What is Nepablu 5

Nepablu 5 ml is designed specifically for the management of postoperative eye inflammation and ocular pain relief following cataract surgery and other ophthalmic procedures. The active ingredient is Nepafenac (0.1% w/v), an FDA-approved Nonsteroidal Anti-inflammatory drug (NSAID) that provides effective prostaglandin inhibition in ocular tissues. Lupin, India, manufactures Nepablu 5 ml in GMP-compliant facilities.

This ophthalmic NSAID eye drops solution works by inhibiting Cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2, which catalyze prostaglandin synthesis. Prostaglandins are inflammatory mediators that cause eye swelling, redness, pain, and discomfort following surgical procedures.

By blocking prostaglandin production, Nepafenac effectively reduces inflammation, controls eye swelling, and provides significant relief of ocular pain. Nepafenac is a prodrug that penetrates the cornea effectively and is converted to its active form, Amfenac, within ocular tissues, providing superior anti-inflammatory efficacy. It also minimizes redness, eye watering, and itching.

The typical Nepafenac dosage is 1 drop in the affected eye 3 times daily, beginning 1 day before cataract surgery, continuing on the day of surgery, and for 2 weeks post-surgery, or as prescribed by your ophthalmologist. Common side effects include temporary eye discomfort, foreign body sensation, increased tearing, mild blurred vision, and eye redness, which usually resolve quickly.

Before using Nepablu, inform your doctor about any bleeding disorders, Aspirin sensitivity, or other eye conditions. Patients with known hypersensitivity to NSAIDs or Aspirin should use this medication with caution. Contact lens users should remove lenses before application and wait at least 10 minutes before reinserting them.

Store Nepablu 5 ml eye drops at room temperature below 30°C. Protect it from light, and keep the bottle tightly closed. Once opened, use within 4 weeks and keep out of reach of children.

What are the benefits of using Nepablu 5

Nepablu offers important therapeutic benefits for patients undergoing eye surgery and requiring surgical eye care, such as:

• Postoperative inflammation control: Nepablu effectively reduces eye swelling, redness, and inflammation following cataract surgery and other ocular procedures by inhibiting prostaglandin synthesis. This action promotes faster healing and improved visual recovery outcomes.
• Ocular pain management: These NSAID eye drops provide significant relief from postoperative eye pain and discomfort, like watering eyes. It reduces the need for systemic pain medications and improves patient comfort during the critical healing period after surgical eye care procedures.
• Macular Edema prevention: Nepafenac helps prevent Cystoid Macular Edema (CME), a potentially vision-threatening complication that can occur after cataract surgery, by controlling inflammatory responses in the retina and maintaining optimal visual acuity.

How to use Nepablu 5

Nepablu 5 ml is a prescription eye drop medication that should be used as directed by a healthcare professional. Here are the general guidelines:

• Instill one drop of Nepablu in the affected eye 3 times daily as prescribed by your ophthalmologist.
• Wash your hands thoroughly, tilt your head back, pull the lower eyelid, and apply the drop without touching the dropper tip to your eye.
• Usually, the treatment begins one day before scheduled cataract surgery, continues on the surgery day, and lasts for the prescribed postoperative period, typically 2 weeks.
• If using multiple eye drops, wait at least 5 minutes between different medications, and remove contact lenses before application.

Strengths and Substitutes

Nepablu is currently available only in a single-strength formulation at Cheap Medicine Shop. However, you can try these effective alternatives for ophthalmic NSAID therapy:

View all substitutes

What are the side effects of Nepablu 5

Like any medication, Nepablu 5 ml may cause some side effects. Most side effects are mild and temporary, resolving as your eye heals from surgery. However, consult a healthcare professional if they persist or worsen:

• Eye discomfort
• Irritation
• Foreign body sensation
• Increased tearing
• Blurred vision
• Eye redness

Safety Advice

Liver Disease

Patients with liver disease can generally use Nepablu safely, as topical ophthalmic NSAID therapy results in minimal systemic absorption. However, inform your healthcare provider about any liver conditions. While systemic effects are rare with eye drops, people with severe impairment should be monitored during extended use.

Kidney Impairment

Nepablu can be used in patients with kidney impairment without specific dosage adjustments, as the medication is applied topically to the eye with minimal systemic absorption. However, inform your ophthalmologist about any kidney problems, especially if using the medication for extended periods beyond the typical postoperative treatment duration.

Pregnant and Breastfeeding women

Pregnant and breastfeeding women should use Nepablu only under strict medical supervision and when clearly necessary. NSAIDs may pose risks during the third trimester of pregnancy. While systemic absorption from eye drops is minimal, discuss with an ophthalmologist before using this medication during pregnancy or while breastfeeding.

Avoid

Avoid touching the dropper tip to your eye to prevent contamination and potential eye infections. Patients with known hypersensitivity to Nepafenac or other NSAIDs should not use this medication due to the risk of severe allergic reactions. Do not wear contact lenses during active eye inflammation or for at least 10 minutes after applying the drops.