Jardiance Met 5mg/500mg Tablet

What is Jardiance Met 5 mg 500 mg

Jardiance Met 5 mg 500 mg is a combination antidiabetic medication used to treat Type 2 Diabetes Mellitus in adults who are not adequately controlled on Metformin alone or those already treated with the combination of Empagliflozin and Metformin as separate tablets.

It contains two active ingredients: Empagliflozin (5mg), an SGLT2 inhibitor, and Metformin (500mg), a biguanide antihyperglycemic agent. Boehringer Ingelheim is the renowned marketer of Jardiance Met.

This dual-action medication improves glycemic control by enhancing Insulin sensitivity, reducing glucose production in the liver (Metformin), and increasing urinary glucose excretion (Empagliflozin). Common side effects include gastrointestinal disturbances, genital infections, and increased urination.

Store Jardiance Met in a cool, dry place below 25°C. Patients with severe kidney impairment, metabolic acidosis, or acute conditions that may affect kidney function should not take this medication. Always take with meals to minimize gastrointestinal side effects.

What are the benefits of Jardiance Met 5 mg 500 mg

Jardiance Met 5 mg 500 mg combines two complementary mechanisms of action to control blood glucose levels. Empagliflozin inhibits SGLT2 proteins in the kidneys, blocking glucose reabsorption and increasing urinary glucose excretion.

Simultaneously, Metformin reduces hepatic glucose production, improves peripheral glucose uptake, and delays intestinal glucose absorption.

The benefits of Jardiance Met include:

• More effective glycemic control than either component alone.
• Potential for weight reduction due to caloric loss from glucose excretion.
• Reduced risk of cardiovascular events and mortality.
• Lower systolic blood pressure
• Decreased risk of hospitalization for heart failure.

It is crucial to note that Jardiance Met should be used as an adjunct to diet and exercise for optimal Diabetes management.

How to take Jardiance Met 5 mg 500 mg

Jardiance Met 5 mg 500 mg is a prescription medication that should be taken as per your doctor's instructions. Here are the general guidelines:

• Take Jardiance Met twice daily with meals to reduce gastrointestinal side effects. Take at approximately the same times each day to maintain blood levels.
• Swallow tablets whole with a full glass of water.
• Take it with food.
• Do not exceed the prescribed maximum daily dose.

Strengths and substitutes

The strengths and substitutes of Jardiance Met 5/500 available at Cheap Medicine Shop are:

View all substitutes for Diabetes

What are the side effects of Jardiance Met 5 mg 500 mg

Jardiance Met 5 mg 500 mg generally has a manageable safety profile. However, it may cause side effects, including:

• Gastrointestinal issues (nausea, vomiting, diarrhea, abdominal pain)
• Genital yeast infections
• Urinary tract infections
• Increased urination

These adverse effects typically diminish over time as your body adjusts to the medication. However, contact your doctor immediately if you experience symptoms of lactic acidosis (severe fatigue, muscle pain, breathing difficulty), Diabetic Ketoacidosis, or severe allergic reactions.

Safety Advice

Liver disease

Jardiance Met should be used with caution in patients with liver disease. While no dose adjustment is required for mild liver impairment, the medication is not recommended for people with moderate to severe hepatic dysfunction due to the increased risk of lactic acidosis. Regular liver function tests are advised.

Kidney impairment

Kidney function should be assessed before starting and periodically during Jardiance Met therapy. This medication is contraindicated in individuals with moderate to severe kidney impairment. Elderly patients require closer monitoring of kidney function due to age-related decline in renal function.

Pregnant and breastfeeding women

Jardiance Met is not recommended during pregnancy as it may affect fetal development. Animal studies have shown potential risks. Women should use effective contraception during treatment. Breastfeeding is not advised while taking Jardiance Met as both active ingredients may pass into breast milk and potentially affect the nursing infant.

Avoid

Alcohol increases the risk of both lactic acidosis and Hypoglycemia, especially when combined with medications like Jardiance Met that contain Metformin. Iodinated contrast agents can cause kidney problems and should prompt temporary discontinuation of Jardiance Met before imaging procedures. NSAIDs, particularly in dehydration, may raise the risk of kidney injury. Excessive caffeine can worsen dehydration and may counteract some of the medication’s effects.