Lomustine 40 Mg

Lomustine 40 Mg (Lomustine)

What Is The Generic Name For Lomustine:

Lomustine is the generic version for Lomustine

Which US Brand is Equivalent To Lomustine 40 mg (Lomustine):

• CeeNU

About Lomustine 40 Mg (Lomustine):

Lomustine 40 mg contains an active ingredient, Lomustine, which is used in the treatment of blood cancer (Chronic myeloid leukemia), brain tumor, lung cancer, and gastrointestinal stromal tumor. This prescription-only drug is available at any of the leading pharmacy stores, drugstores, and medical supply stores.

Manufacturer:

GSK is one of the top leading pharmaceutical companies which manufacture Lomustine 40 mg.

Strength:

Lomustine 40 mg contains an active ingredient, Lomustine, 100 mg per capsule which is available in the various strengths and other substitutes at all the leading pharmacies, drugstores, and medical supply stores.

What Are The Uses Of The Lomustine 40 Mg (Lomustine):

Lomustine 40 mg is used in the treatment of:

• Blood Cancer (Chronic Myeloid Leukaemia)
• Gastrointestinal Stromal Tumor
• Bone marrow cancer
• Skin Cancer

How Lomustine 40 Mg (Lomustine) Works:

Lomustine partly acts as an alkylating agent (anti-cancer) and partly by inhibition of several steps in the synthesis of nucleic acid and inhibition of the repair of single-strand breaks in DNA chains.

Before You Use Lomustine 40 Mg (Lomustine):

Make sure that:

• You are not allergic to Lomustine
• You do not take alcohol
• Your doctor knows about your Pre-existing disease, Surgeries, Medications, Food Habits, Supplements, etc.

What Should You Avoid While Taking Lomustine 40 Mg (Lomustine):

• Avoid taking alcohol
• Avoid Smoking
• Avoid getting any cut or injury to the skin
• Avoid being in contact with people having any infection or inflammation
• Avoid taking Medicines without prescriptions

When Not To Use Lomustine 40 Mg (Lomustine):

You should not use Lomustine 40 mg if you:

• Have ever noticed any Allergy/Hypersensitivity to it
• Have Liver/Kidney Impairment
• Have recently received radiotherapy or any other cytotoxic agent
• Are Breastfeeding/Pregnant
• You must always consult your doctor for suitable and effective treatment

Tell Your Doctor If You:

• Have Allergy to it
• Have Blood Problems and Diabetes
• Have Liver/ Kidney Problems
• Had have any infection or received any vaccination
• Are suffering from breathing difficulty with fever or cough
• Have had a Surgery or have been operated recently
• Have recently received chemotherapy or radiotherapy
• Take Alcohol
• Are Pregnant/ Conceiving/ Breastfeeding
• Are having other Diseases, Drugs or Therapies

Dosage:

Lomustine 40 mg contains Lomustine, which is used in the treatment of Blood Cancer and Gastrointestinal Stomal Tumor. Lomustine 40 mg is a prescription-only drug and may be available in various strengths and other substitutes. Consult your doctor for the duration of dosage as age and severity of the disease differ from patient to patient.

It is not recommended for the Pediatric Population and children below18 yrs of age. It is strictly contraindicated for pregnant/Breastfeeding women and healthy people should not come in contact of this medicine as well as patient taking this medicine as it may be harmful. Man taking this medicine is not allowed to nurture his baby.

How Much Of The Lomustine 40 Mg (Lomustine) to Be Used:

Patients are always advised to follow their doctor’s prescriptions and instructions to take Lomustine 40 mg. Do not exceed the dose on your own as it may result in adverse effects. Also do not reduce the dose yourself as it will lead to non-satisfactory results.

How To Take The Lomustine 40 Mg (Lomustine):

Lomustine 40 mg dose should be taken at a fixed time and is to be taken with food and a glass full of water. Swallow the capsule as a whole with water without chewing or crushing it. It must be taken once after 6 weeks.

For How Long Should You Continue Using Lomustine 40 Mg (Lomustine)

You are always advised to take Lomustine 40 mg as prescribed by your doctor. You are not advised to take it for a shorter or longer time than recommended.

Overdose:

Contact your physician or reach a nearby medical facility immediately if you are suspecting the overdose symptoms like bone marrow and hematological toxicity, abdominal pain, diarrhea, anorexia, lethargy, dizziness, abnormal hepatic function, shortness of breath, etc. Overdose can be overcome by adopting the first measure of gastric lavage.

Missed Dose:

A missed dose of Lomustine 40 mg should be taken as soon as you remember. Skip the dose if it is the time for the next dose. Do not double the dose for next time if you missed once.

What Are The Side Effects Of The Lomustine 40 Mg (Lomustine)

• Diarrhea
• Nausea /Vomiting
• Loss of appetite
• Altered sense of taste
• Joint pain, stiffness, and swelling
• Difficulty in falling or staying asleep
• Skin rash, hives, or itching
• Hair loss or thinning of the hair
• Swelling of the hands, feet, ankle, around eyes, and lower legs
• Breathing Difficulty
• Bone marrow failure
• Thrombocytopenia, anemia, renal failure
• Anemia
• Azotaemia
• Renal atrophy/ injury
• Increased Transaminases
• Increased Blood Bilirubin (yellowing of the skin)
• Blood alkaline phosphatase increased
• Abnormal Coordination
• Disorientation
• Lethargy
• Pulmonary Fibrosis/ Lung Infiltration

What Are The Common Drug Interactions:

Lomustine 40 mg effects may interact with other medicines or other products you are using. It can produce some adverse effects or cause your drug not to work properly. Always discuss it with your doctor if you are on Vitamins, other Drugs or Herbal Supplements. Grapefruit juice is not recommended as it interacts with the drug. It interacts with the following medicines:

• Nitrosoureas
• Cimetidine
• Antiepileptic
• Phenobarbitone
• Nalidixic Acid
• Yellow Fever Vaccination
• Theophylline

It may interact with the few diseased conditions:

• Bone marrow Suppression
• Heart and blood vessels disorders
• Liver/ Kidney Disorders

Warning And Precaution:

Lomustine 40 mg should be used very cautiously or avoided in:

• Impaired Liver/Renal Function  
• Hypersensitivity/ Allergy
• Elderly usage
• Concomitant use of the live vaccine for yellow fever
• Growth Retardation
• Hypersensitivity to nitrosoureas
• Bone marrow depression
• Infections and inflammations
• Coeliac disease/wheat allergy
• Pregnant and breastfeeding women
• Consult your doctor to get the best possible treatment and dosage adjustment.

Things To Remember:

• Regular monitoring of blood cell count is needed while taking this medicine
• Keep out of sight as well as the reach of children
• Ask your doctor if you have any doubt related to the dosage, time, and the strength of the capsule

Indications:

• Do not stop taking/miss the dose of Lomustine 40 mg in between the course or do not increase or decrease the dose on your own. Strictly follow your doctor’s instructions.
• Use gloves while taking a dose. Do not use bare hands to take the medicine

Storage:

Store it at a cool temperature not more than 25 ̊C in a clean, dark and dry place. Make sure that the capsules should be intact and not damaged.