What is A-Bec Tablet

A-Bec Tablet is an antiretroviral medication designed specifically to treat Human Immunodeficiency Virus (HIV) infection cases and Acquired Immunodeficiency Syndrome (AIDS) disease management. The active ingredient in this medicine is Abacavir (300 mg), an FDA-approved Nucleoside Reverse Transcriptase Inhibitor (NRTI) that plays a crucial role in controlling HIV viral replication and supporting immune system function.

This HIV infection treatment works by blocking the action of reverse transcriptase, an enzyme that HIV uses to replicate and multiply within the body. By inhibiting viral replication, Abacavir helps reduce the viral load in the blood, allowing the immune system to recover and function better. Emcure Pharmaceuticals, India, manufactures A-Bec Tablet in GMP-compliant facilities under stringent quality control measures.

A-Bec Tablet is always used as part of a combination HIV treatment with other antiretroviral medications, never alone. The typical dosage is one tablet (300 mg) twice daily or as prescribed. Common side effects include nausea, headache, fatigue, loss of appetite, and diarrhea. However, a serious hypersensitivity reaction can occur in some patients, requiring immediate discontinuation of the medication.

Before starting treatment, genetic testing (HLA-B*5701) is recommended to identify patients at risk for hypersensitivity reactions. Patients with liver disease, heart problems, or a history of hepatitis should inform their doctor. Regular monitoring of viral load, CD4 count, and liver function is essential during treatment. Store A-Bec Tablet in a cool, dry place away from direct sunlight and moisture at room temperature below 25°C, keeping it out of reach of children.

What are the benefits of taking A-Bec Tablet

A-Bec Tablet offers significant benefits for individuals living with HIV infection as part of antiretroviral therapy:

• Viral replication inhibition: A-Bec Tablet effectively blocks HIV replication in the body by inhibiting the reverse transcriptase enzyme, reducing viral load in the bloodstream and helping maintain low viral loads.
• Immune system support: By controlling viral replication and reducing HIV viral load, Abacavir allows the immune system to recover and strengthen, improving the body's ability to fight infections and diseases associated with AIDS.
• Long-term HIV management: When used consistently as part of combination therapy, A-Bec helps maintain viral suppression over the long term, improving quality of life and life expectancy for people living with HIV.
• Disease progression prevention: Regular use of A-Bec Tablet as prescribed helps prevent the progression from HIV infection to AIDS by keeping the virus under control and preserving immune function.

How to take A-Bec Tablet

A-Bec Tablet is a prescription medication that should be taken as directed by a healthcare professional. Here are the general guidelines for taking this medication:

• Take A-Bec Tablet exactly as prescribed, typically one 300 mg tablet twice daily as part of combination antiretroviral therapy.
• Swallow the whole tablet with a glass of water without crushing, breaking, or chewing it.
• You can take A-Bec Tablet with or without food, according to your preference and tolerance.
• Take doses at the same times each day to maintain consistent medication levels in your blood. Never exceed the prescribed dosage, skip doses, or stop treatment without consulting your doctor.

Strengths and Substitutes

A-Bec is available only in a single strength for HIV infection treatment. However, you can consider the following substitutes:

View all substitutes

What are the side effects of A-Bec Tablet

Like any medication, A-Bec Tablet may cause mild side effects that generally subside as the body adjusts to the treatment. However, consult a healthcare professional if they persist or worsen:

• Nausea or vomiting
• Headache
• Fatigue or weakness
• Loss of appetite
• Diarrhea
• Fever

Safety Advice

Liver Disease

People with liver disease, including Hepatitis B or C co-infection, should use A-Bec Tablet with caution. Abacavir is metabolized in the liver and can cause hepatotoxicity, especially in those with pre-existing liver conditions. Regular liver function tests are essential, and dosage adjustments may be necessary.

Kidney Impairment

A-Bec Tablet typically does not require dosage adjustment in patients with kidney impairment, as Abacavir is primarily metabolized by the liver rather than excreted by the kidneys. However, inform your healthcare provider about any kidney problems for appropriate monitoring and comprehensive management of your HIV treatment.

Pregnant and Breastfeeding women

Pregnant women with HIV can use A-Bec Tablet under medical guidance to prevent mother-to-child transmission of the virus. However, breastfeeding is not recommended for HIV-positive mothers, as the virus can be transmitted to the baby via breast milk. Discuss treatment options and infant feeding choices with your healthcare provider before and during pregnancy.

Avoid

Avoid alcohol consumption while taking A-Bec Tablet, as it might increase the risk of liver damage and worsen side effects. People who have previously experienced hypersensitivity reactions to Abacavir should never take this medication again, as re-challenge can be fatal. Inform your doctor about all medications you are taking, including other antiretrovirals, to prevent drug interactions. Never share A-Bec tablets with others or skip doses, as this can lead to medication resistance.