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Taking Tadalafil and Alcohol Together? Know The Risks

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Tadalafil is an FDA-approved medication to treat Erectile Dysfunction in men or Assigned Men at Birth (AMAB).

You need to avoid certain foods and beverages to reduce the risk of medicine’s side effects. 

One such instance is when you take Tadalafil and alcohol together.

Combining Tadalafil with alcohol might be risky and cause some negative effects.  

Read the article to learn the potential risks of taking Tadalafil and alcohol together. 

We shall also discuss a few measures to reduce the possibility of these risks.

Effects of taking Tadalafil and Alcohol together

alcohol and tadlafiil togetherSource: Getty_images
Alcohol and medicine

For a long time, alcohol has been considered harmful to health. 

According to an NIAAA study, the risk of alcohol interacting with medicines and other substances is common.

One such interaction is with Tadalafil, a Phosphodiesterase type 5 (PDE5) inhibitor

Let’s discuss if you can drink alcohol while taking Tadalafil, its interactions, and possible side effects.

Eager to understand the sexual effects of alcohol on men? Gain insights by reading this articleExploring the Impact: How Does Alcohol Affect a Man Sexually

Can you drink alcohol while on Tadalafil?

Yes, you can drink alcohol while on Tadalafil after consulting your doctor. 

Drinking alcohol moderately while taking Tadalafil might not cause any serious side effects. 

Your doctor may advise limiting your alcohol intake to one or two drinks a day. 

Exceeding the recommended amount of alcohol intake may cause complications.

Curious about the compatibility of generic medicines containing Tadalafil with alcohol? Explore this article to knowCan I Take Tadarise with Alcohol: Know the Risks

Interaction between Tadalafil and alcohol

You may notice a drop in blood pressure after you take Tadalafil. 

Taking alcohol may worsen this effect, which might be risky. 

It may lead to Nausea, headache, dizziness, fatigue, and flushing. 

Excessive blood pressure drops may also cause rare symptoms like heart palpitations.

Your risk of interactions intensifies with increased alcohol consumption.

For an in-depth exploration of interactions of Tadalafil, refer to this articleUnderstanding Tadalafil Interactions

Tadalafil and alcohol side effects

According to, drinking excessive alcohol with Tadalafil is risky and can result in some side effects. 

Your severity of side effects depends on the amount of alcohol you consume. 

Some of the most common side effects of taking Tadalafil and alcohol are:

In rare cases, one may experience heart palpitations.

Heart palpitation is when your heartbeat turns fast, and you may feel a fluttering or pounding heart.

How much alcohol can you drink with Tadalafil?

A study by NCBI states that taking no more than one or two drinks a day with Tadalafil is usually safe. 

However, the exact results depend on one’s immunity and overall health.

Other precautions to take when taking Tadalafil

precautions while taking tadlafil
Suggestion by doctor

As stated earlier, taking moderate amounts of alcohol and Tadalafil together might not be risky. 

To reduce the potential of Tadalafil interactions, you must follow some precautions. 

These may include your Tadalafil dosage, dietary habits, and medicine patterns. 

Here are a few cautions to keep in mind:

  • Limit your alcohol intake. Do not take more than two drinks a day or fifteen drinks a week. 
  • Quit or avoid smoking. Similar to alcohol, Nicotine also alters the way how Tadalafil works. 
  • Do not take grapefruit or grapefruit juice when taking Tadalafil. These food items change the rate of absorption in the body. 
  • Tadalafil is also used to treat Pulmonary Arterial Hypertension (PAH). If you take it for PAH, visit your doctor frequently.
  • Disclose your complete medical history to your doctor before taking Tadalafil. 

Talk to your doctor if your symptoms do not improve, or the condition worsens.


Taking excessive alcohol while taking Tadalafil might be risky. 

It can cause several interactions and side effects.

Depending on your symptom’s severity, these side effects may range from common to rare. 

You should always discuss your alcohol intake with a doctor before taking Tadalafil for ED symptoms

When taking Tadalafil and alcohol, you must exercise caution to reduce side effects.

Frequently Asked Questions

Is it safe to drink alcohol while on Tadalafil?

No. Combining Tadalafil and alcohol might be risky and cause a few side effects. 
Excessive use of alcohol while on Tadalafil may cause fatigue, dizziness, nausea, headache, and flushing. 
Consult your doctor before drinking alcohol if you take Tadalafil or other ED medications.

How many drinks can you have with Tadalafil?

An NCBI study states that taking less than 15 drinks per week with PDE5-inhibitors like Tadalafil is usually safe.  
Taking more than the recommended quantity increases your risk of experiencing side effects.

Why should you not drink alcohol with Tadalafil?

Taking Tadalafil may lower your blood pressure. Mixing it with alcohol intensifies this effect, which might be risky. 
One may experience dizziness, Nausea, fatigue, headache, and even heart palpitations. 
Seek medical advice if you get any of these conditions or your symptoms worsen.

Will alcohol reduce the effectiveness of Tadalafil?

Yes. Alcohol affects the way Tadalafil works.
Taking Tadalafil and alcohol together may cause an excessive drop in blood pressure. 
It may lead to a few side effects, including headache, dizziness, Nausea, and fatigue.

I took Tadalafil and alcohol together. Will I get ill?

Taking alcohol within permissible limits of alcohol might not always be risky. 
However, if you take more than two drinks per day or 15 drinks in a week, you might get a few side effects. 
If your symptoms continue or the condition worsens, consult a physician.

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Photo of author Janet Fudge
Jim Carson is a highly skilled and dedicated medical writer passionate about advancing medical practice. With years of experience in the field of medical sciences, Jim has made significant contributions to various studies aimed at improving healthcare outcomes. He currently writes for, providing expert insights and knowledge on various topics. Jim's expertise extends to various areas, including drug interactions, dosages, side effects, and best practices for medication use. In Los Angeles, Jim lives with his loving wife, children, and beloved pets. He deeply values spending time with his family and cherishes their presence. When he's not writing, Jim enjoys watching football games and staying updated with the latest sports news. Jim's writing shines through his commitment to advancing medical practice and improving healthcare outcomes. Readers can trust Jim's articles to be informative, accurate, and reliable, making him a trusted pharmaceutical information source for the website's audience.
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