Fortum 500 Mg Injection
| Pack Size | Price | Qty | Unit Price |
|---|---|---|---|
| 5 Injection | $38.10 | $7.62 | |
| 10 Injection | $74.70 | $7.47 | |
| 15 Injection | $110.90 | $7.39 |
What is Fortum 500 mg Injection
Fortum 500 mg Injection is a sterile injectable antibiotic containing the FDA-approved active ingredient Ceftazidime (500 mg). GlaxoSmithKline Pharmaceuticals Ltd manufactures this injection in GMP-compliant facilities.
Ceftazidime belongs to the third-generation cephalosporin class of antibiotics. It is used to treat moderate to severe bacterial infections, including lower respiratory tract infections such as Pneumonia, Urinary Tract Infections (UTIs), skin and soft tissue infections, Meningitis, bone and joint infections and intra-abdominal infections.
It works by binding to Penicillin-binding Proteins (PBPs) on the bacterial cell wall, thereby disrupting its structural integrity and leading to bacterial cell death. This bactericidal mechanism is effective against a broad range of gram-negative organisms and select gram-positive bacteria, with particularly strong activity against Pseudomonas aeruginosa, Enterobacteriaceae, Haemophilus influenzae, and Neisseria species.
The injection is administered intravenously or intramuscularly as directed by a prescribing physician, with the dose and frequency determined by the type, severity, and location of the infection. Some of its common side effects include diarrhea, nausea, injection site reactions, and skin rash.
Before administering Fortum 500 mg Injection, inform a doctor of any history of allergy to cephalosporins, penicillins, or other beta-lactam antibiotics, kidney disease, seizure disorders, or concurrent use of nephrotoxic medications, as these may require dose modification or additional monitoring. Store the vials below 25°C, protected from light, and use the reconstituted solution immediately or within the timeframe specified in the packaging.
What are the benefits of using Fortum 500 mg Injection
Fortum 500 mg Injection provides targeted antibacterial benefits for patients with serious infections requiring parenteral therapy. Some of them include:
- Effective against several bacterial infections: It is used to treat conditions such as Pneumonia, Sepsis (bloodstream infections), UTIs, and intra-abdominal infections, including those caused by difficult-to-treat organisms such as Pseudomonas aeruginosa.
- Active in resistant infections: Its stability against beta-lactamase enzymes allows it to remain effective in infections where some antibiotics may not work due to resistance.
- Flexible administration options: It can be given intravenously or intramuscularly, allowing treatment to be tailored based on infection severity and clinical setting.
How to use Fortum 500 mg Injection
Fortum Injection is a prescription medication for clinical use only and is administered under the supervision of a qualified healthcare professional. General administration considerations include:
- The dose route, whether intravenous or intramuscular (IV or IM), and frequency are determined by the doctor based on infection severity and the patient’s kidney function.
- The injection is reconstituted with a suitable diluent according to prescribing guidelines, and the prepared solution is used promptly.
- For intravenous use, it is given as a slow injection or infusion over the recommended time under medical supervision.
- The total course length is decided by the doctor based on clinical response, and completing the full prescribed course is essential for effective treatment. It should not be self-administered, and no dose adjustments should be made without medical consultation.
Strengths and Substitutes
Fortum Injection is available in multiple strength alternatives at Cheap Medicine Shop. You can consider the following alternatives:
| Fortum 250 mg Injection | $4.01/injection |
| Fortum 2 gm Injection | $45.03/injection |
What are the side effects of Fortum 500 mg Injection
Like any medication, Fortum 500 Injection can cause some side effects that are generally mild and transient. However, consult a healthcare professional if they persist or worsen:
- Diarrhea
- Nausea or vomiting
- Injection site pain, redness, or swelling
- Skin rash or itching
- Headache
- Elevated liver enzyme levels
Safety Advice
Fortum 500 mg Injection should be used with caution in patients with liver disease. Although Ceftazidime is not significantly metabolized in the liver, the medicine may affect liver enzymes or function. Inform a doctor of any liver conditions before initiating treatment so the overall clinical picture can be considered.
Individuals with kidney disease should use Fortum Injection with caution. Ceftazidime is almost entirely eliminated through the kidneys, and reduced function leads to medicine accumulation that increases the risk of neurotoxicity. It is vital to assess kidney function before initiating therapy to ensure safety.
Fortum 500 mg Injection should be used during pregnancy only when clearly necessary and under medical supervision. While animal studies have not demonstrated direct harm to the fetus, it is vital to weigh the benefits and risks before treatment. Ceftazidime passes into breast milk in small amounts. So, it is usually safe if prescribed. However, breastfeeding women should consult a doctor before use.
Do not use Fortum Injection in patients with known hypersensitivity to Ceftazidime, other cephalosporins, or any component of the formulation. Use with caution in patients with a documented penicillin allergy, as cross-reactivity between penicillins and cephalosporins, though uncommon, is possible. Avoid concurrent use of nephrotoxic medications such as Aminoglycosides or loop diuretics without careful monitoring of kidney function, as the combination can increase the risk of kidney damage.
FAQs
Can Fortum 500 mg Injection cause diarrhea?
Yes, diarrhea is one of the more commonly reported side effects of Ceftazidime. It is usually mild and resolves after completing the course. However, if diarrhea is severe, persistent, or accompanied by cramping and blood in the stool, inform a doctor promptly.
How long does Fortum 500 mg Injection take to work?
Ceftazidime begins working immediately after administration and rapidly reaches therapeutic concentrations in infected tissues via the intravenous or intramuscular route. Clinical improvement in symptoms such as fever and pain is typically noticeable within 48 to 72 hours of starting treatment, though the full prescribed course must always be completed.
Is Fortum 500 mg Injection effective against Pseudomonas infection?
Yes, Ceftazidime has well-established and reliable activity against Pseudomonas aeruginosa, making Fortum 500 mg Injection one of the preferred antibiotic options for infections caused by this organism. It is commonly used in the treatment of Pseudomonas-related Pneumonia, UTIs, and wound infections, particularly in hospital and immunocompromised patient settings.
Can Fortum 500 mg Injection be used in patients with kidney problems?
Fortum 500 mg Injection can be used in patients with kidney disease, but requires careful dose adjustment. As Ceftazidime is primarily excreted by the kidney, impaired kidney function significantly reduces its clearance and can lead to medicine accumulation and toxicity. Renal function should be assessed before and monitored throughout treatment.
Can Fortum 500 Mg Injection be used for Meningitis?
Yes, Ceftazidime has good penetration into the cerebrospinal fluid and is used in the treatment of bacterial Meningitis, particularly in cases caused by gram-negative organisms, including Pseudomonas aeruginosa. Its use for Meningitis is determined by a doctor based on culture results and clinical presentation.
How is Fortum 500 mg Injection administered?
Fortum 500 mg Injection is administered by a qualified healthcare professional, either intravenously or intramuscularly, following reconstitution of the vial with the appropriate diluent. The intravenous route is preferred for severe infections to ensure rapid and complete drug delivery. The dose, frequency, and route are determined by the prescribing physician.
Is Fortum 500 mg Injection safe for children?
Yes, Ceftazidime is used in children, including neonates and infants, for serious bacterial infections. Dosing in children is calculated based on body weight. A doctor will determine the appropriate dose and frequency for each child based on age, weight, the type of infection, and overall clinical status.
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