Actoforan 500 Mg Injection

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Availability: IN STOCK SKU: CMS4357
Actoforan 500 mg Injection is used in the treatment of non-small cell lung cancer. We provide fast and safe delivery. Buy from our online medicine shop.
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International Brand Name




Generic Name



 Taj Pharma India Ltd

Actoforan 500 Mg Injection (Pemetrexed)

What Is The Generic Name For Actoforan 500 Mg Injection:

Pemetrexed is the generic version for Actoforan 500 mg Injection

Which International Brand is Equivalent To Actoforan 500 Mg Injection (Pemetrexed):


About Actoforan 500 Mg Injection (Pemetrexed)

Actoforan 500 mg Injection contains an active ingredient, Pemetrexed, which is used in the treatment of non-small cell lung cancer & malignant pleural mesothelioma. Non-small-cell lung cancer (NSCLC) is epithelial lung cancer apart from small cell lung carcinoma (SCLC). NSCLCs are relatively not sensitive to chemotherapy as compared to small cell carcinoma. Pleural mesothelioma is a uncommon malignant cancer which is caused by inhaling asbestos fibres into the lungs. Pleural mesothelioma is a type of cancer which develops in the cells that form the outer lining of the lungs & inner lining of the chest cavities. It is the most widespread cancer related to asbestos. This medicine is easily available at all the leading pharmacy, drugstores, & medical supply stores and must be taken strictly on doctor’s prescription only.


Taj Pharma India Ltd. is one of the top pharmaceutical companies which manufacture Actoforan 500 mg Injection.  


Actoforan 500 mg Injection contains an active constituent, Pemetrexed (500 mg). This medicine is easily obtainable in other substitutes also at all the leading online pharmacy, drugstores, & medical supply stores.

What Are The Uses Of The Actoforan 500 Mg Injection (Pemetrexed):

Actoforan 500 mg Injection is used in the treatment in the following conditions:

  • Malignant Pleural Mesothelioma

  • Non-Small Cell Lung Cancer

How Actoforan 500 Mg Injection (Pemetrexed) Works:

Actoforan 500 mg Injection has an active ingredient; Pemetrexed which is an anti-cancer medication. Pemetrexed is an antifolate which contains the pyrrolopyrimidine-based nucleus. Its antineoplastic action is implemented by disrupting folate dependent metabolic processes which is necessary for cell replication. Pemetrexed inhibits folate-dependent enzymes involved in the de novo biosynthesis of thymidine & purine nucleotides. Pemetrexed is transferred into cells by both the reduced folate carrier & membrane folate binding protein transport systems. Once in the cell, pemetrexed is transformed to polyglutamate forms by the enzyme folylpolyglutamate synthetase. The polyglutamate forms are retained in cells & are inhibitors of TS and GARFT. Polyglutamation is a time- & concentration-dependent process which occurs in tumor cells and, to a lesser extent, in normal tissues. Polyglutamated metabolites have an increased intracellular half-life ensuing in prolonged drug action in malignant cells.

Before You Use Actoforan 500 Mg Injection (Pemetrexed):

Make certain that:

  • You are not sensitive to Pemetrexed

  • You are not having any critical Disease

  • Your doctor must be well-informed about your medicinal history like your pre-existing disease, surgeries & Medications, Supplements, Food Habits, lifestyle, etc.

What Should You Avoid While Taking Actoforan 500 Mg Injection (Pemetrexed):

  • You should avoid taking alcohol  

  • You should avoid driving

  • You should avoid taking Medicines without prescriptions

When Not To Use Actoforan 500 Mg Injection (Pemetrexed):

You should not take Actoforan 500 mg Injection if you:

  • Have ever noticed any Allergy/Hypersensitivity

  • Have liver problems

  • Have kidney problems

  • Have skin disorders

  • Have low blood cell count

  • Are pregnant

  • Have infections

  • Are breastfeeding

Tell Your Doctor If You:  

  • Have Allergy to the Injection

  • Are taking Alcohol or Other Drugs

  • Have Liver disease

  • Have infections


Actoforan 500 mg Injection contains an active ingredient, Pemetrexed, which is used in the treatment of non-small cell lung cancer & malignant pleural mesothelioma. This medicine is obtainable in different substitutes & strengths & has got to be purchased or taken on doctor’s prescription only. You must talk about with your physician for adjustment of dosage & time of the medicine since age & severity of the disease differ from person to person, and this can only be finest judged by your doctor.

Adults are advised to take Actoforan 500 mg Injection at a fixed time with or without food as instructed by your Doctor. You must take Actoforan 500 mg Injection regularly on time for better results.

