Grafeel 300 Mcg Injection

Grafeel 300 Mcg Injection (Filgrastim)

What Is The Generic Name For Grafeel 300 Mcg Injection:

Filgrastim is the generic version for Grafeel 300 mcg Injection

Which USA Brand is Equivalent To Grafeel 300 Mcg Injection (Filgrastim):

• Grafeel

About Grafeel 300 Mcg Injection (Filgrastim)

Grafeel 300 mcg Injection contains an active ingredient, Filgrastim, which is used to prevent infections after chemotherapy. Filgrastim is an analog of human granulocyte colony-stimulating factor (G-CSF). It stimulates the growth of white blood cells & helps in decreasing the chances of infection in patients who are undergoing chemotherapy procedures for cancer. Patients with blood disorders are strictly advised not to use this medicine. This medicine is available at all the leading pharmacy, drugstores, & medical supply stores & must be taken strictly by doctor’s prescription only.

Manufacturer:

Dr Reddy's Laboratories Ltd. is one of the leading pharmaceutical companies which manufacture Grafeel 300 mcg Injection.  

Strength:

Grafeel 300 mcg Injection contains an active constituent, Filgrastim. It is obtainable in other substitutes also at all the leading online pharmacy, drugstores, and medical supply stores.

What Are The Uses Of The Grafeel 300 Mcg Injection (Filgrastim):

Grafeel 300 mcg Injection is used in the treatment in following conditions:

• Neutropenia caused by chemotherapy
• Bone Marrow Transplantation
• Peripheral Progenitor Cell Transplantation
• Chronic Neutropenia
• Neutropenia caused by radiation

How Grafeel 300 Mcg Injection (Filgrastim) Works:

Grafeel 300 mcg Injection has an active ingredient; Filgrastim is a growth factor which stimulates the bone marrow to produce white blood cells. These cells defend the body against infections. As a G-CSF analog, Filgrastim controls the proliferation of committed progenitor cells & influences their maturation into mature neutrophils. Filgrastim stimulates the release of neutrophils from bone marrow storage pools & decreases their time to maturation. Filgrastim works to increase the phagocytic activity of mature neutrophils, as a result allowing them to prevent infection. In patients getting cytotoxic chemotherapy, filgrastim can accelerate neutrophil recovery, which leads to a reduction in the duration of the neutropenic phase after chemotherapy.

Before You Use Grafeel 300 Mcg Injection (Filgrastim):

Make sure that:

• You are not allergic to Filgrastim
• You are not having any serious Disease
• Your doctor must be learned about your medicinal history like your pre- existing disease, surgeries & Medications, Supplements, Food Habits, lifestyle, etc.

What Should You Avoid While Taking Grafeel 300 Mcg Injection (Filgrastim):

• You should avoid taking alcohol  
• You should avoid driving
• You should avoid taking Medicines without prescriptions

When Not To Use Grafeel 300 Mcg Injection (Filgrastim):

You should not take Grafeel 300 mcg Injection if you:

• Have ever noticed any Allergy/Hypersensitivity
• Have liver problems
• Have kidney problems
• Are pregnant
• Have Splenic Rupture
• Have Acute Respiratory Distress Syndrome (ARDS)
• Have Sickle cell disease
• Have infections
• Are breastfeeding

Tell Your Doctor If You:  

• Have Allergy to the Injection
• Are taking Alcohol or Other Drugs
• Have Liver disease
• Have kidney disorder
• Have infections

Dosage:

Grafeel 300 mcg Injection contains an active ingredient, Filgrastim, which is used to prevent infections after chemotherapy. This medicine is available in different substitutes & strengths & has got to be purchased or given on doctor’s prescription only. You must consult your physician for adjustment of dosage & time of the medicine because age and severity of the disease differ from person to person and it can only be best judged by your doctor.

Adults are advised to take Grafeel 300 mcg Injection at a fixed time with or without food as instructed by your Doctor. You must take Grafeel 300 mcg Injection regularly on time for better results.

