Zoxan 500 Tablet
| Pack Size | Price | Qty | Unit Price |
|---|---|---|---|
| 30 Tablet/s | $48.60 | $1.62 | |
| 60 Tablet/s | $85.80 | $1.43 | |
| 90 Tablet/s | $118.80 | $1.32 |
What is Zoxan 500 Tablet
Zoxan 500 Tablet is a broad-spectrum antibiotic belonging to the fluoroquinolone class. Its active ingredient is Ciprofloxacin 500 mg, an FDA-approved bactericidal antibiotic. FDC Ltd. manufactures Zoxan 500 in a GMP-compliant facility under strict quality standards, ensuring consistent dose accuracy and therapeutic reliability in every tablet.
Ciprofloxacin is a DNA gyrase inhibitor antibiotic. It blocks two bacterial enzymes, DNA gyrase and topoisomerase IV, that are necessary for bacterial DNA replication, repair, and transcription. By inhibiting these enzymes, Ciprofloxacin prevents bacteria from reproducing and causes their death, making Zoxan 500 effective against both gram-positive and gram-negative bacteria.
Zoxan 500 mg tablet uses include treating Urinary Tract Infections (UTIs), respiratory infections, including community-acquired Pneumonia, skin and soft tissue infections, bone and joint infections, prostate infections, infectious diarrhea, and certain Sexually Transmitted Infections (STIs) such as Gonorrhea. It is also used in the treatment of Typhoid fever and as post-exposure prophylaxis for anthrax in certain clinical settings.
The typical Zoxan 500 mg dosage is one tablet taken orally once or twice per day, as prescribed by a physician, depending on the type and severity of the infection. Always complete the prescribed course even if symptoms improve early, to prevent antibiotic resistance. If a dose is missed, take it as soon as remembered unless the next Ciprofloxacin dose is near, in which case the missed dose should be skipped. Double-dosing should always be avoided.
Common Zoxan 500 tablet side effects include nausea, diarrhea, vomiting, abdominal discomfort, and headache. Individuals should get immediate medical help if they experience severe allergic reactions, tendon pain or swelling, muscle weakness, or any neurological symptoms such as confusion, tremors, or mood changes.
Before starting Zoxan 500, inform a doctor about any history of tendon disorders, neurological conditions, cardiovascular disease, Diabetes, kidney impairment, or known allergies to fluoroquinolone antibiotics. Store Zoxan 500 below 25°C in a cool, dry place kept away from sunlight and moisture.
What are the benefits of taking Zoxan 500 Tablet
Zoxan 500 Tablet offers clinically established benefits for the treatment of various bacterial infections. Its active ingredient, Ciprofloxacin, delivers bactericidal action by targeting bacterial DNA replication at its source. Key benefits include:
- Urinary Tract Infection treatment: Ciprofloxacin is a trusted bactericidal antibiotic for UTI treatment, effectively clearing both uncomplicated and more severe Urinary Tract Infections caused by susceptible bacteria, including Escherichia coli.
- Respiratory infection relief: Zoxan 500 treats respiratory tract infections, including community-acquired Pneumonia, worsening acute Bronchitis, and sinus infections caused by susceptible bacteria.
- Skin and soft tissue infection management: It effectively targets bacteria responsible for skin, wound, and soft tissue infections, supporting recovery and preventing infection spread.
- Bone, joint, and prostate infection treatment: Ciprofloxacin has good tissue penetration, making it effective in treating bone and joint infections as well as bacterial Prostatitis. These conditions are often difficult to treat with other antibiotics.
- Broad-spectrum bactericidal action: As a DNA-gyrase inhibitor, Zoxan 500 targets a wide range of gram-positive and gram-negative bacteria, making it effective across multiple infection types with consistent, reliable outcomes.
How to take Zoxan 500 Tablet
Zoxan 500 is a prescription antibiotic and must be taken strictly as directed by a doctor. The following are general usage guidelines:
- Swallow the tablet whole with a full glass of water. Do not crush, break, or chew it.
- Take Zoxan 500 at the same time each day to maintain consistent antibiotic levels in the body.
- It can be taken with or without food. However, taking Ciprofloxacin with food can help reduce stomach discomfort.
- Avoid antacids containing aluminum or magnesium, or supplements containing calcium, iron, or zinc, within 2 hours before or 6 hours after taking Zoxan 500, as these significantly reduce Ciprofloxacin absorption.
- Always complete the full prescribed course of treatment, even if symptoms improve before the course ends.
