What is Caxeta 500 mg

Caxeta 500 mg tablet is an oral antineoplastic medication designed specifically for Colorectal Cancer treatment, Breast Cancer therapy, and Metastatic Cancer management. The active ingredient in this medicine is Capecitabine (500 mg), an FDA-approved oral chemotherapy agent that belongs to the class of antimetabolite medications used to inhibit Cancer cell growth. Sun Pharmaceuticals, India, manufactures the tablets in GMP-compliant facilities.

This cytotoxic chemotherapy acts as a prodrug that is converted to 5-fluorouracil (5-FU) in the body, particularly in tumor tissues. Once activated, it interferes with DNA and RNA synthesis in rapidly dividing Cancer cells, preventing their growth and replication.

This targeted conversion helps minimize damage to normal cells while effectively controlling tumor progression. Caxeta is used either alone or in combination with other chemotherapy medications for gastrointestinal cancer treatment and long-term cancer therapy. The typical dosage is calculated based on body surface area, usually 1250 mg per square meter twice daily for 14 days, followed by a 7-day rest period.

Common side effects include hand-foot syndrome, diarrhea, nausea, vomiting, fatigue, and decreased blood cell counts, which require careful monitoring. Before starting treatment, inform the doctor about any liver or kidney disease, heart problems, or history of blood-clotting disorders.

Regular blood tests are vital to monitor blood cell counts, liver function, and kidney function during therapy. Patients should avoid pregnancy during treatment and use effective contraception. Store Caxeta 500 mg Tablet in a cool, dry place away from sunlight and moisture at room temperature below 25°C, and keep it securely out of reach of children and pets.

What are the benefits of taking Caxeta 500 mg

Caxeta provides important therapeutic benefits for patients undergoing Cancer treatment as part of comprehensive oncology care:

• Cancer cell growth inhibition: Caxeta 500 mg effectively targets and destroys rapidly dividing cancer cells by interfering with DNA synthesis, helping shrink tumors and control Metastatic progression in Colorectal and Breast Cancer patients.
• Oral administration convenience: Unlike intravenous chemotherapy, Capecitabine is taken orally at home, offering patients greater convenience, reduced hospital visits during long-term cancer therapy without compromising treatment effectiveness.
• Targeted tumor action: The medication is preferentially converted to its active form within tumor tissues, providing more targeted Cancer cell destruction while potentially reducing damage to healthy cells compared to some traditional chemotherapy medications.
• Combination therapy effectiveness: Caxeta can be used alone or in combination with other antineoplastic medications and radiation therapy to enhance Colorectal Cancer treatment and Breast Cancer therapy outcomes, offering flexible treatment protocols tailored to individual patient needs.

How to take Caxeta 500 mg

Caxeta 500 is a prescription medication that should be taken as directed by a healthcare professional. Here are the general guidelines for taking this medication:

• Take Caxeta 500 mg twice daily, approximately 12 hours apart, typically in the morning and evening.
• Swallow the whole tablet with water without breaking or chewing.
• Take it within 30 minutes after completing a meal.
• Follow the specific 14-day on, 7-day off treatment cycle as prescribed by your oncologist for optimal tumor progression control. Do not exceed the prescribed dosage.

Strengths and Substitutes

Caxeta is currently available in a single strength option. However, you can explore these effective substitutes at Cheap Medicine Shop:

View all substitutes

What are the side effects of Caxeta 500 mg

Caxeta may cause some mild side effects. Most side effects are manageable with care and dose adjustments under medical supervision. However, consult a healthcare professional if they persist or worsen:

• Hand-foot syndrome (redness, swelling, pain)
• Diarrhea or nausea
• Fatigue or weakness
• Loss of appetite
• Mouth sores (stomatitis)
• Low blood cell counts
• Abdominal pain

Safety Advice

Liver Disease

Patients with liver disease should use Caxeta 500 with caution, as Capecitabine is metabolized by the liver. Moderate to severe liver issues may require dose reduction or more frequent monitoring. Regular liver function tests are essential during colorectal cancer treatment to detect and manage potential hepatotoxicity early.

Kidney Impairment

Caxeta tablet requires careful dosing in patients with kidney impairment, as Capecitabine and its metabolites are eliminated through the kidneys. People with moderate to severe renal dysfunction need dose adjustments based on creatinine clearance. Your doctor will monitor kidney function regularly and modify treatment accordingly to prevent serious complications.

Pregnant and Breastfeeding women

Pregnant and breastfeeding women should not use Caxeta, as Capecitabine can cause serious harm to the fetus and may pass into breast milk. Women of childbearing age must use effective contraception during Capecitabine treatment and for at least 6 months after the last dose. Discuss family planning with your oncologist before starting therapy.

Avoid

Avoid taking Warfarin or other blood thinners without close monitoring, as Caxeta 500 mg significantly increases bleeding risk through medication interactions. Do not take Caxeta in case of known DPD enzyme deficiency or are allergic to fluoropyrimidines. Avoid live vaccines during treatment. Inform the doctor about all medicines, as interactions may affect treatment efficacy or increase toxicity. Avoid sun exposure during therapy.