Pegadria 20 Mg Injection
| Pack Size | Price | Qty | Unit Price |
|---|---|---|---|
| 2 Injection | $306.56 | $153.28 | |
| 4 Injection | $598.41 | $149.60 | |
| 6 Injection | $882.90 | $147.15 |
What is Pegadria 20 mg Injection
Pegadria 20 mg Injection is an Anticancer medication used to treat various types of Cancer characterized by uncontrolled cell growth and division. It is primarily used as adjuvant Chemotherapy for Breast Cancer, especially in cases involving axillary lymph nodes. Also, it treats Neuroblastoma and Wilms' tumor, both of which are Cancers affecting children.
Intas Pharmaceuticals Ltd manufactures Pegadria 20. The active ingredient, Doxorubicin, belongs to the class of Anthracycline Topoisomerase inhibitors. It works by inhibiting the Topoisomerase II enzyme, disrupting DNA base pairs, and ultimately destroying DNA and RNA synthesis. Thus, it stops Cancer cell growth.
This medication may cause certain side effects, including nausea, headache, and abdominal pain. Most of these side effects resolve over time but may require medical attention if they persist. Administration should only be done by a trained doctor, and the dosage is determined based on your health condition.
Pegadria 20 injection should be avoided if there is an allergy to it or its components. It is contraindicated in people with severe heart conditions, recent Myocardial Infarction, and severe drug-induced Myelosuppression.
People with cardiovascular conditions, liver or kidney disease, or those taking certain medications should inform their doctor. Additionally, it can cause embryo-fetal toxicity, so women in the pregnant or breastfeeding stages should consult their doctor before use.
What are the benefits of Pegadria 20 mg Injection
Pegadria injection contains Doxorubicin, which is used to treat a variety of Cancers, including:
- Breast Cancer: It is effective in managing advanced Breast Cancer and is often used as part of adjuvant Chemotherapy.
- Ovarian Cancer: It is used to treat Ovarian Cancer, especially where the Cancer has spread.
- AIDS-related Kaposi’s Sarcoma: A Cancer that affects individuals with HIV/AIDS, forming in the lining of lymph and blood vessels.
- Other Cancers: It is also used to treat Bladder Cancer, Hodgkin's Lymphoma, Acute Lymphocytic Leukemia, and Neuroblastoma.
Doxorubicin, the active ingredient in Pegadria, belongs to the class of Anthracycline Topoisomerase inhibitors. It intercalates DNA base pairs, disrupting the Topoisomerase II enzyme. This disruption causes the double helix DNA to uncoil, destroying DNA and RNA synthesis. As a result, Cancer cell growth is significantly slowed or stopped.
How to take Pegadria 20 mg Injection
A doctor or nurse administers this 20 mg injection. Your doctor knows your condition and can prescribe the ideal dosage and the best time for this injection. For the best results, take the medicine in the following ways:
- Your doctor decides the appropriate dosage and schedules the best time to take this medicine.
- Your doctor or nurse typically injects this injection intravenously. To reduce the severity of the risks, do not self-administer the medicine.
- Consult your doctor about whether you can take it with or without food.
- Your doctor will decide the frequency of this injection, usually daily or as your doctor advises, based on your response.
Strengths and substitutes
Pegadria 20 Injection is available in various strengths, and your doctor will decide on the appropriate dosage based on your Cancer type and response.
The Cheap Medicine Shop only offers Pegadria 20 mg Injection. However, for the best results, consider reliable Doxorubicin substitutes.
| $49.50 / Injection | |
| $151.20 / Injection |
What are the side effects of Pegadria 20 mg Injection
While Pegadria is effective in treating Cancer, it can cause certain side effects in some people. These side effects are mild, temporary, and well-tolerated. They also disappear as your body adjusts to the new medicine or its adjusted dosage.
Some common Pegadria 20 side effects are as follows:
- Nausea and Vomiting
- Hair Loss
- Abdominal pain
- Mouth Sores
- Allergic Reactions
- Back pain
- Loss of appetite
If these side effects persist for longer, worsen, or affect your daily routine, consult your doctor and seek immediate treatment.
Safety Advice
Pegadria injection should be used with caution in people with liver impairment. However, it is contraindicated in people with severe liver disease. If you have a pre-existing liver disease, inform your doctor before receiving this medication. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.
While specific precautions for kidney impairment are not extensively detailed, informing your doctor about any kidney-related issues is crucial. This helps assess potential risks and adjust treatment accordingly.
Pegadria is not recommended during pregnancy due to the risk of embryo-fetal toxicity. It is not recommended to use it while breastfeeding. It may pass through the milk and affect the infant. If breastfeeding, inform your doctor, who may advise stopping breastfeeding during treatment.
Avoid this injection if you are allergic to Doxorubicin or any other components of this medicine. Avoid consuming alcohol during treatment, as it may increase the risk of side effects. Furthermore, avoid self-administering this injection.
FAQs
What is the Pegadria 20 mg injection used for?
Pegadria is an Anticancer medication used to treat various Cancers, including Breast Cancer, Neuroblastoma, and Wilms' tumor. It contains Doxorubicin, an Anthracycline Topoisomerase inhibitor, which disrupts DNA synthesis in Cancer cells, preventing their growth. It is administered as adjuvant Chemotherapy and effectively manages metastatic and pediatric Cancers.
How does Pegadria 20 mg injection work in treating Cancer?
Pegadria treats Cancer by targeting the DNA of Cancer cells. Its active ingredient, Doxorubicin, inhibits the Topoisomerase II enzyme by intercalating DNA base pairs, causing the double helix to uncoil. This disruption halts DNA and RNA synthesis, preventing Cancer cells from growing and dividing and ultimately destroying them.
Are there any side effects of using Pegadria 20 mg Injection?
Yes, Pegadria injection can cause several side effects, including nausea, vomiting, hair loss, low blood cell counts, skin rashes, diarrhea, and mouth sores. Serious side effects may include fever, severe diarrhea, lung infections, and severe weakness. It can also cause dizziness, affecting the ability to drive or operate machinery.
Can Pegadria 20 mg Injection be used alongside other Cancer treatments?
Yes, if your doctor prescribes, Pegadria can be used alongside other Cancer treatments. It is often combined with other Anticancer agents to enhance therapeutic efficacy, targeting multiple pathways to combat Cancer more effectively. Such combination therapies can reduce drug resistance, improve tumor control, and achieve better clinical outcomes than single-drug treatments.
How often is Pegadria 20 mg Injection administered during Chemotherapy?
Pegadria is typically administered once every 3 weeks during Chemotherapy cycles. The exact frequency and dosage depend on the type of Cancer being treated, your overall health, and your response to treatment. A doctor will determine the appropriate schedule and administer the injection under medical supervision.
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