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Vagifem 25 Mcg

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Top priority medicine for the treatment of Hypoestrogenism and Primary ovarian failure. Shop Vagifem 25 Mcg this product from our online pharmacy
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USA Brand Name




Generic Name

 Estradiol Vaginal Tabs


 Novo Nordisk, Denmark


Vagifem 25 Mcg (Estradiol)

What Is The Generic Name For Vagifem:

Estradiol is the generic version for Vagifem

Which USA Brand is Equivalent To Vagifem 25 Mcg (Estradiol):

  • Estrace

About Vagifem 25 Mcg (Estradiol)

Vagifem 25 mcg contains an active ingredient, Estradiol, which is used in Hormonal Replacement therapy, Contraception, and Postmenopausal Osteoporosis. It must be used as prescribed by your doctor and also buy on prescription only from any of the leading pharmacy stores, drugstores, and medical supply stores.


German Remedies (India) is one of the top leading pharmaceutical companies which manufacture Vagifem 25 mcg. 


Vagifem 25 mcg contains Estradiol 25 mg per tablet that is available in the various strengths at all the leading pharmacy stores, drugstores, and medical supply stores. It is also available in different dosage forms and substitutes.

What Are The Uses Of The Vagifem 25 Mcg (Estradiol):

Vagifem 25 Mcg is used for:

  • Postmenopausal osteoporosis
  • Hypoestrogenism
  • Primary ovarian failure
  • End-stage breast cancer
  • Postmenopausal osteoporosis
  • Prostate Cancer
  • Oophorectomy

How Vagifem 25 Mcg (Estradiol) Works:

Vagifem 25 Mcg containing Estradiol is a female sex hormone produced by the ovaries in females. It acts by replacing the natural hormone in the body when the latter is deficient.

Before You Use Vagifem 25 Mcg (Estradiol):

Make sure that:

  • You are not allergic to it
  • You are not pregnant or breastfeeding
  • You are not taking alcohol
  • Your doctor knows about your medical histories like all your diseases, surgeries, medications you are taking, and all the supplements you are taking.    

What Should You Avoid While Taking Vagifem 25 Mcg (Estradiol):

  • Avoid taking alcohol
  • Avoid Grapefruit Juice
  • Avoid taking medicines without prescriptions

When Not To Use Vagifem 25 Mcg (Estradiol):

You should not take Vagifem 25 Mcg if you:

  • Have any allergy to Estradiol
  • Have Liver/Kidney/Heart Disease
  • Have Migraine
  • Develop yellowing of your skin or the whites of your eyes (jaundice) after using it
  • Have increased blood pressure
  • Have signs of a blood clot like painful swelling and redness of the legs, sudden chest pain, and difficulty in breathing.
  • Have Unexplained Vaginal Bleeding
  • Are Pregnant/Conceiving/Breastfeeding
  • Have Chest Pain, High Blood Pressure
  • Have Breast and Uterus Cancer or other Disorders

Tell Your Doctor If You:

  • Have any allergy to Estradiol
  • Have Liver/Kidney/Heart Disease
  • Have Blood Clotting Disorder
  • Have unexplained swelling and pain in your limbs, chest pain, shortness of breath, headache, high blood pressure, or changes in vision
  • Have Unexplained Vaginal Bleeding
  • Are Pregnant/Conceiving/Breastfeeding
  • Have Breast and Uterus Cancer or other Disorders


Vagifem 25 mcg contains, Estradiol, which is used for contraception and Osteoporosis. You may find in various strengths and substitutes and should be given on prescription only. You should consult your doctor for dosage, strength, duration and time.

Females are advised to take Vagifem 25 mcg at a fixed time as instructed by your Doctor. It must be taken with progesterone for contraception. You can start taking this between 21-28 days after your delivery and can start from the first day of your menstruation if you taking it the first time. If you got late to start this course then you have to choose an emergency contraception method for the first 7 days of the starting period and then can continue the same.

How Much Of The Vagifem 25 Mcg (Estradiol) to Be Used:

Patients are always advised to follow their doctor’s prescriptions and instructions to take Vagifem 25 mcg.

How To Take The Vagifem 25 Mcg (Estradiol):

Vagifem 25 mcg dose should be taken at a fixed time as directed by your doctor. Swallow the tablet as a whole with water without chewing or crushing the tablet. It is better to take it with or without food.

For How Long Should You Continue Using Vagifem 25 Mcg (Estradiol):

Patients are always advised to take Vagifem 25 mcg as prescribed by your doctor. Do not start/stop using this medicine yourself. Follow the instructions carefully given by the doctor. You are not advised to take it in a smaller or larger amount or for a longer time than recommended.


  • Contact your doctor immediately if you are suspecting the overdose symptoms like vomiting, Flu-like symptoms, Vaginal bleeding, etc.
  • Do not share your medicine with people around you

Missed Dose:

You should try to take every dose of Vagifem 25 mcg at a fixed time. But if you are less than 12 hrs late in taking your dose or if you vomit or have diarrhea, take the tablet as soon as possible but if you are more than 12 hrs late then you may seek emergency contraception. You just need to consult your doctor in that case.

What Are The Side Effects Of The Vagifem 25 Mcg (Estradiol):

  • Breast pain and tenderness
  • Vomiting
  • Weight gain
  • Dizziness
  • Depression
  • Back pain
  • Headache
  • Excessive Vaginal discharge
  • Flu-like symptoms
  • Excessive vaginal bleeding
  • Swelling of face, lips, eyelids, tongue, hands, and feet 
  • Troubled breathing and swallowing
  • Discharge from the nipple
  • Change in the texture of breast skin and nipples
  • Inverted nipples

What Are The Common Drug Interactions:

Few medicines have been reported to interact with Vagifem 25 mcg. It can produce some adverse effects or cause your drug not to work properly. Always discuss with your doctor if you are on other medication or supplements or you have pre-existing surgeries and diseases. Vagifem 25 mcg interacts with the following medicines:

  • Carbamazepine
  • Dexamethasone
  • Prednisolone
  • Warfarin
  • Thalidomide

This medicine also interacts with the following conditions and may cause life-threatening effects:

  • Heart and Blood Vessel Disorders
  • Estrogen-dependent Disorders
  • Breast and Uterus Cancer
  • Vaginal Bleeding
  • Pregnancy
  • It can also interfere with the lab tests:
  • Metyrapone test
  • Thyroid Function Test

Warning And Precaution:

Vagifem 25 Mcg is contraindicated in conditions like:

  • Hypersensitivity
  • Dementia
  • Jaundice-like Problems
  • Blood clotting problems and heart disease
  • Edema
  • Cardiovascular Disorders
  • Difference in Vision
  • Gall Bladder Disease and Diabetes
  • Pregnant and Breastfeeding women
  • Kidney and Liver Diseases
  • Always consult your doctor to get the best possible treatment

Things To Remember:

  • You should go for regular breast screening and cervical smear test while taking this contraceptive.
  • Keep out of reach and sight of the children
  • Read the information written on the leaflet of medicine carefully.
  • Always consult your doctor if you have any doubt related to the dose, time and strength of the Tablet.


It should be taken as prescribed by your doctor. Do not stop taking this tablet before completion of the course and also do not take it for a longer time than recommended.


Store the Vagifem 25 Mcg at room temperature in dark and dry place. Make sure that the tablets should be intact and tablets are not damaged.

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