Enjoy Free Shipping on Orders above $220
10% off on orders over $120 up to $20 Use Code: MYVAL10
Sepnil 400 mg/80 mg tablet is an antibiotic combination designed to treat various bacterial infections affecting the urinary tract, respiratory system, gastrointestinal tract, and other body parts. The medicine contains a combination of FDA-approved ingredients: Sulfamethoxazole (400 mg) and Trimethoprim (80 mg), which belong to the sulfonamide class of antibiotics. Tosc International, India, manufactures these tablets in GMP-compliant facilities.
This antibiotic combination works synergistically by blocking two consecutive steps in the bacterial synthesis of folic acid, which is important for bacterial growth and reproduction. Sulfamethoxazole inhibits the incorporation of para-aminobenzoic acid into folic acid, while Trimethoprim blocks the reduction of dihydrofolic acid to tetrahydrofolic acid. This dual mechanism makes the combination highly effective against a wide range of bacteria.
The recommended dosage is typically one to two tablets taken twice daily, with doses spaced 12 hours apart. The tablets should be taken with a full glass of water, and it is important to maintain adequate fluid intake during treatment. The complete course should be finished even if symptoms improve to prevent antibiotic resistance.
Common Sepnil side effects may include nausea, vomiting, loss of appetite, diarrhea, headache, and skin rash. These are generally mild and temporary, resolving as your body adjusts to the antibiotic. Contact your doctor if any of these side effects become severe or worsen.
Before taking Sepnil 400 mg/80 mg, inform your doctor about your complete medical history, especially if you have kidney disease, liver disease, blood disorders, Asthma, severe allergies, or Glucose-6-phosphate dehydrogenase (G6PD) deficiency. Pregnant and breastfeeding women should use this medicine only under strict medical supervision.
Store Sepnil 400 mg/80 mg tablet in a cool, dry place away from sunlight and moisture, and keep it out of reach of children.
Sepnil 400 mg/80 mg tablet offers multiple benefits for individuals dealing with bacterial infections:
Sepnil is a prescription-based antibiotic that should be taken as per a healthcare professional's instructions. Here are the general guidelines for taking this medicine:
Sepnil is available in only a single-strength option. However, you can consider these effective alternatives:
| Bactrim DS Tablet | $0.50/10 tablets |
| Antrima DS 800 mg/160 mg Tablet | $0.50/10 tablets |
Like any medicine, Sepnil 400 mg/80 mg tablet may cause some side effects. Most of them are temporary and will subside as the body adjusts. However, consult a healthcare professional if they persist or worsen:
Liver Disease
Patients with liver disease should use Sepnil with caution. The medicine is metabolized by the liver, and impaired liver function might increase the risk of side effects. The doctor may need to adjust the dosage or monitor liver function regularly during treatment.
Kidney Impairment
Individuals with kidney disease should use Sepnil with extreme caution. The medicine is eliminated through the kidneys, and impaired kidney function can cause accumulation and increased toxicity. Dose adjustments are needed for patients with moderate to severe kidney impairment, and adequate hydration is essential.
Pregnant and Breastfeeding women
Pregnant and breastfeeding women should use Sepnil only under strict medical supervision. The medicine can cross the placenta and pass into breast milk. It should be avoided during the third trimester of pregnancy due to the risk of jaundice in newborns, and it is generally not recommended during breastfeeding.
Avoid
Do not take Sepnil if you are allergic to Sulfamethoxazole, Trimethoprim, sulfonamides, or any other ingredients in the tablet. Avoid this medicine in cases of blood disorders such as Anemia or low platelet count. Do not use it in infants younger than 2 months old. Avoid excessive sun exposure as this medicine can cause photosensitivity. Limit alcohol consumption during treatment. Do not take it with certain medicines, such as Methotrexate or blood thinners, without consulting your doctor.
Sepnil tablet mg typically begins working within 1-2 days of starting treatment. Most people notice improvement in symptoms within 2-3 days. However, you must complete the full prescribed course, usually 5-14 days depending on the infection, to ensure complete bacterial elimination and prevent resistance.
No, Sepnil 400 mg/80 mg is an antibiotic that only treats bacterial infections. It is completely ineffective against viral infections like the common cold, flu, or most sore throats. Taking antibiotics for viral infections contributes to antibiotic resistance and exposes you to side effects.
No, Sepnil 400 mg/80 mg does not reduce the effectiveness of birth control pills. However, if you experience vomiting or diarrhea while taking this antibiotic, it may affect the absorption of your birth control. Use additional contraceptive methods if you experience gastrointestinal side effects.
No, alcohol consumption should be limited or avoided while taking Sepnil 400 mg/80 mg. Alcohol may increase the risk of side effects like nausea, vomiting, and headache, and may also reduce the effectiveness of the antibiotic. It can also increase the risk of liver toxicity.
If you develop a skin rash while taking Sepnil 400 mg/80 mg, stop taking the medicine immediately and contact your doctor. Rashes can indicate an allergic reaction, which can be mild to severe, including Stevens-Johnson syndrome, a serious condition requiring immediate medical attention.
Yes, Sepnil 400 mg/80 mg can cause photosensitivity, making your skin sensitive to sunlight. You may sunburn more easily while taking this medicine. Use sunscreen, wear protective clothing, and avoid sun exposure during treatment to prevent severe sunburn and skin damage.
No, you should not stop taking Sepnil 400 mg/80 mg even if you feel better. Stopping antibiotics early allows bacteria to survive and develop resistance, which can lead to recurrent or more severe infections. Always complete the full prescribed course as directed by your doctor.
