What is Nebracin DM

Nebracin DM 3 gm is a combination ophthalmic medication designed to treat bacterial eye infections accompanied by inflammation, including Conjunctivitis, postoperative eye inflammation, and other mixed eye infections requiring both antibiotic and anti-inflammatory action. This medicine contains FDA-approved active ingredients: Dexamethasone (0.1% w/v), a corticosteroid, and Tobramycin (0.3% w/v), an aminoglycoside antibiotic. Sunways, India, manufactures the ointment in GMP-compliant facilities.

This ophthalmic combination therapy works through dual action. Tobramycin is a broad-spectrum antibiotic that effectively eliminates bacteria by inhibiting protein synthesis, targeting both gram-positive and gram-negative organisms responsible for eye infections. Dexamethasone is a potent corticosteroid that reduces eye inflammation, redness, swelling, and discomfort by suppressing the immune response and inflammatory mediators. Together, they treat infection while controlling inflammatory symptoms.

The typical dosage is a small amount (approximately half an inch ribbon) of ointment applied to the affected eye(s) every 4-6 hours initially, with frequency adjusted based on severity and response. Treatment duration usually ranges from 7 to 14 days as prescribed by your ophthalmologist. Common side effects include temporary stinging or burning, blurred vision, eye irritation, and increased intraocular pressure with prolonged use.

Before using Nebracin DM, inform your doctor about any viral or fungal eye infections, Glaucoma, cataracts, or allergies to aminoglycosides or corticosteroids. This medication should not be used for viral infections, such as Herpes, or for prolonged periods without medical supervision.

Individuals who use contact lenses should remove them before application. Store the ointment in a dry place at room temperature below 25°C, and store it out of reach of children. Once opened, use within 4 weeks.

What are the benefits of using Nebracin DM

The ointment provides important therapeutic benefits for patients with bacterial eye infections accompanied by inflammation:

• Treats bacterial infections: Tobramycin effectively eliminates a wide range of bacteria causing eye infections, including Staphylococcus and Pseudomonas species.
• Reduces inflammation: Dexamethasone quickly controls eye redness, swelling, and discomfort associated with infection and postoperative conditions.
• Dual-action formula: The combination addresses both infection and inflammation simultaneously, providing effective treatment for mixed eye infections.
• Postoperative care: It is suitable for managing inflammation and preventing infection after eye surgery, promoting faster healing and comfort.

How to use Nebracin DM

It is a prescription eye ointment that should be used as directed by a healthcare professional. Here are the general guidelines:

• Apply approximately half an inch of ribbon of the ointment to the affected eye every 4-6 hours or as prescribed by your ophthalmologist.
• Wash your hands thoroughly, tilt your head back or lie down, pull the lower eyelid to create a pocket, and squeeze the ointment into the pocket. Close your eyes gently and roll your eyeball to distribute the ointment evenly.
• Do not use it for more than 10-14 days without medical supervision due to corticosteroid-related risks.

Strengths and Substitutes

Nebracin DM is available in the following formulation for bacterial eye infection and inflammation treatment at Cheap Medicine Shop:

View all substitutes

What are the side effects of Nebracin DM

Like any medication, Nebracin DM 3 gm may cause some side effects. Most of these are mild and temporary, resolving as treatment continues. However, consult a healthcare professional if they persist or worsen:

• Temporary stinging or burning
• Blurred vision
• Eye irritation or discomfort
• Increased eye redness
• Eye itching
• Delayed wound healing

Safety Advice

Liver Disease

Patients with liver disease can generally use this ointment safely, as topical ophthalmic application results in minimal systemic absorption. However, inform the healthcare provider about any liver conditions. While systemic effects are rare with eye ointment, patients using it for extended periods should inform their doctor.

Kidney Impairment

It should be used with caution in patients with kidney impairment, particularly with prolonged use. While topical application minimizes systemic absorption, aminoglycosides like Tobramycin can be nephrotoxic if absorbed. Inform the ophthalmologist of any kidney problems to ensure appropriate monitoring during treatment.

Pregnant and Breastfeeding women

Pregnant and breastfeeding women should use this ointment only under strict medical supervision. While topical application results in minimal systemic absorption, both corticosteroids and aminoglycosides have been associated with potential concerns. Discuss the safety with a healthcare provider before use.

Avoid

Avoid using Nebracin DM for viral eye infections like Herpes Simplex Keratitis, as corticosteroids can worsen viral infections. Do not use it in cases of fungal eye infections or ocular Tuberculosis. Patients with Glaucoma should use it with extreme caution due to the risk of increased intraocular pressure. Patients allergic to aminoglycosides or corticosteroids should not use this medication.