How Much Of The Actoforan 500 Mg Injection (Pemetrexed) to Be Used:

As Actoforan 500 mg Injection is available in various strengths & substitutes, Patients are always advised to follow their doctor’s prescriptions & instructions to take Actoforan 500 mg Injection. You should not take the Injection on your own & for a longer period than recommended by the doctor.

How To Take The Actoforan 500 Mg Injection (Pemetrexed):

Actoforan 500 mg Injection should be taken at a fixed time as directed by your doctor. Your doctor or nurse will give you Actoforan 500 mg Injection. Kindly do not self administer this medicine.

For How Long Should You Continue Using Actoforan 500 Mg Injection (Pemetrexed):

You are always advised to take Actoforan 500 mg Injection as prescribed. Do not start/stop using this medication on your own. You have to strictly follow all the directions given by your doctor. You should not take the Injection in larger or smaller extent or for a longer period than suggested by your doctor.


You have to seek medical emergency treatment and/ or make contact with your medical doctor instantly in case of any overdose symptoms. As Actoforan 500 mg Injection is administered in the hospital or clinical set by an experienced healthcare expert, the likelihood of an overdose is very low. However, emergency action will be initiated without delay by your medical doctor if they detect overdose symptoms.

Missed Dose:

The missed dosage of the Injection ought to be administered as quickly as possible. You should strictly skip the missed dosage if it is by now the time for your next planned dosage. It is advised not to double the dosage of the treatment to make up for the missed dosage. As Actoforan 500 mg Injection is administered in the hospital or clinical set by an experienced healthcare expert, the likelihood of a missed dose is very low.

What Are The Side Effects Of The Actoforan 500 Mg Injection (Pemetrexed):

  • Low WBC and Platelet count

  • Fever and chills

  • Mouth ulcers

  • Nausea and Vomiting

  • Skin rash

  • Decreased urine output

  • Blood in urine and stools

  • Diarrhea

  • Cough

  • Hair loss

  • Change in mood

  • Pharyngitis

  • Loss of appetite

  • Fatigue

  • Anemia (low number of red blood cells)

  • Neuropathy

What Are The Common Drug Interactions:

Some medicines have been reported to interact with Actoforan 500 mg Injection. These interactions might generate some needless or unfavorable effects and/or cause your drug not to operate properly. You must constantly have a discussion with your doctor if you are taking other prescription/ Supplements so that well premeditated medication can be given. It interacts with the following medicines:

  • Clozapine

  • Live attenuated vaccines and related products

  • Fluoroquinolone antibiotic

It can also interact with the following disease condition:

  • Infections

  • Kidney disease

Warning And Precaution:

Actoforan 500 mg Injection can worsen the conditions like:

  • Allergy

  • Kidney/ Liver disease

  • You have to use a consistent contraceptive method to avoid pregnancy while you are on this medication as it can cause birth defects

  • You have to regularly get your blood tests done to examine your blood cells, liver & kidney function, & electrolyte levels during treatment with this medicine

  • You must also get your blood pressure and levels of proteins in urine checked regularly while taking this medicine

  • You should not obtain this medicine if you are pregnant, planning to conceive or breastfeeding

  • You must not drive or operate heavy machines at the same time as taking this medicine as it may cause dizziness

Always talk about with your medical doctor straight away to get the most excellent possible treatment if you are observing several of the above mentioned conditions.

Things To Remember:

  • Keep the Actoforan 500 mg Injection out of reach & sight of the children

  • This medicine is strictly used with vigilance for treatment of children

  • Actoforan 500 mg Injection is not suggested for use in pregnant women owing to the increased risk of harmful effects on the unborn baby

  • You must always check up the information in particular printed on the leaflet/ insert of the medicine

  • Always talk about with your medical doctor if you have any doubt in case of the dosage, time & strength of the medicine.


Actoforan 500 mg Injection should be taken as recommended by your doctor. Do not take this prescription for a longer period than recommended by the medical doctor.


Store the Actoforan 500 mg Injection at room temperature in dark & dry place. Make sure the Injection is intact & not broken while purchasing or storing.


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Item Condition Price Currency MPN Product Id PriceValidUntil
New USD MPN4357 14370 2020-03-17

Frequently Asked Question

  • Q1. What are generic medicines?
    Generic medicines are the medicines that have the same active ingredients as that of the brand medicines but differ in inactive ingredients (ingredients that are used for coloring, preservation, etc.). Generics have the same side-effects, treatment, precautions, and dosage as that of the brand medicine. They are approved by WHO.
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    Generic medicines are cheap because they do not involve the cost of marketing, advertisement, promotion, attractive packaging, etc. All the brand medicines spend a lot of money on the aforementioned processes and the final cost is added to the product’s cost. Generic medicines are exclusive of this cost. These medicines are approved by WHO and completely safe to use.
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