Olparib Tablet
| Pack Size | Price | Qty | Unit Price |
|---|---|---|---|
| 60 Tablet/s | $281.00 | $4.68 | |
| 120 Tablet/s | $533.90 | $4.45 | |
| 180 Tablet/s | $758.70 | $4.22 |
What is Olparib
Olparib is an anticancer medication primarily used to treat and maintain advanced cases of ovarian, breast, pancreatic, and prostate cancers. It contains Olaparib (100 mg) as the active ingredient, and Glenmark Pharmaceuticals Ltd manufactures it.
Olaparib belongs to the class of PARP (Poly-ADP Ribose Polymerase) inhibitors. It targets cancer cells with BRCA mutations by blocking PARP enzymes responsible for DNA repair. This disruption leads to DNA damage buildup and, ultimately, cancer cell death.
Olparib is recommended for adult patients with certain types of advanced cancers, especially those who have a BRCA mutation and have previously responded to platinum-based chemotherapy.
Common side effects of this drug may include nausea, vomiting, fatigue, and anemia. Drugs like Rifampicin, Carbamazepine, Phenytoin, and herbal supplements such as St. John's Wort can reduce the effectiveness of Olparib. Additionally, patients should also avoid grapefruit juice and Seville oranges, as they can elevate Olaparib levels in the blood, raising the risk of side effects. Patients with liver or kidney conditions should use it with caution.
Always consult your doctor and inform them about any prescription drugs, over-the-counter medications, or supplements that you are using to avoid harmful interactions.
What are the benefits of taking Olparib
Olparib offers several significant benefits for patients with certain advanced cancers, particularly those with BRCA mutations or related DNA repair defects.
- Olparib is a PARP inhibitor, which means it specifically targets cancer cells that have difficulty repairing their DNA (such as those with BRCA1 or BRCA2 mutations).
- By blocking the PARP enzyme, Olparib causes these cancer cells to accumulate DNA damage and die, sparing most healthy cells.
- Olaparib significantly increases the time patients live without their cancer worsening (progression-free survival), especially in ovarian, breast, pancreatic, and prostate cancers with relevant genetic markers.
- It is used as maintenance therapy after initial cancer treatments (like chemotherapy) have successfully shrunk tumors, helping to keep the cancer from returning or progressing for an extended period.
How to take Olparib
Patients should take this prescription-based medication per the doctor's instructions. Here are some general guidelines.
- Take two tablets twice a day.
- Take it with or without food.
- Swallow the whole tablet with water. Do not crush or chew it.
- Consult a doctor for any possible dose adjustments.
Strengths and Substitutes
No strengths of Olparib are available at Cheap Medicine Shop. However, there are substitutes with the same salt available
| Lupiparp 150 Tablet | $114.40/10 tablets |
| Lynparza 50 Mg Capsule | $193.50/10 tablets |
| Lynparza 100 mg Tablet | $1523.30/10 tablets |
What are the side effects of Olparib
The side effects of Olparib Tablet are:
- Anemia
- Nausea
- Vomiting
- Fatigue
- Weight loss
- Cough
They are temporary and will disappear as the body adjusts to the medication. However, if the symptoms continue or worsen, consult a doctor immediately.
Safety Advice
The medication is typically safe for patients with mild liver disease, with no possible dosage adjustments. However, as a precaution, please consult a doctor before taking it. Caution is advised for patients with moderate to severe liver disease.
Olaparib is generally safe for patients with kidney impairment. However, as a precautionary measure, consult a healthcare professional before use. Caution is advised for patients with moderate to severe kidney impairment.
This medication is typically not advised during pregnancy due to potential risks to the developing fetus. It's essential to talk to a doctor for suitable treatment options. It is not known how much Olaparib may be present in breast milk or how it could affect a breastfeeding infant, so patients should always seek medical advice before use.
Avoid the medication if you are allergic to Olparib. Also, avoid consuming grapefruit juice and Seville oranges, as they can raise the blood levels of Olaparib and the risk and/or severity of side effects.
FAQs
Can Olparib cause changes in my blood cell counts?
Yes, Olparib can significantly change your blood cell counts. It commonly leads to decreases in red blood cells (Anemia), white blood cells (Leukopenia and Neutropenia), and platelets (Thrombocytopenia). These changes may result in symptoms such as fatigue, weakness, increased risk of infections, and a tendency to bruise or bleed more easily.
How can I manage the common side effects of Olparib?
There are ways to manage and prevent the common side effects of Olparib. For nausea or vomiting, your doctor may prescribe anti-nausea medication. Eating small, frequent meals and avoiding fatty or spicy foods can help. For fatigue, get plenty of rest and stay hydrated. Incorporate good oral hygiene and avoid spicy or acidic foods to prevent mouth sores.
How long will I need to take Olparib?
The duration of treatment with Olparib depends on your cancer type, response to therapy, and side effects. Your doctor will monitor your progress and determine how long you should continue taking the medication.
Can Olparib affect my mouth or throat?
Olparib can cause a sore mouth, throat, or mouth ulcers, increasing your risk of mouth infections. Use a soft toothbrush, maintain good oral hygiene, and avoid alcohol, tobacco, and irritating foods. Tell your doctor if you develop mouth sores for appropriate treatment.
What should I do if I get a rash while taking Olparib?
Olparib may cause an itchy, raised, or red rash. If this happens, inform your healthcare provider. They can recommend skin care or prescribe creams to help manage the rash.
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