Apoxet 60 mg
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What is Apoxet 60
Apoxet 60 mg is a medication for Premature Ejaculation (PE). It contains an FDA-approved active ingredient called Dapoxetine, which belongs to the medication class Selective Serotonin Reuptake Inhibitor (SSRI). Alpha Pharmaceuticals manufactures Apoxet.
Dapoxetine basically functions by increasing Serotonin levels in the nervous system. Increased levels allow for Delayed Ejaculation and improve control. Consult a doctor for a suitable dosage. General dosage guidelines state taking 1 tablet of 60 mg 60-180 minutes before indulging in sexual activity. Do not chew or crush the tablet. Note that the medication can have some temporary and mild side effects, including dizziness or blurred vision. Consult a doctor if these persist for a long time.
For safe use, keep the tablets below 30°C. Protect them from sunlight and moisture. Keep them out of the reach of pets and children. Avoid using them once the medicine expires, and dispose of them properly. Be cautious as medications like Antibiotics, such as Linezolid, and Antifungals, such as Fluconazole or Itraconazole, can interact with Dapoxetine. They increase the side effects of PE control medicine by impacting its breakdown in the body. Monoamine Oxidase Inhibitors (MAOIs) can also show interaction and result in Serotonin Syndrome (severe increase in Serotonin levels). Interaction with Tricyclic Antidepressants also elevates the risk of Serotonin Syndrome.
What are the benefits of taking Apoxet 60
Apoxet 60 (Dapoxetine) is a short-acting SSRI for Premature Ejaculation. Serotonin's function is linked with brain regions involved in ejaculatory control. So, Dapoxetine's prime function is to increase the concentration of Serotonin. Increased Serotonin activity delays ejaculation.
Dapoxetine 60mg is quickly absorbed and eliminated. This makes it suitable for on-demand use shortly before a planned sexual activity. Some other benefits are:
- It improves a man's control over ejaculation, increasing overall sexual satisfaction.
- It lowers personal frustration related to PE, enhancing psychological well-being.
- It has a better safety profile than traditional SSRIs used off-label for PE.
How to take Apoxet 60
Apoxet is a prescription PE tablet. Therefore, you will need a doctor’s guidance to administer an accurate dose. The general dosage guidelines are as follows:
- Take 1 tablet and swallow as a whole.
- Take it at least 1-3 hours before planned sexual activity.
- Avoid taking more than 1 dose in a 24-hour period.
- Medication can be taken with or without food.
A high-fat meal can slightly lower the plasma concentration and rate of absorption of Dapoxetine.
Strengths and Substitutes
Currently, only substitutes are available at Cheap Medicine Shop, including:
| Dapotime 60 mg | $7.00 / 10 tablets |
| Duratia 90 mg | $10.20 / 10 tablets |
| Poxet 30 mg | $42.50 / 10 tablets |
What are the side effects of Apoxet 60
Apoxet 60 mg has some common side effects like any other medicine. These effects are generally mild and of a short duration. Effects are:
- Dry mouth
- Fatigue
- Headache
- Nausea
- Dizziness
- Digestive issues
Contact a doctor in case of severe side effects, such as vision changes or mood swings.
Safety Advice
Liver Disease
Individuals with liver impairment should use it with caution. In case of severe disease, Dapoxetine breakdown can be affected, elevating the risk of side effects.
Kidney Impairment
Dapoxetine is not recommended for end-stage kidney disease or severe renal impairment. These conditions can impact the body’s elimination of Dapoxetine. In mild to moderate kidney conditions, consult a doctor and use with caution.
Pregnant and breastfeeding women
Safety data for pregnant and breastfeeding women is limited. Apoxet 60 mg tablets are directed for men dealing with PE.
Avoid
Avoid grapefruit juice as it can boost Dapoxetine levels in the blood, increasing the risk of side effects. Also, avoid alcohol as it can increase the risk of fainting or dizziness.
FAQs
Is Dapoxetine safe for the heart?
Yes, Dapoxetine is usually considered safe for the heart. However, it is important to stick to the doctor's recommended dosage. Medical studies have shown that Dapoxetine does not trigger any adverse effects on heart rhythm. Also, informing the doctor of any heart condition before starting PE treatment is essential.
What happens if you take too much Dapoxetine?
If you take too much Dapoxetine, it can cause an overdose. Symptoms will include tremors, rapid heartbeat, sudden drop in blood pressure (Orthostatic Hypotension), fainting, and vomiting. It can also lead to Serotonin Syndrome, characterized by muscle rigidity, high fever, and irregular heartbeat.
How long does Dapoxetine stay in your body?
Dapoxetine 60 mg will stay in your body for 4-5 days, considering its half-life is 21.9 hours. Half-life is the time it takes a medicine to reduce its concentration by half (50%) in the body. However, its effect only lasts 8-12 hours.
What should I tell my doctor before taking Dapoxetine?
Before taking Dapoxetine, tell your doctor about your complete medical history. You should particularly inform about sexual health conditions, including Erectile Dysfunction, history of Epilepsy, heart conditions, and low blood pressure. Your doctor should also know about any bleeding disorder you have.
Can I use Tadalafil with Dapoxetine?
Yes, you can use Tadalafil with Dapoxetine. This combination is often used to treat PE and Erectile Dysfunction together. While Dapoxetine is an SSRI, Tadalafil is a Phosphodiesterase Type-5 (PDE-5) inhibitor. Using them in combination can enhance sexual performance by addressing two sexual conditions.
Can a normal person take Dapoxetine?
No, a normal person without a PE diagnosis is usually recommended against using Dapoxetine. It is particularly developed and FDA-approved for men with PE. Taking Dapoxetine tablets without a medical indication can expose them to the risk of side effects.
Why is Dapoxetine not working?
Dapoxetine may not be working for you for several reasons. Insufficient dosage or incorrect timing of medication use can also impact its effectiveness. If Dapoxetine is not working for you, it is better to consult a healthcare professional.
Citation: PubMed Central