Augmed 375 Mg Tablet

What is Augmed 375 mg tablet

Augmed 375 mg is an effective combination antibiotic tablet containing Amoxycillin and Clavulanic Acid that treats various bacterial infections. This formulation suits mild to moderate infections and pediatric patients requiring lower antibiotic doses.

Manufactured by GlaxoSmithKline Pharmaceuticals Ltd, Augmed 375 mg works through a complementary mechanism: Amoxycillin directly attacks bacterial cell walls, while clavulanic acid neutralizes resistance enzymes. It is commonly prescribed for sinusitis, bronchitis, ear infections, urinary tract infections, and mild skin infections.

Side effects may include mild digestive disturbances, headaches, and occasional allergic reactions. This medication begins working within hours of administration but requires the complete prescribed course to prevent bacterial resistance. Augmed 375 is contraindicated in patients with Penicillin allergy, Mononucleosis, or a history of Augmed-related jaundice.

What are the benefits of Augmed 375 mg tablet

Augmed 375 mg functions through a sophisticated dual-action mechanism where Amoxycillin, a semisynthetic penicillin, disrupts bacterial cell wall synthesis by binding to specific penicillin-binding proteins. Simultaneously, Clavulanic Acid inactivates bacterial beta-lactamase enzymes that would otherwise break down Amoxycillin before it can work.

This strategic combination is particularly valuable for treating:

• Community-acquired respiratory tract infections
• Recurrent Tonsillitis and Sinusitis
• Uncomplicated Urinary Tract Infections (UTIs)
• Infected animal or human bites
• Early-stage cellulitis and soft tissue infections

It is crucial to note that Augmed offers an optimal balance of effectiveness and tolerability for patients requiring lower antibiotic doses, including elderly patients with compromised renal function and pediatric cases.

How to take Augmed 375 mg tablet

Augmed 375 is a prescription medication that should be taken per your doctor's instructions. Here are the general guidelines:

• Take Augmed every 8 hours (3 times daily) with food.
• Always take it at the start of a meal to reduce stomach upset.
• Maintain adequate hydration (at least 8 glasses of water daily) while on this medication.
• Take it with food and do not exceed the prescribed Augmed dose or treatment duration.

Strength and substitutes

The strength and substitutes available for Augmed are:

View all substitutes

What are the side effects of Augmed 375 mg tablet

Augmed 375 is generally well-tolerated when taken as directed. However, it may cause side effects, including:

• Mild to moderate diarrhea
• Stomach discomfort or indigestion
• Headache
• Oral or vaginal yeast infections
• Skin rash (may indicate allergy)

These adverse effects typically resolve without medical intervention as treatment progresses. However, severe diarrhea, jaundice, or persistent fever warrants immediate medical attention.

Safety Advice

Liver disease

Patients with liver impairment should use Augmed 375 cautiously. Liver function tests should be monitored before and during treatment. Those with previous jaundice/hepatic dysfunction related to amoxicillin-clavulanate should avoid this medication entirely. No dosage adjustment is typically necessary for mild hepatic impairment, but treatment duration should be limited when possible.

Kidney impairment

Dosage adjustment is necessary for patients with kidney impairment based on creatinine clearance values. For moderate impairment, the standard dose can be given every 12 hours instead of every 8 hours. In severe renal impairment (GFR <10 mL/min), Augmed 375 is generally not recommended, and alternative antibiotics should be considered after consultation with a specialist.

Pregnant and breastfeeding women

Augmed 375 falls under Pregnancy Category B, indicating no evidence of risk in humans. It should be used during pregnancy only when needed, and the benefits outweigh the potential risks. Small amounts are excreted in breast milk but are considered safe for nursing infants. However, monitor breastfed infants for potential sensitization, diarrhea, or yeast infections. Consult your healthcare provider before use.

Avoid

Avoid Augmed with fruit juices or alcohol, as these may reduce its effectiveness and increase gastrointestinal side effects. Taking Augmed with Methotrexate may increase its levels, potentially leading to toxicity. Certain probiotic supplements should be taken at least 2 hours before or after this antibiotic to maintain the effectiveness of both treatments.