Ramloz H 2.5 Mg/12.5 mg Tablet
| Pack Size | Price | Qty | Unit Price |
|---|---|---|---|
| 150 Tablet/s | $23.42 | $0.16 | |
| 300 Tablet/s | $42.00 | $0.14 | |
| 450 Tablet/s | $56.70 | $0.13 |
What is Ramloz H 2.5 Mg/12.5 mg tablet
Ramloz H 2.5 mg/12.5 mg is a fixed-dose combination antihypertensive medication containing Ramipril (2.5mg) and Hydrochlorothiazide (12.5mg). Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that dilates blood vessels, while Hydrochlorothiazide is a thiazide diuretic that removes excess fluid from the body.
Shreya Life Sciences Pvt Ltd, a reputable pharmaceutical company, manufactures this effective combination therapy. This medicine is primarily prescribed for those with essential Hypertension whose blood pressure remains inadequately controlled on monotherapy.
The combination provides comprehensive blood pressure management through complementary mechanisms of action. It is not recommended as initial therapy but is valuable for patients requiring multiple agents for optimal control.
Side effects of these tablets may include dry cough, dizziness, headache, increased urination, and electrolyte imbalances. Store Ramloz H in a cool, dry place below 30°C, away from direct sunlight and moisture. Patients with a history of Angioedema, kidney disorders, or electrolyte disturbances should use it with caution.
This medication is contraindicated during pregnancy, especially in the second and third trimesters.
What are the benefits of Ramloz H 2.5 Mg/12.5 mg tablet
Ramloz H works through a synergistic dual mechanism to effectively control Hypertension. Ramipril blocks the angiotensin-converting enzyme, inhibiting the formation of angiotensin II and resulting in vasodilation and reduced aldosterone secretion.
Concurrently, Hydrochlorothiazide increases sodium and water excretion by the kidneys, decreasing blood volume and vascular resistance.
The combination offers significant advantages over monotherapy:
- Enhanced antihypertensive efficacy through complementary mechanisms.
- Better 24-hour blood pressure control with once-daily dosing.
- Counteraction of compensatory mechanisms that limit single-agent effectiveness.
- Potential for reduced dose-dependent side effects compared to higher doses of individual components.
- Additional benefits in specific populations such as diabetic patients and those with heart failure.
Regularly monitoring electrolyte levels, blood pressure, and kidney function is essential during treatment with Ramloz H to ensure optimal therapeutic outcomes and minimize adverse effects.
How to take Ramloz H 2.5 mg/12.5 mg tablet
Ramloz H 2.5 mg/12.5 mg is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:
- Take 1 Ramloz H tablet daily, preferably in the morning.
- Swallow the tablet with a glass of water. Do not crush or break the tablet.
- It can be taken with or without food, but consistent timing improves effectiveness.
- Do not exceed the prescribed dosage of this medication.
Strengths and substitutes
The following are the substitutes for the Ramloz-H tablet, available at the Cheap Medicine Shop.
| $1.90 / 10 tablets | |
| $2.00 / 10 tablets |
What are the side effects of Ramloz H 2.5 mg/12.5 mg tablet
Ramloz H 2.5 mg/12.5 mg is generally well-tolerated when taken as prescribed. However, it may cause side effects, including:
- Persistent dry cough (primarily from the Ramipril component)
- Increased urination and thirst (due to the Hydrochlorothiazide component)
- Dizziness, especially when standing up quickly
- Fatigue or weakness
- Electrolyte imbalances (particularly low potassium levels)
These effects often resolve as your body adjusts to the medication. However, contact your doctor immediately if you experience severe allergic reactions, swelling of the face/tongue/throat, difficulty breathing, or intense stomach pain.
Safety Advice
Patients with liver impairment should use Ramloz H with caution. The medication may require dosage adjustment as liver dysfunction can alter drug metabolism. Regular monitoring of liver function is recommended. In severe liver disease, the benefits of therapy should be carefully weighed against potential risks.
Close monitoring is essential for patients with kidney disorders. Start with lower doses in moderate impairment, with careful titration based on response. Ramloz H may be ineffective or potentially harmful in severe kidney disease (creatinine clearance <30 ml/min). Regular assessment of kidney function and electrolytes guides appropriate use.
Ramloz H is strictly contraindicated during pregnancy. The ACE inhibitor component can cause injury and death to the developing fetus, mainly in the second and third trimesters. Women should use effective contraception. The medication should also be avoided during breastfeeding as both components may pass into breast milk.
Avoid alcohol consumption while taking Ramloz H as it may enhance the blood pressure-lowering effect and increase the risk of dehydration. Limit grapefruit juice, which can interfere with medication metabolism. Use caution with NSAIDs like ibuprofen, which may reduce the effectiveness of Ramloz H and increase the risk of kidney problems.
FAQs
How should Ramloz H 2.5 mg/12.5 mg tablet be taken for best results?
Take Ramloz H consistently each morning with or without food. Morning administration aligns with your body's natural blood pressure cycle and prevents nighttime urination from the diuretic component. Maintain regular timing and combine it with lifestyle measures like reduced salt intake for optimal results.
How does the diuretic component in Ramloz H 2.5 mg/12.5 mg tablet help reduce blood pressure?
The hydrochlorothiazide component works by increasing sodium and chloride excretion in the kidneys. This promotes water elimination, reducing blood volume and cardiac output. Additionally, it causes mild vasodilation through various mechanisms, which complements the ACE inhibitor's action for enhanced blood pressure reduction.
Will Ramloz H affect my blood sugar levels?
Hydrochlorothiazide in Ramloz H may slightly increase blood glucose levels, particularly in diabetic patients or those with prediabetes. Regular monitoring is advised if you have diabetes. Report any significant changes in blood sugar levels to your healthcare provider for possible dosage adjustments.
How long will I need to take Ramloz H for Hypertension?
Hypertension typically requires long-term management. Many patients need to continue medication indefinitely to maintain healthy blood pressure levels. Never stop taking Ramloz H without consulting your doctor, even if your blood pressure readings improve or normalize with treatment.
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