Derise 100 Pre-filled Syringe

What is Derise 100

Derise 100 is a prescription injection used for treatment of anemia due to Chronic Kidney Disease (CKD) or Cancer. Its primary ingredient is Darbepoetin Alfa, an Erythropoiesis-stimulating Agent (ESA). Hetero Drugs Ltd manufactures Derise 100.

This medicine stimulates red blood cell production in the bone marrow by mimicking the Erythropoietin hormone. It helps increase hemoglobin levels and reduce the need for blood transfusions. The pre-filled syringe format ensures accurate dosing and convenient administration.

Common Derise injection side effects include headache, high blood pressure, nausea, fatigue, and injection site reactions. Severe side effects may include blood clots, stroke, or heart attack. Store the injection in the refrigerator between 2-8°C and protect from light. Do not shake the syringe before use.

Individuals with liver or kidney conditions should practice caution. Pregnant or breastfeeding women must ask a doctor before using Derise injection, as it may be harmful.

What are the benefits of Derise 100

Derise 100 works by binding to Erythropoietin receptors on red blood cell precursors in bone marrow. This stimulates the production of erythrocytes (red blood cells), increasing oxygen-carrying capacity throughout the body. The medication has a longer half-life than natural Erythropoietin, allowing less frequent dosing.

Key benefits include:

• Reduces symptoms of anemia, like fatigue and weakness.
• Decreases the need for blood transfusions.
• Improves the quality of life in Chronic Kidney Disease patients.
• Supports Cancer patients undergoing chemotherapy.

It is crucial to note that hemoglobin levels must be monitored regularly to avoid exceeding target ranges.

How to take Derise 100

Derise 100 is a prescription medication that should be administered as per your doctor's instructions. Here are the general guidelines:

• Administer Derise injection subcutaneously once weekly or once every two weeks as prescribed.
• Inject slowly under the skin in the thigh, abdomen, or upper arm. Rotate injection sites to prevent skin irritation.
• Do not exceed the prescribed Darbepoetin Alfa dosage or frequency.

Strengths and substitutes

The strengths and substitutes available at Cheap Medicine Shop are:

View all substitutes

What are the side effects of Derise 100

Derise is generally well-tolerated when used appropriately. However, it may cause side effects, including:

• Headache and dizziness
• High Blood Pressure (Hypertension)
• Nausea and vomiting
• Fatigue and weakness
• Injection site pain or swelling
• Muscle aches and joint pain
• Diarrhea

Most of these adverse effects typically do not require medical consultation and disappear as your body adjusts. Always seek medical guidance for severe effects.

Safety Advice

Liver disease

Patients with liver disease should use Derise with caution as hepatic impairment may affect drug metabolism. Regular monitoring of liver function tests is needed. Dose adjustments may be needed based on individual patient response and laboratory values.

Kidney impairment

Derise is primarily used in patients with CKD. However, those with severe kidney impairment require careful dose titration and frequent hemoglobin monitoring. Regular assessment of kidney function and electrolyte levels is essential during treatment.

Pregnant and breastfeeding women

Derise should be used during pregnancy only if the benefits justify the risks to the baby. It is unknown whether Darbepoetin Alfa passes into breast milk. Consult a healthcare professional before using the injection during pregnancy or breastfeeding.

Avoid

Avoid alcohol consumption, as it may worsen anemia symptoms. Do not take any iron supplements unless prescribed by your doctor. If experiencing dizziness, avoid activities requiring alertness. Do not use live vaccines without medical consultation.