What is Augmed 625 mg tablet

Augmed 625 mg is a powerful broad-spectrum antibiotic tablet containing Amoxycillin (500mg) and Clavulanic Acid (125mg). This combination therapy is designed to treat a wide range of bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and dental infections.

Manufactured by GlaxoSmithKline Pharmaceuticals Ltd, this prescription medication works through a dual-action mechanism: Amoxycillin kills bacteria by inhibiting cell wall synthesis, while clavulanic acid protects Amoxycillin from degradation by beta-lactamase enzymes that certain resistant bacteria produce.

Common side effects of Augmed include diarrhea, nausea, vomiting, and skin rash. This medication is generally well-tolerated but requires completing the full prescribed course even if symptoms improve quickly. It is not suitable for patients with a known hypersensitivity to penicillin or those with a history of Augmed-associated liver dysfunction.

What are the benefits of Augmed 625 mg tablet

Augmed 625 operates through a synergistic mechanism combining Amoxycillin, a beta-lactam antibiotic, with Clavulanic Acid, a beta-lactamase inhibitor. Amoxycillin binds to penicillin-binding proteins, inhibiting bacterial cell wall synthesis and causing cell death.

Meanwhile, Clavulanic Acid protects Amoxycillin from destruction by beta-lactamase enzymes produced by resistant bacteria.

This powerful combination extends the antibiotic spectrum to include:

• Beta-lactamase-producing strains of H. influenzae and M. catarrhalis.
• Resistant strains of Staphylococcus aureus.
• Many anaerobic bacteria are resistant to Amoxycillin alone.
• Various gram-negative bacteria, including E. coli and Klebsiella species

It is crucial to note that Augmed must be taken consistently at scheduled intervals to maintain effective blood levels for optimal bacterial eradication.

How to take Augmed 625 mg tablet

Augmed 625 is a prescription medication that should be taken per your doctor's instructions. Here are the general guidelines:

• Take Augmed 625 every 12 hours (twice daily) with meals.
• Swallow tablets whole with a full glass of water; do not crush or chew.
• Take with food at evenly spaced intervals to maintain consistent antibiotic blood levels.
• Complete the full course your doctor prescribes, even if you feel better before finishing.

Strength and substitutes

The strength and substitutes available for Augmed are:

View all substitutes

What are the side effects of Augmed 625 mg tablet

Augmed is generally well-tolerated but may cause side effects, including:

• Diarrhea or loose stools (most common)
• Nausea and vomiting
• Skin rash or itching
• Oral or vaginal candidiasis (thrush)
• Elevated liver enzymes (rare)

These adverse effects typically do not require medical consultation unless severe or persistent. Mild digestive symptoms often resolve during treatment as your body adjusts to the medication.

Safety Advice

Liver disease

Use Augmed 625 with caution if you have liver disease. Dose adjustment or alternative antibiotics may be necessary for patients with severe Hepatic impairment. Regular liver function monitoring is recommended, as rarely, Augmed can cause Hepatitis or Cholestatic Jaundice. Discontinue immediately if signs of liver dysfunction develop.

Kidney impairment

Patients with kidney impairment require dose adjustment based on creatinine clearance. For moderate renal impairment (GFR 10-30 mL/min), the dosing interval should be extended to every 12 hours with a reduced dosage. Severe renal impairment (GFR <10 mL/min) may require further reductions or alternative antibiotics. Regular monitoring of kidney function is recommended.

Pregnant and breastfeeding women

Augmed is generally considered safe during pregnancy (Category B) with no evidence of increased birth defects. It should be used only when needed and when potential benefits outweigh the risks. The medicine can pass into breast milk in small amounts but is generally considered compatible with breastfeeding. Monitor breastfed infants for diarrhea, candidiasis, or allergic reactions.

Avoid

Avoid alcohol during antibiotic treatment as it may increase the risk of liver-related side effects and stomach irritation. Do not take Augmed with medications containing probenecid, as this can increase Amoxicillin levels. Allopurinol taken concurrently may increase the risk of skin rashes.