Strengths and Substitutes
Zoxan 500 Tablet is currently available in a single strength at Cheap Medicine Shop. However, you can consider the following alternatives:
| Cefix 100 mg Tablet | $5.80/10 tablets |
| Mahacef 200 Tablet | $2.60/10 tablets |
| Ceftas 400 Tablet DT | $4.80/10 tablets |
What are the side effects of Zoxan 500 Tablet
Like any antibiotic, Zoxan 500 Tablet can cause some side effects. Most are mild and temporary, subsiding as the body adjusts to the medication. However, consult a doctor if they persist or worsen. Seek immediate medical help if severe side effects occur:
- Nausea
- Diarrhea
- Vomiting
- Abdominal discomfort
- Headache
- Dizziness
- Skin rash or sensitivity to sunlight
Seek immediate medical attention if tendon pain or swelling, muscle weakness, numbness or tingling in the limbs, seizures, hallucinations, mood changes, signs of a severe allergic reaction (such as hives, difficulty breathing, or facial swelling), or symptoms of Clostridioides difficile-associated diarrhea (severe abdominal cramping, persistent watery or bloody stools) are experienced.
Safety Advice
Zoxan 500 Tablet should be used with caution in patients with liver disease. Ciprofloxacin is partially metabolized in the liver, and severe hepatic impairment can alter medication clearance and increase systemic exposure. Inform a doctor of any liver conditions before starting treatment, as dose adjustment or closer monitoring can be required.
Zoxan 500 Tablet requires dose adjustment in patients with significant kidney impairment. Ciprofloxacin is primarily excreted through the kidneys, and reduced kidney function can lead to medication accumulation and an increased risk of side effects. A doctor should assess kidney function before prescribing this antibiotic and adjust the dose accordingly.
Zoxan 500 Tablet is generally not recommended during pregnancy. Animal studies have shown that Ciprofloxacin can affect developing cartilage, and its safety in human pregnancy has not been fully established. It should be used only during pregnancy when a doctor determines that no safer alternative is available and that the benefit clearly outweighs the risk. Ciprofloxacin passes into breast milk, and breastfeeding should be avoided during treatment unless a doctor advises otherwise.
Do not use Zoxan 500 in those with known hypersensitivity to Ciprofloxacin or other fluoroquinolone antibiotics. Avoid use with other QT-prolonging medications, as Ciprofloxacin can prolong the QT interval and increase the risk of serious cardiac arrhythmias (irregular heartbeats). Do not use alongside Tizanidine, as this combination can lead to a sudden fall in blood pressure and increased sedation. Avoid sun exposure and tanning beds during Zoxan treatment, as Ciprofloxacin increases photosensitivity. In line with the FDA Black Box Warning, use with caution or avoid in patients over 60, those on corticosteroids, and individuals with a history of tendon disorders, as the risk of Tendinitis and tendon rupture is significantly elevated. Inform a doctor of all current medications, particularly theophylline, warfarin, antacids, and antidiabetic medications, as Ciprofloxacin can interact with these and alter their effects.
FAQs
How should I take Zoxan 500 Tablet?
Take Zoxan 500 whole with a full glass of water at the same time each day, with or without food. Avoid taking it within 2 hours of antacids or supplements containing aluminum, magnesium, calcium, iron, or zinc. Follow the prescribed dose and complete the full course.
Can Zoxan 500 Tablet be taken with antacids?
No, antacids containing aluminum or magnesium should not be taken within 2 hours before or 6 hours after Zoxan 500. They can bind to Ciprofloxacin, reducing its absorption and making the medicine less effective. Consult a doctor about safer timing or alternatives.
Is Zoxan 500 Tablet safe during pregnancy?
No, Zoxan 500 is generally not recommended during pregnancy. It should only be used if a doctor decides it is clearly necessary and no safer antibiotic is suitable, after carefully weighing the potential risks and benefits.
How long does Zoxan 500 Tablet stay active in the body?
Zoxan 500 contains Ciprofloxacin, which has a half-life of about 4 to 6 hours. In adults with normal kidney function, it is mostly cleared within 20 to 30 hours after the last dose. Kidney impairment can make it stay in the body longer.
Can Zoxan 500 Tablet be used for UTI?
Yes, Zoxan 500 can be used for uncomplicated and complicated UTIs caused by susceptible bacteria. It works well because Ciprofloxacin reaches high levels in the urinary tract. However, a doctor should confirm the infection and determine the appropriate antibiotic.
What should I avoid while taking Zoxan 500 Tablet?
Avoid antacids, dairy products, and mineral supplements within 2 hours of Zoxan 500, as they can reduce absorption. Avoid too much sun, tanning beds, alcohol, and driving if dizzy. Also, avoid strenuous activity if tendon pain or stiffness develops, and contact a doctor immediately.
Can I stop taking Zoxan 500 Tablet early if I feel better?
No, do not stop Zoxan 500 early, even if symptoms improve. Stopping an antibiotic too soon may leave some bacteria alive, leading to a return of the infection and increasing the possibility of antibiotic resistance. Complete the full prescribed course unless a doctor tells you to stop.
What is the FDA Black Box Warning for Zoxan 500 Tablet?
The FDA Black Box Warning for Zoxan 500, which contains Ciprofloxacin, highlights serious risks such as peripheral neuropathy, tendon rupture, and Central Nervous System effects like seizures or hallucinations. These effects may be permanent, so it should be used only when safer alternatives are not suitable.
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