US Toll Free Call/Text:
+1(888) 866-7566
Int. No Call/Text:
+1(718) 301-8411

Is It Effective to Take Paroxetine For Premature Ejaculation

Photo of author

Premature Ejaculation (PE) can cause men or Assigned Males at Birth (AMAB) to ejaculate very early.

However, PE is a treatable sexual condition. It can be treated effectively with the help of medicines such as antidepressants. 

Antidepressants such as Dapoxetine and Sertraline can help treat PE. 

A side effect of antidepressants is delaying ejaculation, which is why they are used to treat PE.

Paroxetine is also an antidepressant. So can you take Paroxetine as well for treating Premature Ejaculation? And is it safe to take Paroxetine for Premature Ejaculation?

Yes, you may take Paroxetine for Premature Ejaculation. It is safe and effective in treating PE.

Let us proceed in the article for more information about Paroxetine for treating PE.

Can you take Paroxetine for Premature Ejaculation

Yes, you may take Paroxetine to treat Premature Ejaculation effectively.

Paroxetine is an antidepressant. It belongs to a class of medicine called Selective Serotonin Reuptake Inhibitors (SSRI).

It is an FDA-approved medicine for treating Depression, OCD, Anxiety, and PTSD. 

FDA has not approved Paroxetine for PE. However, doctors often prescribe it off-label due to its effectiveness in treating PE.

Paroxetine increases the level of Serotonin in the body, which helps delay ejaculation.

According to a study on nearly 100 men, Paroxetine was able to treat PE by delaying ejaculation.

A systematic review stated Paroxetine is more effective than other SSRIs and PDE-5 inhibitors in treating PE.

According to, the 15 and 20 mg dosages of Paroxetine may help with PE.

It is advised to consult a doctor before consuming Paroxetine for Premature Ejaculation.

Off-label: A medicine is called off-label when it is prescribed for a health condition it is not approved to treat.

What are the effects of taking Paroxetine for Premature Ejaculation

If you are taking Paroxetine to treat PE, it is important to know about its side effects and interactions.

Paroxetine might cause nausea and weakness.

According to WebMD, here are some of the common and rare side effects of Paroxetine for PE.

Common side effects of ParoxetineRare side effects of Paroxetine
Trouble sleeping 
Loss of appetite
Dry mouth
Blurred vision
Shaking (tremor)
Decreased interest in sex
Changes in sexual ability 
Fast/irregular heartbeat
Eye pain/swelling
Widened pupils
Vision changes
Serotonin Syndrome

Paroxetine can also interact with other medicines and health conditions. It is important to look out for the interactions of Paroxetine as well.

Paroxetine can interact with the following medicines-

  • Amoxapine
  • Acetylcarbromal
  • Bupropion
  • Darunavir
  • Fluoxetine
  • Melatonin
  • Sertraline
Taking oral medication Source: pixelshot
Taking oral medication

 Paroxetine can also interact with the following health conditions-

  • Bone fractures
  • Renal dysfunction
  • Glaucoma
  • Liver disease
  • Platelet function
  • Seizure disorders
  • Weight loss

If you are experiencing any side effects of Paroxetine, seek a doctor immediately. They may give you an alternative medicine like Dapoxetine for treating your PE.

Place your order now:
End Premature Ejaculation Now – Take Control of Your Pleasure! Buy Dapoxetine only from CheapMedicineShop:

  • Duratia 30 mg
  • Poxet 60 mg
  • Alternatives of Paroxetine for Premature Ejaculation

    Although Paroxetine is quite effective in treating PE. However, due to its side effects and interactions, it might not be effective for some people. 

    If you are unable to see any desirable improvements in your PE, consider consulting your doctor. They may prescribe other antidepressants for treating PE effectively.

    According to Mayo Clinic, the following medicines might be taken as an alternative to Paroxetine for PE.

