What is Campto 40 mg/2 ml injection

Campto 40 mg/2 ml is a chemotherapy medication used to treat metastatic colon and rectal Cancer. It contains Irinotecan Hydrochloride, which is in a class of antineoplastic medications called Topoisomerase I inhibitors.

Irinotecan interferes with the development of Cancer cells and kills them. It converts the body into its active form, SN-38, which targets the topoisomerase I enzyme that helps in DNA replication. As it blocks this enzyme, it prevents Cancer cells from fixing their DNA.

When cells try to divide, the blocked enzyme breaks DNA, which cannot be repaired. This triggers cell death, especially in rapidly growing Cancer cells. Irinotecan is particularly effective in cell cycle's S and G2 phases, where DNA replication actively occurs.

Cancer cells, which often have higher levels of Topoisomerase I, are more sensitive to this medicine than normal cells. Research has also suggested that it targets proteins like p53 and MDM2 to enhance its efficacy in combating Cancer cells. This significantly helps with Colorectal Cancer treatment.

Take this injection in the dose and duration your doctor administers, which depends on the condition an individual is being treated for. Do not skip the dosage; if done, inform your healthcare provider immediately. They may reschedule the appointment for the missing dose. However, you may be asked to skip the missed dose if it’s close to the next scheduled dose.

Pfizer Ltd manufactures this Campto injection.

What are the benefits of Campto 40 mg injection 2ml

Irinotecan in Campto injection is converted to SN-38, which blocks the topoisomerase I enzyme. This enzyme is required for DNA repair of cancerous cells. By blocking it, it prevents DNA copying, causing the death of these cells.

It offers benefits such as:

• Cancer medication: It treats metastatic Colorectal Cancer and is often used in combination therapies.
• Treatment of small-cell Lung Cancer (SCLC): It treats SCLC, particularly in second-line therapies.

How to take Campto 40 mg injection 2ml

Here’s how to take Campto safely and effectively:

• It is typically administered every 2 or 4 weeks.
• This injection is given intravenously (IV), i.e., into the vein for 30 to 90 minutes. A trained healthcare professional gives it. Do not self-administer if you are not trained for it.
• Take Irinotecan injection with or without food.
• Do not exceed one administration in 24 hours.

This Irinotecan injection is strictly a prescription medicine, and you should take it in the dose and duration your doctor advises.

Strengths and Substitutes

Campto 40 mg/2ml injection is available in a potent 100 mg/5ml strength. It is available in several substitutes at affordable prices at our Cheap Medicine Shop.

View All Substitutes

What are the side effects of Campto 40 mg injection 2ml

Campto injection is well-tolerated among individuals. However, in some instances, it can cause mild side effects. These settle down without any medical intervention. But consult a doctor if Campto's side effects persist or worsen.

The side effects are as follows:

• Nausea
• Loss of appetite
• Cough
• Mouth sores
• Weakness

Safety Advice

Liver disease

Inform your doctor if you ever had a history of liver conditions before using Campto injection. Dose adjustments may be needed.

Kidney impairment

Before starting Campto injection 40 mg/2ml, consult your doctor if you have kidney conditions. Dose adjustments or monitoring may be needed.

Pregnant and breastfeeding women

Campto should not be used in pregnant and breastfeeding women. This medication can harm the unborn or developing women; hence, consult your doctor.

Avoid

Alcohol’s interaction with Campto has not been well-established. Since not much information is available about how it affects the medicine’s efficacy, consult your doctor.