Extensior 0.25mg Injection Combipack

296.47
In stock
SKU CMS8994
Pack Size Price Qty Unit Price
1 Injection $296.47
$296.47
2 Injection $569.22
$284.61
3 Injection $809.36
$269.79

What is Extensior 0.25mg Injection

Extensior 0.25 mg Injection improves glycemic control in adults with Type 2 Diabetes and supports weight management in overweight or obese individuals. It is primarily used as the initiation dose in Semaglutide therapy to allow gradual dose escalation and better tolerability during the early phase of treatment.

It contains FDA-approved Semaglutide base (0.25 mg/0.5 ml) as its active ingredient, which belongs to the class of Glucagon-like Peptide-1 (GLP-1) Receptor Agonists. It works by mimicking the action of the natural GLP-1 hormone in the body.

Semaglutide activates GLP-1 receptors in the pancreas and brain, leading to glucose-dependent insulin secretion, reduced glucagon release, delayed gastric emptying, and an increased feeling of fullness. These effects help regulate blood glucose levels while also supporting appetite control and reduced caloric intake.

The Extensior injection is administered subcutaneously (under the skin) in the thigh, abdomen, or upper arm and can be taken at any time of the day, regardless of meals. Injection sites should be rotated with each use to reduce the risk of localized skin reactions.

Some patients can experience mild gastrointestinal symptoms, such as nausea or diarrhea, during the initial weeks of treatment. These effects are usually temporary and improve over time. However, seek immediate medical attention if severe or persistent abdominal pain occurs, as this may indicate Pancreatitis.

The combipack includes a prefilled pen and four sterile needles, making it suitable for once-weekly self-injection. Abbott India Limited manufactures Extensior 0.25 mg Injection at GMP-compliant facilities, adhering to strict quality standards. This injection should be stored in a refrigerator at 2°C-8°C and should not be frozen.

What are the benefits of taking Extensior 0.25mg Injection

Extensior 0.25 mg Injection supports effective management of Type 2 Diabetes and weight-related conditions through the following benefits:

  • Improved blood glucose control: Semaglutide enhances glucose-dependent insulin secretion and reduces excess glucagon release, helping maintain stable blood sugar levels after meals.
  • Supports weight management: By slowing gastric emptying, it helps reduce appetite and overall caloric intake, contributing to gradual and sustained weight loss when combined with lifestyle changes.
  • Better metabolic regulation: It improves the body’s ability to utilize glucose efficiently, which can contribute to overall metabolic health and reduced insulin resistance over time.
  • Cardiovascular risk reduction: Semaglutide has been shown to lower the risk of major events, including heart attack and Stroke, particularly in individuals with existing risk factors.

How to take Extensior 0.25mg Injection

Extensior 0.25 mg Injection is a prescription medication that must be used as directed by a healthcare professional. It should not be administered without proper training. Here are the general guidelines:

  • Administer one injection once a week, on the same chosen day each week.
  • Allow the pen to reach room temperature, then inject under the skin of the thigh, upper arm, or abdomen, and rotate the injection site with each dose. It should not be administered in a muscle or vein.
  • The injection can be administered at any time of the day, with or without food.
  • Do not administer more than one dose within any seven-day period or administer more than the recommended dosage.

Strengths and Substitutes

Extensior Injection is currently available in a single strength at Cheap Medicine Shop. However, the following effective alternatives are available:

Wegovy 0.5 mg $270.58/injection
Wegovy 0.25 mg $270.58/injection
Wegovy 1 mg $270.58/injection

View all substitutes

What are the side effects of Extensior 0.25 mg Injection

The Semaglutide Injection can cause some side effects, particularly during the initial weeks of therapy. Most are mild and temporary and will subside as the body adjusts. However, consult a healthcare professional if they persist or worsen:

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal discomfort
  • Decreased appetite
  • Injection site reactions

Safety Advice

Liver Disease

Extensior 0.25 mg Injection should be used with caution in the case of mild to moderate liver disease. It is not recommended in cases of severe liver impairment. A doctor should be informed of any liver conditions before initiating treatment to ensure safety.

Kidney Impairment

Semaglutide requires caution in patients with kidney disease due to gastrointestinal side effects such as vomiting and diarrhea, which can contribute to dehydration and further strain the kidneys. Inform a doctor about any existing kidney conditions before starting this medication, and seek medical attention promptly if dehydration symptoms occur during treatment.

Pregnant and Breastfeeding women

Extensior 0.25 mg Injection is not recommended during pregnancy or while breastfeeding. Semaglutide has shown potential for fetal harm in preclinical studies, and its safety has not been confirmed in human pregnancies. If pregnancy occurs during treatment, stop the injection and consult a doctor without delay.

Avoid

Do not use Extensior 0.25mg Injection in cases of known hypersensitivity to Semaglutide or any inactive ingredients in the formulation. It is contraindicated in people with Type 1 Diabetes or cancers like Medullary Thyroid Carcinoma and Multiple Endocrine Neoplasia Syndrome Type 2 (MEN 2). Disclose all current medications to a doctor before starting treatment, especially insulin and sulfonylureas, as their concurrent use may increase the risk of Hypoglycemia (low blood sugar).

FAQs

How often should Extensior 0.25 mg Injection be taken?

Extensior Injection is given once a week, on a fixed day chosen at the start of treatment. It can be taken at any time of the day and does not need to be timed around meals. However, people who experience nausea should eat light meals to better manage their symptoms.

What should I do if I miss a dose of Extensior 0.2 5mg Injection?

If a dose is missed and at least 2 days remain before the next scheduled injection, take the missed dose as soon as possible. If fewer than two days remain, skip the missed dose and continue with the usual weekly schedule. Never administer two doses within 48 hours.

How should the prefilled pen be stored after first use?

After the first use, the prefilled pen can be stored at room temperature below 30°C for up to 6 weeks. It should not be returned to the refrigerator once in use. Keep it away from direct sunlight and heat.

Can Extensior 0.25 mg Injection be taken with other Diabetes medicines?

Yes, Extensior can be used alongside other antidiabetic medications, but only under medical supervision. When combined with insulin or sulfonylureas, the risk of Hypoglycemia increases, and a dose adjustment of the existing medications may be required. Always inform a doctor of all medications being taken before starting this injection.

Is Extensior 0.25mg Injection safe during pregnancy?

No, Extensior 0.25 mg is not safe during pregnancy. Animal studies have indicated that Semaglutide can adversely affect fetal development, and its safety in human pregnancies has not been established. If pregnancy occurs during treatment, stop the injection and seek immediate medical advice.

Does Extensior 0.25mg Injection cause low blood sugar on its own?

No, Extensior injection is unlikely to cause Hypoglycemia because Semaglutide only stimulates insulin release in response to elevated blood glucose. The risk of low blood sugar becomes significant when this medication is used with insulin or sulfonylureas. For safety, monitor blood glucose regularly and report issues to a doctor immediately.

Who should not use Extensior 0.25mg Injection?

Extensior Injection is not suitable for individuals with Medullary Thyroid Carcinoma or MEN 2 Syndrome, or those with a known allergy to Semaglutide. It should also not be used by individuals with Type 1 Diabetes or during pregnancy and breastfeeding.

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