Moxclav 375 Tablet
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SKU
CMS7000
What is Moxclav 375
Moxclav 375 is an oral combination antibiotic used to treat several bacterial infections, including skin and soft tissue infections, Urinary Tract Infections (UTIs), respiratory tract infections such as Pneumonia, and dental infections. It is manufactured by Sun Pharmaceutical Industries in GMP-compliant facilities.
The tablet contains an FDA-approved combination of Amoxicillin (250 mg) and Clavulanic acid (125 mg) as its active ingredients. Amoxicillin is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis, leading to structural weakening of the bacterial cell wall and bacterial cell death.
Clavulanic acid is a beta-lactamase inhibitor that inactivates enzymes produced by certain bacteria that degrade Amoxicillin. This combination expands the antibacterial spectrum of the medicine. Moxclav 375 is taken orally as prescribed, usually 2-3 times daily with food. Taking it with meals helps reduce gastrointestinal discomfort and improves the absorption of clavulanic acid.
Common Moxclav side effects include nausea, diarrhea, and abdominal discomfort, which are generally mild and improve with continued use. Diarrhea occurs more frequently with this combination compared to amoxicillin alone due to the clavulanic acid component.
Before starting treatment, inform a doctor of any history of allergy to penicillin or cephalosporin antibiotics, as serious hypersensitivity reactions, including anaphylaxis, can occur. Also, inform a doctor of any liver or kidney disease. Store the tablets below 30°C in a dry, cool place, away from sunlight.
What are the benefits of taking Moxclav 375
Moxclav 375 tablet works by combining Amoxicillin's ability to destroy the bacterial cell wall with Clavulanic Acid's ability to block the enzyme that bacteria use to resist Amoxicillin, making it effective against a broader range of bacteria, including resistant ones. This combination makes it effective in treating:
- Community-acquired Pneumonia
- Sinusitis (Acute Bacterial Sinusitis)
- Otitis Media (middle ear infections)
- Skin and soft tissue infections
- Dental infections and dental abscesses
- Infected animal or human bites
How to take Moxclav 375
Moxclav 375 is a prescription medication that should be used as directed by a healthcare professional. Here are the general guidelines:
- Take as prescribed by a doctor. The dose and frequency depend on the type and severity of infection. It is typically administered 2-3 times daily.
- Swallow the tablet whole with a glass of water. Do not crush or chew.
- Take Moxclav 375 with food at the start of a meal to reduce stomach upset and improve the absorption of Clavulanic Acid.
- Do not exceed the prescribed dosage and complete the full antibiotic course even if symptoms improve before the course ends, to prevent recurrence and antibiotic resistance.
Strengths and Substitutes
Currently, Moxclav tablet is available in a single-strength option at Cheap Medicine Shop. However, you can consider the following effective alternatives:
| Augmentin 625 Duo Tablet | $11.10/10 tablets |
| Moxikind-CV 375 Tablet | $3.50/10 tablets |
What are the side effects of Moxclav 375
Moxclav can cause mild side effects that generally subside as the body adjusts to treatment. However, consult a healthcare professional if they persist or worsen:
- Nausea or vomiting
- Diarrhea or loose stools
- Stomach discomfort or bloating
- Skin rash or itching
- Headache
- Oral thrush with prolonged use
- Loss of appetite
Safety Advice
Liver Disease
Moxclav should be used with caution in patients with liver disease. This combination has been associated with a rare but recognized risk of cholestatic liver injury ( the flow of bile from the liver is reduced or blocked, leading to buildup of bile acids and liver inflammation), particularly in older patients or those receiving prolonged treatment. Inform a doctor of any liver conditions before starting this medication, as an alternative antibiotic may be more appropriate.
Kidney Impairment
Moxclav 375 should be used with caution in patients with kidney disease. Amoxicillin is primarily eliminated through the kidneys, while Clavulanic acid is partly cleared by the kidneys. Reduced kidney function can lead to the medicine accumulation, increasing the risk of side effects. A doctor may adjust the dose or extend the dosing interval based on kidney function. Always inform a doctor of any kidney conditions before starting treatment.
Pregnant and Breastfeeding women
Moxclav can be used during pregnancy when a doctor prescribes it. Both Amoxicillin and Clavulanic Acid pass into breast milk in small amounts. So, breastfeeding women should inform a doctor before use, as the infant may experience mild diarrhea or develop a skin rash.
Avoid
Do not use Moxclav in patients with a known allergy to penicillin antibiotics or cephalosporins. Do not use it for viral infections such as the common cold and flu, as antibiotics are ineffective against viruses and unnecessary use contributes to antibiotic resistance. Inform a doctor of all current medications before starting Moxclav 375, particularly anticoagulants such as Warfarin, as Amoxicillin can enhance their blood-thinning effects. Avoid alcohol during the course, as it can worsen stomach side effects.
FAQs
How long should the treatment be continued?
The duration of treatment with Moxclav 375 depends on the type of infection and its severity, typically ranging from 5 to 14 days. Mild infections may require 5-7 days, while more severe infections, such as Pneumonia, may need longer treatment. Always complete the full prescribed course.
Can Moxclav 375 cause diarrhea or stomach upset?
Yes, diarrhea and stomach upset are common with Moxclav 375, mainly due to Clavulanic acid. Taking it with food reduces these effects. Seek medical advice if diarrhea is severe, persistent, or contains blood, as this may indicate a serious intestinal condition.
Is Moxclav 375 safe for children?
Moxclav 375 tablets are generally prescribed for adults. In children, this Amoxicillin and Clavulanic Acid is available as syrups or dispersible tablets with weight-based dosing. A doctor should determine the appropriate formulation and dose before use in pediatric patients.
Can Moxclav 375 be used for viral infections?
No. Moxclav is effective only against bacterial infections. It does not work for viral illnesses such as the common cold or influenza. Unnecessary use can cause side effects and contribute to antibiotic resistance. Always confirm the need for antibiotics with a doctor.
Can Moxclav 375 be taken on an empty stomach?
No, Moxclav should be taken at the start of a meal or after a meal. Taking it with food improves absorption of Clavulanic acid and reduces the risk of nausea, stomach discomfort, and diarrhea, improving overall tolerability.
What should be done if a dose of Moxclav 375 is missed?
If a dose of Moxclav is missed, take it as soon as remembered. If it is close to the next dose, leave the missed one and continue the regular schedule. Do not take two doses together, as this increases the risk of side effects.
Is Moxclav 375 safe for patients with penicillin allergy?
No. Moxclav 375 contains Amoxicillin, a penicillin antibiotic. It should not be used in patients with penicillin allergy due to the risk of severe reactions, including anaphylaxis. Always inform a doctor about any antibiotic allergies before starting treatment.
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