    Alternatives of Paroxetine for PEMedicine Name
    AntidepressantsAntidepressants such as Dapoxetine, Sertraline, and Escitalopram can be taken as an alternative to Paroxetine.
    Studies have mentioned that Dapoxetine is an effective treatment for PE.
    Pain RelieversDoctors might prescribe pain relievers such as Tramadol for treating PE if SSRIs are not effective for PE.
    One of the side effects of Tramadol is Delayed Ejaculation, which is why it may help treat PE. Studies have shown the effectiveness of Tramadol in treating PE. 
    PDE-5  inhibitorsPDE-5 inhibitors or ED medicines such as Viagra and Cialis might help in treating PE.
    Combining ED meds and SSRIs might be more effective for treating PE.

    Besides oral medicines, exercises, supplements, and food might help treat PE.

    Behavioral techniques such as the stop-start strategy may also help in delaying ejaculation.

    Are you seeking a natural alternative to Paroxetine due to its side effects and interactions?

    Supplements are effective alternatives to Paroxetine. To know more about the supplements, read Supplements to Delay Ejaculation: Do They Even Work?

    Key Takeaways

    Premature Ejaculation is a common health condition in men or AMAB. It can cause stress in a relationship. 

    However, it is treatable. Doctors may prescribe antidepressants such as Paroxetine for Premature Ejaculation.   

    Paroxetine is an SSRI that can help in managing the symptoms of PE effectively. 

    It is important to know about the side effects of Paroxetine before taking it for treating PE.

    Some of the side effects of Paroxetine are nausea, drowsiness, and Serotonin Syndrome. It can also interact with the health conditions such as Glaucoma and weight loss.

    If Paroxetine is affecting your health due to its side effects, your doctor may prescribe other medicines, such as Dapoxetine, Tramadol, and Viagra, to treat PE.

    Dapoxetine is specially formulated to treat Premature Ejaculation safely and effectively. 

    If you are experiencing PE symptoms, it is advised to visit a doctor as soon as possible.

    Quick Checkout:
    Premature Ejaculation can affect your relationship. Treat it before it gets out of your hand. Buy medicines for the treatment of PE only from CheapMedicineShop:

  • Poxet 30 mg
  • Vriligy 60 mg
  • Duratia 90 mg
  • Frequently Asked Questions

    Does Paroxetine interact with alcohol and food?

    Yes, Paroxetine can interact with food and alcohol. It can increase the side effects of Paroxetine, such as dizziness and drowsiness. Consult a doctor for more information on the interactions of Paroxetine. 

    Can you take Paroxetine with Cialis?

    Yes, you may take Paroxetine with Cialis. According to, Paroxetine does not interact with Cialis (Tadalafil). However, you should seek medical help before taking Cialis with Paroxetine.

    What are some severe side effects of Paroxetine to look out for?

    Chills, cold sweats, muscle pain, and dry mouth are some severe side effects of Paroxetine. Contact medical help immediately if you experience any side effects.

    How long does Paroxetine take to show its effects on PE?

    Paroxetine usually takes 3-4 hours to show its effects for increasing ejaculation time.

    What will happen if I take more Paroxetine than recommended?

    You may experience symptoms such as nausea, vomiting, and dry mouth if you take more Paroxetine than prescribed. Call a doctor immediately if you witness these symptoms. 

    Cheap Medicine Shop only refers to credible, authoritative sources for our content. If you’re curious about how we ensure the integrity of our content, we encourage you to read our Content Information Policy.

    How useful was this post?

    Click on a star to rate it!

    Average rating 4 / 5. Vote count: 214

    No votes so far! Be the first to rate this post.

    Photo of author Janet Fudge
    Jim Carson is a highly skilled and dedicated medical writer passionate about advancing medical practice. With years of experience in the field of medical sciences, Jim has made significant contributions to various studies aimed at improving healthcare outcomes. He currently writes for, providing expert insights and knowledge on various topics. Jim's expertise extends to various areas, including drug interactions, dosages, side effects, and best practices for medication use. In Los Angeles, Jim lives with his loving wife, children, and beloved pets. He deeply values spending time with his family and cherishes their presence. When he's not writing, Jim enjoys watching football games and staying updated with the latest sports news. Jim's writing shines through his commitment to advancing medical practice and improving healthcare outcomes. Readers can trust Jim's articles to be informative, accurate, and reliable, making him a trusted pharmaceutical information source for the website's audience.
    Please enable JavaScript in your browser to complete this form.

    We’d Love To help

    Reach out to us we will get back to you

    Preferable Time