Myostigmin 0.5 Mg Injection 1ml
| Pack Size | Price | Qty | Unit Price |
|---|---|---|---|
| 20 Injection | $20.42 | $1.02 | |
| 40 Injection | $38.64 | $0.97 | |
| 60 Injection | $54.60 | $0.91 |
What is Myostigmin 0.5 mg
Myostigmin 0.5 mg Injection is used to treat Myasthenia Gravis and, at the same time, to reverse the effects of non-depolarizing neuromuscular blockers post-surgery. Its active ingredient, Neostigmine (0.5 mg/ml), is FDA-approved and helps improve muscle strength and movement.
Neostigmine belongs to the Cholinesterase inhibitor (anticholinesterase) class and is manufactured by Neon Laboratories Ltd., a reputable pharmaceutical company, in accordance with GMP standards.
Neostigmine inhibits acetylcholinesterase, increasing acetylcholine at the neuromuscular junction and enhancing muscle contraction. Myostigmin is mainly used for myasthenia gravis, postoperative paralytic ileus, urinary retention, reversal of muscle relaxants (with atropine), and orthostatic hypotension.
The injection is administered slowly via IV or IM under medical supervision. Typical doses for Myasthenia Gravis range from 0.5 mg to 2.5 mg every 2 to 4 hours, while reversal of neuromuscular blockade is 0.5 mg to 2 mg IV with atropine. Dosage is individualized based on patient response.
An overdose can cause a cholinergic crisis with symptoms like muscle weakness, bradycardia, and excessive salivation. Missed doses are rare under supervision. Always follow your doctor's instructions.
Common side effects of Myostigmin are nausea, vomiting, diarrhea, abdominal cramps, salivation, bradycardia, and muscle twitching. Seek urgent help for severe bradycardia, breathing difficulty, or signs of cholinergic crisis.
Avoid use in mechanical bowel or urinary obstruction, severe bradycardia, or asthma. Use caution in epilepsy, Parkinson's, hypotension, or peptic ulcer. Medicine interactions include beta-blockers, procainamide, quinidine, and aminoglycosides. Always administer with atropine to reduce muscarinic effects.
Store Myostigmin at 25-30°C, protected from light, in its original carton, and keep out of reach of children.
What are the benefits of taking Myostigmin 0.5 mg
Myostigmin 0.5 mg Injection is used to improve muscle strength and restore normal muscle function in certain medical conditions. It works quickly to support recovery and ease daily activities affected by muscle weakness. Benefits of taking Myostigmin 0.5 mg are:
- Improves muscle strength in Myasthenia Gravis: Helps individuals with muscle weakness perform daily activities such as swallowing, speaking, and moving more easily.
- Reverses effects of muscle relaxants: Restores normal muscle function after surgeries where muscle relaxants were used.
- Supports postoperative recovery: Helps relieve post-surgery issues such as difficulty emptying the bladder (urinary retention) and delayed bowel movements (paralytic ileus).
How to use Myostigmin 0.5 mg
Myostigmin 0.5 mg is a prescription medicine that patients should take under the supervision of a healthcare professional. However, here are some general guidelines for proper application:
- It should always be administered by a doctor or a nurse.
- It can be administered in three ways: subcutaneously (SC), that is, under the skin; intramuscularly (IM), that is, into a muscle; and intravenously (IV), that is, into the vein
- Do not try to self-administer it.
- Always follow the prescribed dose.
Strengths and Substitutes
Currently, Cheap Medicine Shop stocks different substitutes for this injection. They can be suitable depending on your medical needs. Always consult a doctor before opting for these injections.
| Tilstigmin 0.5 mg Injection | $1.61/injection |
| Neomine 0.5 mg Injection | $0.14/injection |
What are the side effects of Myostigmin 0.5 mg
Myostigmin 0.5 mg is generally well-tolerated when administered under the supervision of a doctor or a nurse. However, as with any other medication, you may still experience mild, temporary side effects. Such common side effects are:
- Nausea
- Vomitting
- Diarrhea
- Abdominal cramps
- Muscle twitching
- Slow heart rate
However, if they continue or worsen, consult a doctor as soon as possible.
Safety Advice
Myostigmin 0.5 mg is generally safe when taken as prescribed. However, consult a doctor for safe and effective use.
The kidneys primarily clear Neostigmine from the body, and its dysfunction can slow this process, leading to a buildup of the medicine. This can increase the risk of side effects. Consult a doctor before opting for this injection.
Limited studies are available about its interaction with pregnancy and its potential harm to the fetus. Consult a doctor before you use it. Similarly, limited clinical data suggest that this medication can be acceptable in breastfeeding mothers to treat Myasthenia Gravis. However, consult a doctor before using it.
Do not take this injection if you are allergic to Neostigmine. Avoid alcohol, as it can raise the risk of excessive drowsiness.
FAQs
Is Neostigmine a muscle relaxer?
No, Neostigmine is not a muscle relaxer. It actually helps your muscles contract by increasing acetylcholine levels, thereby improving muscle strength and reversing the effects of muscle relaxants administered during surgery.
How long does Neostigmine take to work?
Neostigmine in Myostigmin 0.5 mg works quickly after injection. With IV use, effects start within 1 minute and peak in 7 to 10 minutes. IM or SC routes take 10-30 minutes. Its effects last 20 to 55 minutes for reversal and up to 2 to 4 hours for Myasthenia Gravis.
Can Myostigmin 0.5 mg be frozen?
No, Myostigmin should not be frozen. Freezing can damage the medicine and reduce its effectiveness. Store it at room temperature, protected from light, and keep it in its original packaging as directed.
What does Neostigmine do to the heart?
Neostigmine can slow your heart rate by increasing acetylcholine levels. This may cause bradycardia (slow heartbeat), especially at higher doses, which is why it's often given with atropine to protect your heart.
What are the first signs of Myasthenia Gravis?
You may first notice muscle weakness that worsens with activity, especially drooping eyelids, double vision, difficulty chewing or swallowing, slurred speech, and weakness in the arms or neck.
Does Neostigmine affect blood pressure?
Yes, Neostigmine can lower your blood pressure by slowing the heart rate and increasing vagal tone. This may cause dizziness or lightheadedness, especially if you already have Low Blood Pressure.
Can Myostigmin cause muscle weakness?
Yes, if you receive too much Myostigmin, it can cause muscle weakness due to a cholinergic crisis. This happens when acetylcholine levels become too high. Always use it under medical supervision.
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