve symptoms of PCOS?
Yes, weight loss can positively impact PCOS symptoms, particularly in cases where Obesity is a contributing factor. Combining a healthy diet and regular exercise may help regulate hormones and improve overall well-being.
Is there a cure for Cushing’s disease or PCOS?
Cushing’s disease may be cured through surgery to remove the tumor, causing excess cortisol production. PCOS, however, doesn’t have a cure, but symptoms can be effectively managed through lifestyle changes and medications.
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