Nexvir Z Tablet
What is Nexvir Z Tablet
Nexvir Z Tablet is a fixed-dose antiretroviral medicine used to treat HIV-1 infection. It contains FDA-approved active ingredients: Lamivudine 150 mg, Zidovudine 300 mg, and Nevirapine 200 mg, which work together to control viral replication and strengthen the immune system.
Lamivudine and Zidovudine belong to the NRTI (Nucleoside Reverse Transcriptase Inhibitor) class, while Nevirapine is an NNRTI (Non-nucleoside Reverse Transcriptase Inhibitor). Nexus India manufactures Nexvir Z under GMP-certified quality standards.
Lamivudine and Zidovudine act as false building blocks for viral DNA, causing chain termination and stopping HIV from multiplying. Nevirapine binds to a different site on the HIV-1 enzyme, further blocking viral replication. This combination is used as part of first-line or alternative HIV treatment in adults and some older children, according to medical guidelines.
Nexvir Z is usually taken one tablet twice daily, with or without food. Always follow your HIV specialist's instructions. Frequent blood tests are needed to monitor liver function, blood counts, viral load, and CD4 levels. If you miss a dose, take it as soon as you remember unless it is close to the next dose. Do not double the dose. In case of overdose, seek urgent medical care and bring the medicine pack with you.
Common side effects of this medication are nausea, headache, and mild rash. Seek immediate help for severe rash, jaundice, breathing difficulty, extreme weakness, or signs of liver damage. Use with caution in liver disease, anemia, pregnancy, and renal impairment. Nevirapine may interact with hormonal contraceptives, antifungals, and some HIV drugs.
Store Nexvir Z below 30°C, away from moisture and heat.
What are the benefits of taking Nexvir Z Tablet
Nexvir Z is a combination antiretroviral medicine designed to manage HIV-1 infection effectively. It helps control the virus and supports the immune system for better overall health. Key Nexvir Z tablet benefits are:
- Stops HIV multiplication: Lamivudine, Zidovudine, and Nevirapine block the enzymes HIV needs to replicate, slowing the virus’s spread.
- Boosts the immune system: By controlling HIV, it helps increase CD4 cells, strengthening your body’s ability to fight infections.
- Prevents complications: Reduces the risk of developing AIDS and other opportunistic infections, improving health and quality of life.
- Manages HIV/AIDS: Helps control chronic infection and prevents progression to severe stages, though it is not a cure.
How to take Nexvir Z Tablet
Nexvir Z Tablet is a prescription medication that patients should take under a healthcare professional's guidance. At the same time, some general guidelines should be followed to achieve consistent results. They are:
- Take the dose as prescribed by your doctor.
- Can take the tablets with or without food. Do not miss or exceed the dose, which will affect the recovery process.
- Consume the tablet fully with water. Do not crush, chew, or break it.
- Take it at the same time every day for consistent medication levels in your body.
Strengths and Substitutes
Currently, Cheap Medicine Shop stocks only one strength of Nexvir Z Tablet. However, substitutes are available that can be suitable based on your medical needs. Always consult a doctor before use.
| Duovir-N (150+200+300) mg | $9.00/10 pills |
| Lazid N Tablet | $21.48/bottle |
What are the side effects of Nexvir Z Tablet
Nexvir Z tablets are generally well-tolerated when taken as prescribed under the guidance of a healthcare professional. However, you may still experience some side effects, especially at the beginning of the treatment. Some common Nexvir Z tablet side effects are:
- Headache
- Fatigue
- Nausea
- Anemia
- Dizzines
- Mild rash
They are usually mild and will go away as your body adjusts to the medication. However, if they continue or worsen, consult a doctor immediately.
Safety Advice
Patients with mild liver disease should use or take the medication with caution and close monitoring of their liver function. However, use is not recommended in moderate to severe liver disease because the Nevirapine component can cause serious and sometimes fatal hepatitis or liver failure.
Caution while using Nexvir Z tablet for patients with kidney disease, as the kidneys primarily clear the NRT inhibitors, and their dysfunction may lead to slow clearance, which can increase the risk of side effects.
Pregnant women and nursing mothers should consult a doctor before opting for this medication. Although animal studies have not shown any harmful effects on the fetus during pregnancy, there are limited human studies. During breastfeeding, limited human data suggest that the medication can pass into the breast milk and harm the baby. The doctor will only prescribe this medication if the benefits outweigh the potential risks.
Do not take this medication if you are allergic to any of the antiretroviral agents. Avoid consuming alcohol; it can increase liver and bone marrow toxicity. Also, avoid driving or other tasks that require attention if you experience dizziness, fatigue, or weakness.
FAQs
Is there an antidote for Nexvir Z overdose?
No, there is no specific antidote for Nexvir Z Tablet overdose. If an overdose occurs, medical care should be sought immediately. Treatment is supportive, meaning doctors will monitor vital signs, manage symptoms, and provide interventions as needed to prevent complications.
How should Nexvir Z Tablet be stored?
Store Nexvir Z Tablet in a cool, dry place below 25 °C, away from direct sunlight, heat, and moisture. Keep it in its original blister or container and always out of reach of children. Do not use the tablets after the expiry date.
Can I crush or split the tablets?
No, you should not crush, split, or break Nexvir Z tablets. Doing so can alter how the medicine is absorbed, affect its effectiveness, change the taste, and make it harder to follow your prescribed regimen properly. Always swallow the tablet whole with water.
Can it interact with antifungals or antibiotics?
Yes, Nexvir Z can interact with certain antifungals, such as Fluconazole or Ketoconazole and antibiotics such as Rifampicin, which may alter Nevirapine levels or effectiveness. Some antibiotics can also affect heart rhythm. Always inform your doctor about all medications to ensure safe dosing and proper monitoring.
Can Nexvir Z Tablet reduce the risk of opportunistic infections?
Yes, by controlling HIV and boosting CD4 cell counts, Nexvir Z helps strengthen your immune system. This reduces the likelihood of opportunistic infections, which are more common in people with weakened immunity, thereby protecting overall health and improving quality of life.
Why is triple-drug therapy better than single drugs?
Yes, triple-drug therapy like Nexvir Z is more effective than monotherapy. It prevents HIV resistance by targeting the virus at multiple points, achieves better viral suppression, and promotes stronger immune recovery, increasing CD4 counts and reducing the risk of opportunistic infections.
How does Nexvir Z Tablet help prevent AIDS?
Nexvir Z controls HIV by suppressing viral replication and boosting CD4 cell counts, which strengthens your immune system. Keeping the virus under control reduces the risk of immune system failure and the development of AIDS, helping prevent opportunistic infections and serious HIV-related complications.
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