Valate Chrono 300 Tablet SR
| Pack Size | Price | Qty | Unit Price |
|---|---|---|---|
| 30 Tablet/s | $18.75 | $0.63 | |
| 60 Tablet/s | $31.08 | $0.52 | |
| 90 Tablet/s | $44.09 | $0.49 |
What is Valate 300 SR tablet
Valate 300 SR is an anticonvulsant medication used to treat Epilepsy, seizure disorders, and Bipolar Disorder in adults and children. Its active ingredients are Sodium Valproate (200mg) and Valproic Acid (87mg) in a sustained-release formulation. Anticonvulsants are a class of medications that treat seizures.
The tablet's sustained-release formulation allows for a gradual release of the medicine, providing consistent blood levels over an extended period. Valate 300 works by increasing the levels of Gamma-Aminobutyric Acid (GABA), a neurotransmitter that inhibits excessive neuronal activity in the brain.
Common side effects of Valate 300 include drowsiness, dizziness, nausea, weight gain, and tremor. Rarely, it may cause some serious side effects such as liver damage, pancreatitis, or blood disorders. Psychotropics India Ltd is a reputable manufacturer of Valate 300 SR.
What are the benefits of Valate 300 SR tablet
Valate 300 SR enhances the inhibitory effects of Gamma-Aminobutyric Acid (GABA) in the brain, preventing excessive neuronal firing that can lead to seizures. It also blocks voltage-dependent sodium and T-type calcium channels, further stabilizing neuronal membranes and preventing the spread of abnormal electrical activity.
Valate 300 offers multiple therapeutic benefits:
- Effective control of various seizure types, including absence, myoclonic, and tonic-clonic seizures.
- Management of Bipolar Disorder, particularly in preventing manic episodes.
- The extended-release formulation provides consistent drug levels throughout the day.
- Reduces the frequency of migraine headaches in some patients.
- It may be effective when other anticonvulsants have failed.
It is crucial to note that Valate 300 requires consistent blood level monitoring, especially when initiating therapy or adjusting dosage.
How to take Valate 300 SR tablet
Valate is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:
- Take Valate 300 once or twice daily, depending on your doctor's recommendation.
- Swallow the tablets whole with water; do not crush, chew, or break the tablets.
- Take with food to minimize gastrointestinal side effects.
- Do not exceed the prescribed Valate dosage without consulting your healthcare provider.
Strength and substitutes
The strength and substitutes available for Valate Chrono are:
| $8.80 / 10 tablet |
What are the side effects of Valate 300 SR tablet
Valate is generally effective for seizure control. However, it may cause side effects, including:
- Drowsiness, dizziness, and headache
- Nausea, vomiting, and digestive discomfort
- Weight gain and increased appetite
- Tremor and hair loss
- Menstrual irregularities in women
These adverse effects often diminish as your body adjusts to the medication. However, serious side effects like yellowing of skin/eyes, unusual bleeding/bruising, or severe abdominal pain require immediate medical attention.
Safety Advice
Valate 300 is contraindicated in patients with liver disease or significant liver dysfunction due to the risk of severe hepatotoxicity. Regular liver function tests are mandatory for all patients, especially during the first six months of treatment. Any signs of liver problems warrant immediate medical attention and possible discontinuation of the medication.
Patients with kidney disease may require dosage adjustments as Valproate is primarily excreted through the kidneys. Free Valproate levels should be monitored in patients with renal impairment, and dosage should be reduced accordingly. Regular monitoring of kidney function is recommended throughout treatment.
Valate 300 is contraindicated during pregnancy due to the high birth defect risk and developmental disorders. Women must use effective contraception during treatment. If planning pregnancy, consult your doctor about alternative treatments. Valproate can pass into breast milk in small amounts. However, breastfeeding is generally safe if prescribed while taking Valate 300. However, consult a doctor for safety.
Alcohol should be strictly avoided as it may increase sedation and the risk of liver damage. Aspirin and other NSAIDs should be used cautiously as they may increase free valproate levels. Avoid supplements containing St. John's Wort as they may decrease valproate effectiveness. Carbonated beverages should be limited as they may accelerate tablet dissolution and affect sustained release properties.
FAQs
Can the use of Valate Chrono 300 Tablet SR cause sleepiness or drowsiness?
Yes, drowsiness is one of the most common side effects of Valate 300 SR, especially when first starting treatment. This effect typically improves over time, but people should avoid driving or operating machinery until they know how the medicine affects them.
Can I drink alcohol while taking Valate Chrono 300 Tablet SR?
No, alcohol should be strictly avoided while taking Valate 300 SR. Alcohol can increase the sedative effects of the medication and potentially increase the possibility of liver damage and other side effects.
Can Valate Chrono 300 Tablet SR be stopped when epilepsy symptoms are relieved?
No, never stop taking Valate 300 SR suddenly, even if seizures are controlled. Abrupt discontinuation can trigger severe, prolonged seizures (status epilepticus). Withdrawal should always be gradual under medical supervision, typically over several weeks or months.
Will a higher than the recommended dose of Valate Chrono 300 Tablet SR be more effective?
No, taking more than the prescribed dose does not improve effectiveness but significantly increases the risk of serious side effects, including liver damage, blood disorders, and pancreatitis. Always adhere to the dose prescribed by your doctor.
Can Valate Chrono 300 Tablet SR be taken with other medications?
Valate 300 SR can interact with many medications, including other anticonvulsants, antibiotics, antidepressants, and blood thinners. Always inform your doctor about all medicines you take to prevent potentially dangerous interactions or reduced effectiveness.
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