Pruwel 2 Tablet
| Pack Size | Price | Qty | Unit Price |
|---|---|---|---|
| 30 Tablet/s | $54.45 | $1.82 | |
| 60 Tablet/s | $103.45 | $1.72 | |
| 90 Tablet/s | $145.38 | $1.62 |
What is Pruwel 2
Pruwel 2 tablet, containing the active salt Prucalopride (2 mg), is a specialist therapy for persistent idiopathic constipation in adults. This is particularly useful when laxatives (substances that promote bowel movement) are unsuccessful. Intas Pharmaceuticals Ltd. manufactures this prescription medication in a GMP-compliant facility.
Prucalopride is an FDA-approved selective 5-hydroxytryptamine type 4 (5-HT4) receptor agonist, also known as a prokinetic laxative, that specifically activates 5-HT4 serotonin receptors in the intestinal lining, promoting regular bowel movements. The prescribed dosage is one pill daily, which can be adjusted according to age or severity of the condition.
If you missed a dosage, have it as soon as you recall. But if it is close to the next dose, avoid taking it to compensate for the missed one. An overdose can cause severe diarrhea or headaches. In such a case, get emergency treatment right away.
Potential side effects include headache, nausea, stomach discomfort, diarrhea, and dizziness. Consult a doctor immediately if you experience chronic vomiting, allergic reactions, or an abnormal heartbeat. Avoid the medication if you have intestinal blockage or are taking other 5-HT4 agonists to avoid potential interactions or reduce the likelihood of side effects.
Pruwel tablet should be stored in a cool, dry location (below 30°C), away from direct light and moisture.
What are the benefits of taking Pruwel 2
Prucalopride, in this chronic constipation treatment, specifically activates 5-HT4 serotonin receptors in the gut's smooth muscle and neurons. This facilitates acetylcholine release, a key neurotransmitter responsible for stimulating coordinated intestinal contractions.
Prucalopride promotes stool movement by strengthening and regulating bowel movement. This produces softer, more predictable bowel motions and promotes regular evacuation of stool without the strong stimulant effect associated with certain laxatives.
Primary applications include:
- Treating long-term constipation
- Decreases the sensation of incomplete stool evacuation
- Relieves abdominal bloating
- Reduces excessive straining
How to take Pruwel 2
For effective use, take the medication as exactly prescribed by your doctor. However, some common usage guidelines are as follows:
- Have this intestinal motility agent at the same time every day to enhance absorption and prevent constipation.
- Consume the entire tablet at once with a sufficient amount of water. Do not chew, break, or crush.
- You can have the pill with or without food.
- The usual prescribed dose is one tablet a day.
Strengths and Substitutes
Currently, we provide this gut motility medicine exclusively in a 2 mg dose. If this does not match your prescribed regimen, contact your doctor to find a suitable replacement. A few commonly sold substitutes are:
| Nexpro 20 mg | $1.40/10 pills |
| Pan 20 mg | $3.00/10 pills |
What are the side effects of Pruwel 2
Although this digestive system medicine is generally well-tolerated, some patients report temporary adverse effects, including:
- Nausea
- Abdominal cramping
- Dizziness
- Fatigue
- Headaches
These symptoms are mild and occur most frequently on the first day of treatment and subside as therapy continues. If you observe any persistent or worsening side effects, contact your medical provider immediately.
Safety Advice
Patients with significant liver dysfunction could have increased levels of this Prucalopride tablet in their blood, as the liver is responsible for the metabolism of the medication. To ensure safety, doctors typically recommend a reduced starting dose of 1 mg once daily for these individuals.
In patients with kidney problems, this Prucalopride 2 mg pill could not be effectively eliminated from the circulation, resulting in toxicity. This can impair kidney function or cause major problems, making it unsuitable for routine usage in such cases.
Due to possible health risks to the fetus and baby, this bowel movement stimulant is usually avoided during pregnancy and breastfeeding. It should only be used if a doctor determines that the benefits clearly exceed the risks.
Alcohol can interfere with how this Serotonin receptor agonist works, making treatment less effective and increasing unwanted side effects like dizziness; hence, it should be avoided.
FAQs
Does Pruwel help with bloating?
Yes, Pruwel can help reduce bloating in patients with chronic constipation. By stimulating 5-HT4 receptors and improving bowel motility, it promotes regular stool passage, relieving stool retention and the associated abdominal discomfort.
Can Pruwel be used for constipation related to Irritable Bowel Syndrome?
Yes, Pruwel can be used for constipation related to Irritable Bowel Syndrome (IBS) in some adults. It improves bowel motility and stool frequency, but a doctor should guide use to ensure safety and monitor symptom response.
How long should Pruwel be consumed?
The duration of Pruwel use depends on the severity of your constipation and your response to treatment. Some patients might need it for several weeks to months under medical supervision, with regular follow-ups to assess effectiveness and adjust the dose if needed.
Can Pruwel be taken at night?
Yes, Pruwel can be taken at night if advised by a doctor; however, it is usually recommended to be taken in the morning to match natural bowel activity. Taking it at a consistent time daily helps improve effectiveness and regular bowel movements.
Does Pruwel soften stools?
No, Pruwel does not directly act as a stool softener. Instead, it improves bowel movements by enhancing intestinal motility, which helps stools pass more easily and regularly, thereby indirectly reducing the hardness and discomfort associated with chronic constipation.
Does Pruwel work for occasional constipation?
No, Pruwel is primarily intended for chronic constipation, not for occasional constipation. Occasional constipation is usually managed effectively with dietary fiber, fluids, lifestyle changes, or short-term laxatives, rather than long-term motility-enhancing medications like Pruwel.
Can Pruwel be stopped suddenly?
Yes, Pruwel can be stopped suddenly without gradually reducing the dose, as it is not habit-forming. However, constipation symptoms return progressively after stopping the medicine, so it is advisable to consult a doctor before discontinuing long-term treatment.
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