Ramipres-H Tablet

What is Ramipres-H tablet

Ramipres-H tablet is a combination antihypertensive medication containing Ramipril (2.5mg) and Hydrochlorothiazide (12.5mg). Ramipril belongs to the Angiotensin-converting Enzyme (ACE) inhibitor class, while Hydrochlorothiazide is a thiazide diuretic.

Cipla Ltd, a leading pharmaceutical company renowned for quality medications, manufactures this dual-action formulation. This combination therapy is primarily indicated for the management of essential hypertension in patients whose blood pressure is not adequately controlled with monotherapy.

The synergistic action of both components provides superior blood pressure control compared to either component alone. Ramipres-H is not recommended as initial therapy but is ideal for patients requiring multiple antihypertensive agents.

Common side effects include dry cough, dizziness, fatigue, electrolyte imbalances, and increased urination. Store tablets in a cool, dry place below 30°C, protected from light. Patients with severe kidney or liver impairment, a history of Angioedema, or electrolyte disturbances should use it with caution.

Ramipres-H is contraindicated during pregnancy and requires careful monitoring in elderly patients.

What are the benefits of Ramipres-H tablet

Ramipres-H tablet delivers comprehensive blood pressure control through complementary mechanisms. Ramipril inhibits the Angiotensin-converting Enzyme, preventing the formation of angiotensin II, a potent vasoconstrictor. This results in blood vessel relaxation.

Simultaneously, Hydrochlorothiazide promotes sodium and water excretion through the kidneys, reducing blood volume and lowering blood pressure.

This dual-mechanism approach offers several clinical advantages:

• More effective blood pressure reduction than either component alone.
• Lower doses of each component, potentially reducing side effects.
• Enhanced efficacy in diverse patient populations, including those resistant to monotherapy.
• Complementary actions that counter the compensatory mechanisms that might limit the effectiveness of single agents.
• Kidney-protective effects for those with diabetes while optimizing fluid balance.

Monitoring electrolytes and kidney function is necessary during treatment with Ramipres-H, particularly during the initial weeks of therapy.

How to take Ramipres-H tablet

Ramipres-H is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:

• Take a tablet daily, preferably in the morning.
• Swallow the tablet whole with a glass of water.
• It may be taken with or without food, but consistent timing is recommended.
• Do not exceed the prescribed Rampires H dosage without medical advice.

Strengths and substitutes

The following are the substitutes for Ramipres-H, available at the Cheap Medicine Shop.

View all substitutes

What are the side effects of Ramipres-H tablet

Ramipres-H is generally well-tolerated when used as prescribed. However, it may cause side effects, including:

• Persistent dry cough (from Ramipril component)
• Increased urination (from Hydrochlorothiazide component)
• Dizziness or lightheadedness, especially when standing quickly
• Electrolyte imbalances, particularly low potassium or sodium
• Increased sensitivity to sunlight

These adverse effects typically diminish as your body adjusts to the medication. However, seek immediate medical attention if you experience severe allergic reactions, significant swelling of the face/lips/tongue, yellowing of skin/eyes, or unusual muscle weakness.

Safety Advice

Liver disease

Patients with liver impairment should use Ramipres-H with caution. Reduced liver function may alter drug metabolism, potentially increasing drug levels. Regular liver function monitoring is recommended. In severe liver disease, dosage adjustment may be necessary, or alternative antihypertensive therapy might be considered.

Kidney impairment

Careful monitoring is essential for patients with kidney impairment. Hydrochlorothiazide may be less effective and potentially worsen kidney function in severe cases. Ramipril dosage should be reduced for moderate to severe kidney impairment. Regular assessment of kidney function, electrolytes, and blood pressure response guides appropriate dosage adjustments.

Pregnant and breastfeeding women

Ramipres-H is contraindicated during pregnancy, especially in the second and third trimesters. The ACE inhibitor component can cause fetal injury and death. Women who become pregnant while taking Ramipres-H should discontinue it immediately and consult their doctor. Limited data suggests small amounts may pass into breast milk, so alternative treatments are preferred during breastfeeding

Avoid

Avoid excessive exposure to sunlight while taking Ramipres-H as Hydrochlorothiazide may increase sensitivity to UV radiation. Limit alcohol as it can enhance blood pressure-lowering effects and worsen dizziness. Avoid potassium supplements unless prescribed by your doctor, and use salt substitutes with caution as they may interact with the medication.