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Glycomet GP (500+2) Mg, an oral antidiabetic medication, is used to manage Type 2 Diabetes Mellitus in adults. The tablet contains two FDA-approved active ingredients: Metformin (500 mg) and Glimepiride (2 mg). It belongs to the drug classes Biguanides (Metformin) and Sulfonylureas (Glimepiride) and is manufactured by USV Ltd, a reputable pharmaceutical company in India.
Metformin reduces glucose production in the liver, improving insulin sensitivity and decreasing glucose absorption from the intestine. Glimepiride stimulates the pancreas to release more insulin, lowering blood sugar levels. Together, these actions help maintain stable blood glucose, which also helps reduce the risk of developing Diabetes-related complications such as nerve damage, eye damage, and cardiovascular issues.
It should be taken orally with food, preferably at the same time daily per the doctor’s instructions. If a dose is missed, it should be taken as soon as possible, but skip it if it is almost time for the next dose. Overdose may cause severe Hypoglycemia, with symptoms like sweating, dizziness, or confusion. Seek immediate medical attention in such cases.
One common side effect of this medication is low blood sugar levels (Hypoglycemia). Carrying a quick glucose source, such as sugary food or fruit juice, is handy to manage these episodes. Other common side effects are nausea, diarrhea, headache, and stomachache.
The medication can interact with medicines like chloramphenicol, fenfluramine, pioglitazone, and medication for high blood pressure, raising the risk of Hypoglycemia (low blood sugar levels). It can also interact with contraceptives, acetazolamide, and phenytoin, increasing the risk of Hyperglycemia (high blood sugar levels). Alcohol causes low blood sugar levels and should be avoided.
Regular blood sugar monitoring and adherence to the doctor’s instructions are essential for safe and effective diabetes management with Glycomet GP (500+2) mg.
Glycomet 2 benefits patients with Type 2 Diabetes Mellitus in several ways:
Glycomet GP 2 is a prescription-based antidiabetic pill that should be taken under the doctor’s instructions. Here are the general guidelines for this medication:
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Glycomet 2 may cause some side effects, which are temporary and will subside in due time. However, if the symptoms continue or worsen, consult a doctor immediately.
Liver disease
Glycomet GP (500+2) Mg should be used cautiously in patients with liver disease, as impaired liver function can raise the risk of Lactic Acidosis from Metformin and Hypoglycemia from Glimepiride due to reduced drug clearance.
Kidney impairment
The medication should be used cautiously in kidney disease, as impaired function can cause Metformin buildup, risking Lactic Acidosis, and increase Glimepiride’s effects, raising the chance of Hypoglycemia and other side effects.
Pregnant and breastfeeding women
Although there are limited human studies on any defects regarding pregnancy, patients should take the medication with caution as directed by the doctor. The active salts can be excreted into milk, which is unsafe for infants and thus should be avoided.
Avoid
Due to low blood sugar levels (Hypoglycemia) as one of the side effects of this medication, alcohol consumption and driving should be avoided.
No, you should continue taking it as prescribed. Stopping suddenly can lead to uncontrolled blood sugar and complications. Always consult your doctor before making changes.
Yes, Glycomet-GP 2 Tablet PR can lead to Vitamin B12 deficiency, especially with long-term use. One of the active salts, Metformin, interferes with the absorption of vitamin B12 in the intestines, gradually lowering B12 levels in the body.
This medication is generally not recommended for children unless specifically prescribed by a pediatric endocrinologist.
You may notice some improvement in your blood sugar levels within a few days, but the full effect can take 1–2 weeks. Consistent use and regular monitoring are essential for better results.
You should tell your doctor if you have kidney or liver disease, metabolic acidosis, dehydration, severe infections, heart or lung failure, or if you are an alcoholic.