How Much Of The Grafeel 300 Mcg Injection (Filgrastim) to Be Used:

As Grafeel 300 mcg Injection is available in various strengths and substitutes, Patients are always advised to follow their doctor’s prescriptions and instructions to take Grafeel 300 mcg Injection. You must not take the Injection on your own & for longer period than recommended by doctor.

How To Take The Grafeel 300 Mcg Injection (Filgrastim):

Grafeel 300 mcg Injection should be taken at a fixed time as directed by your doctor. Your doctor or nurse will give you Grafeel 300 mcg Injection. Kindly do not self administer this medicine.

For How Long Should You Continue Using Grafeel 300 Mcg Injection (Filgrastim):

You are always advised to take Grafeel 300 mcg Injection as prescribed. Do not start/stop using this medicine yourself. You must strictly follow all the directions given by your doctor. You must not take the Injection in larger or smaller quantity or for longer period than suggested by your doctor.

Overdose:

You must seek out medical emergency treatment and/ or contact your surgeon without delay in case of any overdose symptoms. Since Grafeel 300 mcg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency measure will be initiated without delay by your physician if they observe overdose symptoms.

Missed Dose:

The missed dosage of the injection should be administered by the medical doctor as soon as possible. It is strictly recommended to skip the missed dosage if it is already time for your next planned dosage. You must not double the dosage of the treatment to make up for the missed dosage. Since Grafeel 300 mcg Injection is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dosage is very low.

What Are The Side Effects Of The Grafeel 300 Mcg Injection (Filgrastim):

• Stomach pain
• Hair loss
• Constipation
• Nausea or Vomiting
• Fever and chills
• Bone pain
• Loss of appetite
• Weight loss
• Swelling or inflammation of mouth
• Weakness
• Headache
• Rash
• Increased lactate dehydrogenase level in blood
• Increased uric acid level in blood
• Oropharyngeal pain
• Fatigue
• Diarrhea
• Cough
• Breathing difficulty

What Are The Common Drug Interactions:

Few medicines have been reported to interact with Grafeel 300 mcg Injection. These interactions may generate some needless or adverse effects and/or cause your drug not to work properly. You must always have a conversation with your doctor if you are taking other prescription/ Supplements so that well planned medication can be given. It interacts with the following medicines:

• Cisplatin
• Fluorouracil
• Doxorubicin

It can also interact with following disease condition:

• Infections
• Glomerulonephritis
• Myeloid Tumors
• Leukocytosis

Warning And Precaution:

Grafeel 300 mcg Injection can worsen the conditions like:

• Allergy
• Kidney/ Liver disease
• Grafeel 300 mcg Injection is not recommended for use in children under 18 years of age
• You must regularly get your blood tests done to monitor your blood cells, liver and kidney function, electrolyte levels and bone density during treatment with this medicine
• You must not take this medicine if you are pregnant, planning to conceive or breastfeeding
• You must not drive or operate heavy machinery at the same time as taking this medicine as it may cause dizziness
• Always consult with your medical doctor straight away to get best possible treatment if you are observing any of the above mentioned conditions.

Things To Remember:

• Keep the Grafeel 300 mcg Injection out of reach and sight of the children
• This medicine is strictly used with caution for treatment of children and elderly
• Grafeel 300 mcg Injection is not recommended for use in pregnant women due to the increased risk of harmful effects on the unborn baby
• You must always check up the information in particular written on the leaflet/ insert of the medicine
• Always consult with your medical doctor if you have any uncertainty in case of the dosage, time & strength of the medicine.

Indications:

Grafeel 300 mcg Injection should be taken for cancer treatment. Do not take this prescription for longer period than suggested by the medical doctor.

Storage:

Store the Grafeel 300 mcg Injection at room temperature in dark and dry place. Make sure the Injection is intact & not damaged while purchasing or storing.