Adriamycin 50 Mg Injection
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$218.50
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SKU
CMS2954
What is Adriamycin 50mg Injection
Adriamycin 50mg (Doxorubicin) is a powerful antineoplastic agent belonging to the anthracycline antibiotic class, used in chemotherapy to treat various types of cancer. Manufactured by Pfizer as a sterile red-colored solution for intravenous administration, this medication works by interfering with cancer cell DNA and preventing their multiplication.
It's commonly used in combination therapy protocols for treating breast cancer, lymphomas, leukemias, and other solid tumors. Side effects can be significant and include heart problems, bone marrow suppression, and nausea. Due to its potent nature, Adriamycin requires careful dosing based on body surface area and must be administered under close medical supervision in a healthcare setting.
What are the benefits of Adriamycin 50mg Injection
Adriamycin 50mg contains Doxorubicin, which functions through multiple mechanisms to combat cancer cells. It interacts with DNA, inhibiting both DNA and RNA synthesis, and interferes with topoisomerase II enzyme activity, leading to DNA damage and, ultimately, cancer cell death. The medication also creates free radicals that cause additional cellular damage, specifically to cancer cells.
Key benefits include:
- Effective against multiple types of cancer, including breast, lung, and bladder cancers.
- Demonstrates significant activity against lymphomas and leukemias.
- It can be used in combination with other chemotherapy drugs for enhanced effectiveness.
- Shows rapid activity against actively dividing cells.
It is crucial to note that treatment must be monitored due to the potential for serious side effects.
How to use Adriamycin 50mg Injection
Adriamycin 50mg is a prescription medication administered only by healthcare professionals in a controlled setting. Here are the general guidelines:
- Administered via slow intravenous injection.
- Dosing is calculated based on body surface area (BSA).
- Typically given in cycles with rest periods between treatments.
- Requires regular monitoring of heart, liver, and blood cell counts.
Strength and substitutes
Adriamycin has another strength that is available at Cheap Medicine Shop. The doctor will determine the accurate dosage depending on the condition and response. The strengths available for Adriamycin are:
| $49.50/ 1 Injection |
What are the side effects of Adriamycin 50mg Injection
Adriamycin 50 mg can cause side effects like:
- Nausea
- Vomiting
- Nail disorder
- Stomach pain
- Hair loss
These adverse effects may resolve quickly and do not require medical attention. However, if they worsen, see a doctor.
Safety Advice
Liver disease
People with liver impairment may require dose adjustments. Regular liver function monitoring is mandatory. Severe liver dysfunction may contraindicate use.
Kidney impairment
Careful monitoring is necessary, while no specific dose adjustments are required for kidney disease. Patients with severe kidney dysfunction may need modified dosing schedules.
Pregnant and breastfeeding women
Contraindicated during pregnancy due to high risk of fetal harm. Breastfeeding must be discontinued during treatment and for several weeks afterward.
Avoid
Avoid consumption of alcohol, grapefruit, and foods with turmeric during treatment.
FAQs
Is Doxorubicin a vesicant?
Yes, Adriamycin (Doxorubicin) is a potent vesicant that can cause severe tissue damage if extravasation (leakage of the medicine from the blood vessels) occurs. Administration requires strict and careful monitoring and immediate intervention if infiltration is suspected.
Can Adriamycin be mixed with other medications?
Adriamycin can be used in combination with a few other medicines. However, it should not be mixed with certain medicines like Heparin and Fluorouracil. It requires separate IV lines or thorough line flushing between different drug administrations. You should not mix two medications without consulting a doctor.
How does Adriamycin affect liver function?
Adriamycin is metabolized by the liver and can temporarily elevate liver enzymes. Regular monitoring of liver function is required, and dosing may need to be adjusted based on liver function tests.
What types of cancer is Adriamycin 50 Mg Injection typically used to treat?
Adriamycin is effective against multiple cancers, including breast cancer, lymphomas, leukemias, sarcomas, bladder cancer, and lung cancer. It's often used in combination therapy protocols.
What precautions should be taken during administration?
Careful IV site monitoring, the use of appropriate protective equipment for handlers, and regular cardiac monitoring are essential. An extravasation kit should be readily available during administration.